口腔医学研究

口腔医学研究 ›› 2018, Vol. 34 ›› Issue (12): 1368-1372.DOI: 10.13701/j.cnki.kqyxyj.2018.12.025

• 其他研究 • 上一篇    

3例颌骨角化型成釉细胞瘤:病例报道及影像学特征分析

冯英连1,张磊2,王铁梅1*,林梓桐1,刘澍1,黄晓峰2   

  1. 1. 南京大学医学院附属口腔医院,南京市口腔医院口腔颌面医学影像科 江苏 南京 210008;
    2. 南京大学医学院附属口腔医院,南京市口腔医院口腔病理科 江苏 南京 210008
  • 收稿日期:2018-03-15 出版日期:2018-12-28 发布日期:2018-12-27
  • 通讯作者: 王铁梅,E-mail:tiemei106@263.net
  • 作者简介:冯英连(1989~ ),女,江苏徐州人,医师,主要从事口腔颌面影像的研究工作。
  • 基金资助:
    江苏省自然科学基金面上项目(编号:BK20150089)江苏省南京市医学科技发展项目(编号:YKK15116)南京市医学科技发展资金资助(编号:QRX17079)

Keratoameloblastoma: 3 Cases Report and Imaging Features Analysis.

FENG Ying-lian1, ZHANG Lei2, WANG Tie-mei1*, LIN Zi-tong1, LIU Shu1, HUANG Xiao-feng2   

  1. 1. Department of Oral and Dentomaxillofacial Radiology, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing 210008, China;
    2. Department of Oral Pathology, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing 210008, China.
  • Received:2018-03-15 Online:2018-12-28 Published:2018-12-27

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摘要： 目的: 探讨角化型成釉细胞瘤的影像学特征,并结合文献资料讨论其影像学鉴别诊断。方法: 搜集2011~2017年我院经病理证实罕见的角化型成釉细胞瘤3例,回顾性分析并总结3例角化型成釉细胞瘤的影像学特征,并结合现有文献对于其鉴别诊断进行探讨。结果: 3例角化型成釉细胞瘤中,发病部位均位于左下颌骨体和升支部,共同的影像学特征为膨胀性不均匀密度影,边界呈扇贝样及虫蚀状,其内见不均匀性稍高密度影,部分伴有钙化致密影。结合文献,其主要与原发性骨内鳞状细胞癌、恶性成釉细胞瘤及颌骨中央性巨细胞病变进行鉴别。结论: 角化型成釉细胞瘤影像学上同时兼具良性及恶性特征表现。识别典型角化型成釉细胞瘤的影像学特征有助于本病的诊断及手术方案制定,此外更多的病例报道对于可以准确诊断这一罕见的角化型成釉细胞瘤至关重要。

关键词: 化型成釉细胞瘤, 影像特征, 鉴别诊断

Abstract: Objective: To investigate the imaging features of keratoameloblastoma (KA) and discuss its differential diagnosis after reviewing the literatures.Methods: Three patients who were diagnosed pathologically as KA were involved in this study from 2011 to 2017 in the Department of Oral and Maxillofacial Radiology.The radiological appearances were retrospected and summarized.After reviewing the literatures, its differential diagnosis was discussed.Results: Among 3 cases, the lesions were all located in the left side of mandibular body and ascending branch.The common radiological findings were expansible inhomogeneous lesions with septa, as well as scalloping and worm-eat borders.Heterogeneous high attenuation foci intermixed with areas were found, part of which had scarred calcification.The differential diagnosis included primary intraosseous carcinomas, malignant ameloblastoma, and central giant cell lesion.Conclusion: Both benign and malignant radiological characteristics can be seen on the imaging of KA.The identification of typical radiographic features is helpful to diagnose the KA and make surgical decision.More case reports are important to precisely diagnose this extremely rare histological ameloblastoma.

Key words: Keratoameloblastoma, Radiographic features, Differential diagnosis