口腔医学研究 ›› 2016, Vol. 32 ›› Issue (2): 189-190.DOI: 10.13701/j.cnki.kqyxyj.2016.02.021

• ·临床研究论著· • 上一篇    下一篇

蛇毒血凝酶减少拔牙术后出血的临床研究

李明恒 于鑫* 邵本春 贺平 马卫东   

  1. 大连市口腔医院口腔外科 辽宁 大连 116021
  • 收稿日期:2015-07-21 出版日期:2016-02-28 发布日期:2016-03-10
  • 通讯作者: 于鑫,E-mail:yuxin_dentist@qq.com
  • 作者简介:李明恒(1984~),男,重庆人,主治医师,硕士,主要从事口腔外科方面研究。

Effect of Hemocoagulase Injection on Reducing Bleeding after Tooth Extraction.

LI Ming-heng, YU Xin, SHAO Ben-chun, HE Ping, MA Wei-dong.   

  1. Dalian Stomatological Hospital, Dalian 116021, China
  • Received:2015-07-21 Online:2016-02-28 Published:2016-03-10

摘要: 目的:通过观察蛇毒凝血酶在下颌低位埋伏阻生智齿拔除术中应用与否的术后出血情况,评价蛇毒凝血酶在减少拔牙术后出血方面的临床疗效。方法:将需拔除下颌低位埋伏阻生智齿的267例患者随机分为试验组与对照组,试验组术前0.5 h局部注射蛇毒凝血酶1单位,其它操作相同。结果:试验组135例中,术后40 min出血0例,24 h后出血1例;对照组132例中,术后40 min出血5例,24 h后出血7例。两组数据比较均有统计学意义(P<0.05)。结论:蛇毒血凝酶在拔牙术中应用可有效减少术后出血。

关键词: 蛇毒血凝酶注射液, 低位下颌阻生智齿, 牙拔除术

Abstract: Objective: To evaluate the haemostatic effect of hemocoagulase injection on the extraction of mandibular impacted wisdom teeth. Methods: Two hundred and sixty-seven cases were randomly divided into the experimental group (135 cases) and the control group (132 cases). The experimental group received the same extraction procedure as the control group, except a local injection of 1U hemocoagulase half an hour before the operation. Results: There was no bleeding case in the experimental group 40 minutes after the extraction, and 1 bleeding case after 24 hours. However, there was 5 bleeding cases 40 minutes after the extraction and 7 bleeding cases after 24 hours in the control group. Statistical analysis showed significant difference between two groups (P<0.05). Conclusion: Hemocoagulase injection before tooth extraction was effective on theh reducing of postoperative bleeding.

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