口腔医学研究

口腔医学研究 ›› 2019, Vol. 35 ›› Issue (9): 889-893.DOI: 10.13701/j.cnki.kqyxyj.2019.09.017

• 口腔肿瘤学研究 • 上一篇    下一篇

颌骨牙源性硬化性癌的影像学特征分析及文献复习

帕克扎提·色依提1, 张磊2, 王铁梅1*, 黄晓峰2, 林梓桐1, 孙国文3   

  1. 1. 南京大学医学院附属口腔医院,南京市口腔医院口腔颌面医学影像科 江苏 南京 210008;
    2. 南京大学医学院附属口腔医院,南京市口腔医院口腔病理科 江苏 南京 210008;
    3. 南京大学医学院附属口腔医院,南京市口腔医院口腔颌面外科 江苏 南京 210008
  • 收稿日期:2019-01-06 出版日期:2019-09-28 发布日期:2019-09-25
  • 通讯作者: 王铁梅,E-mail:tiemei106@263.net
  • 作者简介:帕克扎提·色依提(1992~ ),女,新疆乌鲁木齐人,硕士在读,主要从事口腔颌面医学影像学研究工作。
  • 基金资助:
    江苏省自然科学基金面上项目(编号:BK20150089);南京市医学科技发展资金(编号:QRX17079)

Imaging Features Analysis of Odontogenic Sclerosing Carcinoma and Literature Review

Pakezhati Seyiti1, ZHANG Lei2, WANG Tiemei1*, HUANG Xiaofeng2, LIN Zitong1, SUN Guowen3   

  1. 1. Department of Radiology, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing 210008, China;
    2. Department of Oral Pathology, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing 210008, China;
    3. Department of Oral and Maxillofacial Surgery, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing 210008, China.
  • Received:2019-01-06 Online:2019-09-28 Published:2019-09-25

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摘要： 目的:探讨颌骨牙源性硬化性癌的临床及影像学特征,结合文献提出影像学分型,以期提高对颌骨这一罕见疾病影像鉴别诊断和认识。方法:经我院收治且病理证实的颌骨罕见的牙源性硬化性癌1例,回顾性分析影像学表现、组织病理学检查、免疫组化及分子检测结果等,结合文献复习对该病影像学诊断及鉴别诊断进行探讨。结果:本例影像学表现主要为下颌骨弥漫性不规则腔状低密度骨质吸收影,混杂斑片样高密度成骨征象,边界欠清,周缘骨质增生硬化,下颌骨体部膨隆明显,颊舌侧骨皮质吸收并见层状骨膜成骨。结合文献复习提出影像学分型:局限型、弥漫型、软组织肿物型。结论:颌骨牙源性硬化性癌是一种非常罕见的疾病,缺少特征性影像学表现,更多病例报道对于帮助准确诊断这一罕见疾病至关重要。

关键词: 牙源性硬化性癌, 骨质吸收, 影像学分型

Abstract: Objective: To investigate the clinical and imaging features of sclerosing odontogenic carcinoma (SOC) and discuss its differential diagnosis after reviewing the literatures. Methods: The radiological and pathological appearances of a case diagnosed pathologically as SOC in our hospital were retrospected and summarized. After reviewing the literatures, its imaging diagnosis and differential diagnosis were discussed. Results: In our case, the lesion occupied the right mandible body to the left mandible ascending branch area, and showed irregular cavity-shaped radiolucency with an unclear border mixed with a patchy high density of ossifies. Obvious thickening was present on mandible body, the buccal and lingual cortex were absorbed, and osteogenesis of periosteum was also exists. According to literature review, the imaging classifications were proposed as localized type, diffuse type, and soft tissue mass type. Conclusion: As an extremely rare disease, the imaging manifestations of odontogenic sclerosing carcinoma are complex and diverse, but lack of characteristics. More case reports are quite essential to precisely diagnose this disease.

Key words: sclerosing odontogenic carcinoma, bone resorption, imaging classification