2025全球念珠菌病诊断与管理指南:口腔临床实践核心要点解读

doi:10.13701/j.cnki.kqyxyj.2026.03.001

口腔医学研究 ›› 2026, Vol. 42 ›› Issue (3): 179-185.DOI: 10.13701/j.cnki.kqyxyj.2026.03.001

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2025全球念珠菌病诊断与管理指南:口腔临床实践核心要点解读

刘志盈, 杨津^*, 周红梅^*

口腔疾病防治全国重点实验室国家口腔医学中心口腔疾病国家临床医学研究中心口腔医学⁺前沿医学创新中心四川大学华西口腔医院口腔黏膜病科四川成都 610041

收稿日期:2025-08-15 发布日期:2026-03-26
通讯作者: * 杨津,E-mail:yangjin@scu.edu.cn
周红梅,E-mail:zhouhm@scu.edu.cn
作者简介:刘志盈(2002~ ),女,重庆人,硕士在读,研究方向:口腔黏膜病学。
基金资助:
国家自然科学基金(编号:82573832);四川省科技计划(编号:2024YFHZ0323)

2025 Global Guideline for the Diagnosis and Management of Candidiasis: Interpretation of Core Points for Oral Clinical Practice

LIU Zhiying, YANG Jin^*, ZHOU Hongmei^*

State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Frontier Innovation Center for Dental Medicine Plus & Department of Oral Medicine, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China

Received:2025-08-15 Published:2026-03-26

摘要/Abstract

摘要： 欧洲医学真菌学联盟、国际人类和动物真菌学学会及美国微生物学会于2025年2月联合颁布了《全球念珠菌病诊断与管理指南》。该指南基于高质量循证医学证据与专家共识,系统地阐述了念珠菌病的最佳诊断与管理策略,核心内容包括:危险因素分层与性别差异、病原学更新及菌种变迁、临床表现多维解析、诊断技术分层推荐、疾病管理阶梯路径及分级防控临床策略。本文聚焦该指南中口腔念珠菌病的核心要点进行解读,结合最新研究进展进行分析与讨论,旨在为口腔临床医师提供规范化诊疗参考,促进我国口腔念珠菌病诊疗水平的提升。

关键词: 念珠菌病,口腔, 指南, 诊疗规范, 解读

Abstract: The European Confederation for Medical Mycology, the International Society of Human and Animal Mycology, and the American Society for Microbiology jointly issued Global Guideline for the Diagnosis and Management of Candidiasis in February 2025. Based on high-quality evidence and expert consensus, this guideline systematically elaborates optimal strategies for diagnosing and managing candidiasis, with core contents including: risk stratification and sex-based differences, updates in etiology and species distribution shifts, multidimensional analysis of clinical manifestations, tiered recommendations for diagnostic techniques, stepwise disease management pathways, and graded prevention and control strategies. This article provides an in-depth interpretation of key aspects related to oral candidiasis within the guideline, integrating recent research advances for analysis and discussion. We aim to deliver evidence-based clinical guidance for oral healthcare practitioners and advance the standardization of diagnosis and treatment standards for oral candidiasis in China.

Key words: Candidiasis, oral, guideline, diagnostic and therapeutic standards, interpretation

刘志盈, 杨津, 周红梅. 2025全球念珠菌病诊断与管理指南:口腔临床实践核心要点解读[J]. 口腔医学研究, 2026, 42(3): 179-185.

LIU Zhiying, YANG Jin, ZHOU Hongmei. 2025 Global Guideline for the Diagnosis and Management of Candidiasis: Interpretation of Core Points for Oral Clinical Practice[J]. Journal of Oral Science Research, 2026, 42(3): 179-185.

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2025全球念珠菌病诊断与管理指南:口腔临床实践核心要点解读

2025 Global Guideline for the Diagnosis and Management of Candidiasis: Interpretation of Core Points for Oral Clinical Practice

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