口腔医学研究

口腔医学研究 ›› 2024, Vol. 40 ›› Issue (10): 938-940.DOI: 10.13701/j.cnki.kqyxyj.2024.10.018

• 研究生病例精粹——口腔黏膜病系列(10) • 上一篇    

以下唇结节为首发表现的梅毒1例

王芳1,2, 粟缀孜1,3, 周刚1,3*   

  1. 1.口颌系统重建与再生全国重点实验室,口腔生物医学教育部重点实验室,口腔医学湖北省重点实验室,武汉大学口腔医(学)院; 湖北 武汉 430079;
    2.武汉大学口腔医院光谷院区牙及牙周疾病诊疗中心 湖北 武汉 430074;
    3.武汉大学口腔医院口腔黏膜科 湖北 武汉 430079
  • 收稿日期:2024-08-26 出版日期:2024-10-28 发布日期:2024-10-24
  • 通讯作者: *周刚,E-mail:zhougang@whu.eud.cn
  • 作者简介:王芳(1992~),山西平遥人,副主任医师,研究方向:口腔黏膜病学,口腔扁平苔藓发病机制。

Nodule on Lower Lip Presented as First Sign of Syphilis: A Case Report

WANG Fang1,2, SU Zhuizi1,3, ZHOU Gang1,3*   

  1. 1. State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan 430079, China;
    2. Center for Cariology, Endodontics and Periodontics, Optics Valley Branch, School & Hospital of Stomatology, Wuhan University, Wuhan 430074, China;
    3. Department of Oral Medicine, School & Hospital of Stomatology, Wuhan University, Wuhan 430079, China
  • Received:2024-08-26 Online:2024-10-28 Published:2024-10-24

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摘要： 梅毒是以性接触为主要传播途径的传染性疾病。一期梅毒的口腔损害形态多样且缺乏特异性,易被误诊。青霉素是治疗梅毒的首选药物,部分患者对青霉素有过敏反应等问题,在临床应用中存在一定限制。本文报道1例以下唇结节为首发表现且对青霉素过敏的梅毒病例,使用多西环素治疗取得较好疗效,旨在强调梅毒的早发现、早诊断、早治疗。

关键词: 梅毒, 硬下疳, 青霉素, 多西环素

Abstract: Syphilis is an infectious disease mainly transmitted through sexual contact. The oral damage of early syphilis is varied, which is easy to be misdiagnosed. Penicillin is the first choice for the treatment of syphilis, but some patients have allergic reactions or other problems, which puts a lot of limitations on the use of it. This article reports a case of syphilis with a nodule as the first sign on the lower lip with penicillin allergy and, who was treated by doxycycline with good effect, aiming to emphasize early detection, diagnosis and treatment of syphilis.

Key words: syphilis, chancre, penicillin, doxycycline