口腔医学研究

口腔医学研究 ›› 2017, Vol. 33 ›› Issue (9): 974-977.DOI: 10.13701/j.cnki.kqyxyj.2017.09.016

• 临床研究论著 • 上一篇    下一篇

心内科住院患者冠心病发病风险与缺牙数目相关性的临床研究

周团团1，王冲1，张丽贞2，王丙娜1，刘欣1，续彩霞1，任秀云1*   

  1. 1. 山西医科大学口腔医学系 山西 太原 030001；
    2. 山西省心血管病医院心内科 山西 太原 030024
  • 收稿日期:2017-02-10 出版日期:2017-09-20 发布日期:2017-09-27
  • 通讯作者: 任秀云,电话:0351-4690838
  • 作者简介:周团团(1990~ ),男,山西晋城人,硕士在读,主要从事牙周与心血管病的研究。
  • 基金资助:
    国家自然科学基金项目(编号:81271144、31050002)

Clinical Study on Relationship between Risk of Coronary Heart Disease and Number of Tooth Loss in In-patients of Department of Cardiology

ZHOU Tuan-tuan1, WANG Chong1, ZHANG Li-zhen2, WANG Bing-na1, LIU xin1, XU Cai-xia1, REN Xiu-yun1*   

  1. 1. Department of Stomatology, Shanxi Medical University, Taiyuan 030001, China;
    2. Department of Cardiology, Cardiovascular Disease Hospital of Shanxi Province, Taiyuan 030024, China.
  • Received:2017-02-10 Online:2017-09-20 Published:2017-09-27

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摘要： 目的:探讨冠心病发病风险与牙齿缺失数目之间的相关关系。方法:选取2016年5~11月因胸痛于山西省心血管病医院心内科住院的506名患者为研究对象,对其进行统一问卷调查及口腔临床检查,记录基本信息、全身情况、口腔状况。依据纳入标准,最终纳入328例研究对象,根据冠脉造影结果,将其分为非冠心病组(主要血管管腔直径狭窄程度<50%)、单支病变组、双支及以上病变组进行相关性分析。结果:单因素分析结果显示,年龄,性别,吸烟史,牙龈指数,缺牙数目差异均有统计学意义(P<0.05)。ordinal logistic回归分析显示,缺牙数目为冠心病发病的主要危险因素,与无缺牙相比,缺牙数目为1~5颗时,冠心病发病风险增加83%(OR=1.825,95%CI=1.074-3.1),当缺牙数目超过5颗以上时,冠心病发病风险增加1.65倍(OR=2.65,95%CI=1.471-4.956)。结论:对于本研究的心内科住院人群,缺牙数目可能是冠心病发病风险增加的独立危险指标,并且随着牙齿缺失数目的增多,风险随之升高;随着年龄增加,风险增加;男性的风险较女性高。

关键词: 冠心病, 冠状动脉造影术, 缺牙数目

Abstract: Objective: To explore the correlation between the risk of coronary heart disease (CHD) and the number of tooth loss. Methods: Totally 506 in-patients result from chest pain were involved in Department of Cardiology of Cardiovascular Disease Hospital of Shanxi Province from May 2016 to November 2016. Basic information, oral health status, and general condition were collected using a standardized questionnaire. Based on the inclusion criteria, finally 328 cases were included in the research. According to the results of coronary angiography, three groups were divided:the non CHD group (degree of major vascular lumen diameter stenosis<50%), the single lesion group, and double or more lesions group. Results: The single factor analysis showed that age, gender, smoking, gingival index, and the number of tooth loss, were statistically significant (P<0.05). The ordinal logistic regression analysis showed that the number of tooth loss was a major risk factor for CHD incidence. Compared with no tooth loss, when the number of tooth loss was between 1-5, the risk of CHD increased by 83% (OR=1.825, 95% CI=1.074-3.1). When the number of tooth loss exceeded 5, the risk of CHD increased 1.65-fold (OR=2.65, 95% CI=1.471-4.956). Conclusion: In this in-patient, the number of tooth loss may be an independent risk indicator of increasing the incidence of CHD, and with the increasing of the number of tooth loss, the risk increasing; The risk inreased with age; And the risk of men was gredter than women.

Key words: Coronary heart disease , Coronary angiography , Tooth loss

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