橙皮苷、柠檬烯及茶多酚清除自由基能力的对比研究

口腔医学研究 ›› 2015, Vol. 31 ›› Issue (1): 11-14.

橙皮苷、柠檬烯及茶多酚清除自由基能力的对比研究

刘雅丽,陈思佳,张晨,张向宇^*

天津医科大学口腔医学院口腔预防医学教研室天津 300070

收稿日期:2014-05-22 出版日期:2015-01-28 发布日期:2016-04-29
通讯作者: 张向宇,电话:022-23332102
作者简介:刘雅丽(1988~ ),女,天津人,硕士研究生,主要从事儿童口腔及预防口腔临床及基础的研究工作。
基金资助:
天津市应用基础及前沿技术研究计划(10JCYBJCI3600);天津市高等学校科技发展基金计划(20100133)

Capacity of Hesperidin, Limonene and Tea Polyphenols on Sequestering Free Radical.

LIU Ya-li, CHEN Si-jia, ZHANG Chen, et al

Department of Preventive Dentistry, Stomatological Hospital, Tianjin Medical University, Tianjin 300070

Received:2014-05-22 Online:2015-01-28 Published:2016-04-29

摘要/Abstract

摘要： 目的:研究橙皮苷、柠檬烯及茶多酚对1,1-二苯基-2-三硝基苯肼自由基( DPPH·) 和羟基自由基(·OH)的清除能力。方法:UV-Vis光谱分析方法测定3种天然产物对DPPH·和·OH自由基的清除作用。结果:3种天然产物在实验浓度范围内,对两种自由基均有清除作用,清除效果随浓度增大而增加。橙皮苷(IC₅₀=0.097,0.011)清除DPPH·和·OH的能力明显强于柠檬烯(IC₅₀=0.0024,0.0004)、茶多酚(IC₅₀=0.0144,0.009)。结论:橙皮苷比茶多酚、柠檬烯清除DPPH·和·OH的能力强。

关键词: 橙皮苷, 茶多酚, 柠檬烯, 自由基

Abstract: Objective: To study the capacity of hesperidin, limonene and tea polyphenols on sequestering 1, 1 diphenyl-2-trinitrobenzene hydrazine (DPPH·) and hydroxyl free radical (·OH) . Methods: UV-Vis spectrum analysis method was used to determinate the three natural products on DPPH· and ·OH free radical scavenging. Results: The three natural products in the experimental concentration range have the capacity to remove the free radicals, the removal of effect increases with the concentration. The capacity of hesperidin (IC₅₀=0.097, 0.011) is stronger than the limonene (IC₅₀=0.00236, 0.0004), tea polyphenol (IC₅₀=0.0144, 0.0009) on DPPH· and ·OH scavenging. Conclusion: The antioxidant capacity of hesperidin is stronger than tea polyphenol and limonene in vitro.

Key words: Hesperidin , Tea-polyphenols, Limonene , Free radical

中图分类号:

R780.1

刘雅丽,陈思佳,张晨,张向宇. 橙皮苷、柠檬烯及茶多酚清除自由基能力的对比研究[J]. 口腔医学研究, 2015, 31(1): 11-14.

LIU Ya-li, CHEN Si-jia, ZHANG Chen, et al. Capacity of Hesperidin, Limonene and Tea Polyphenols on Sequestering Free Radical.[J]. Journal of Oral Science Research, 2015, 31(1): 11-14.

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