口腔医学研究

口腔医学研究 ›› 2018, Vol. 34 ›› Issue (10): 1081-1084.DOI: 10.13701/j.cnki.kqyxyj.2018.10.012

• 牙周病学研究 • 上一篇    下一篇

维持性血液透析患者牙周健康状况调查及分析

李晓丽1, 崔专2, 丁芳1*   

  1. 1. 首都医科大学附属北京安贞医院口腔科 北京 100029;
    2. 北京大学第三医院肾内科 北京 100191
  • 收稿日期:2018-04-19 出版日期:2018-10-28 发布日期:2018-10-24
  • 通讯作者: 丁芳,电话:(010)64456076
  • 作者简介:李晓丽(1976~ ),女,山西人,主治医师,硕士,主要从事牙周病学研究工作。

Investigation and Analysis of Periodontal Health in Maintenance Hemodialysis Patients.

LI Xiao-li1, CUI Zhuan2, DING Fang1*.   

  1. 1. Department of Oral, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China;
    2. Department Nephrology, Peking University Third Hospital, Beijing 100191, China.
  • Received:2018-04-19 Online:2018-10-28 Published:2018-10-24

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摘要： 目的: 通过调查维持性血液透析患者牙周健康状况,为血液透析患者的牙周疾病提供有效的治疗与预防依据。方法: 选取2017年6月~2018年2月在北京大学第三医院透析中心进行维持性血液透析治疗的1143例患者为研究对象。检查其牙周健康状况,并根据牙周病严重程度分为轻度牙周病组(A组,368例)和中、重度牙周病组(B组,567例)。采用单因素及多因素分析影响维持性血液透析患者牙周病加重的危险因素。结果: 本研究1143例维持性血液透析患者中,牙周健康者208例(18.20%)、轻度牙周病患者368例(32.20%),中度牙周病患者392例(34.30%),重度牙周病患者175例(15.30%)。单因素分析结果显示两组患者在体重、吸烟、口腔定期护理、每日刷牙次数、每次刷牙时长、是否合并糖尿病、透析时间、透析频率以及白蛋白水平方面比较,差异具有统计学意义(P<0.05)。进一步进行多因素分析显示透析时间、透析频率以及合并糖尿病是维持性血液透析患者牙周病加重的危险因素(P<0.05)。结论: 维持性血液透析患者均患有不同程度的牙周病,对于透析时间较长、透析频率频繁以及合并糖尿病患者应密切注意,对患者的牙周卫生给予合理指导,避免其牙周病病情加重。

关键词: 维持性血液透析, 危险因素, 牙周健康状况

Abstract: Objective: To investigate the periodontal health status of maintenance hemodialysis patients, to provide effective treatment, and to prevent basis to periodontal disease in hemodialysis patients. Methods: A total of 1143 patients undergoing maintenance hemodialysis at the Dialysis Center of the Third Hospital of Peking University from June 2017 to February 2018 were selected as study subjects. The periodontal health status was examined and divided into mild periodontal disease group (Group A, 368 cases) and moderate and severe periodontal disease group (Group B, 567 cases) according to the severity of periodontal disease. Univariate and multivariate analysis were used to determine the risk factors for periodontal disease in maintenance hemodialysis patients. Results: Of the 1143 maintenance hemodialysis patients in this study, 208 (18.20%) had good periodontal health, 368 (32.20%) had mild periodontal disease, 392 (34.30%) had moderate periodontal disease, and 175 (15.30%) patients with severe periodontal disease. Univariate analysis showed a statistically significant difference between the two groups in terms of body weight, smoking, regular oral care, daily brushing, length of brushing, diabetes mellitus, dialysis time, dialysis frequency, and albumin levels (P<0.05). Further multivariate analysis showed that the duration of dialysis, frequency of dialysis, and diabetes mellitus were risk factors for increased periodontal disease in maintenance hemodialysis patients (P<0.05). Conclusion: Maintenance hemodialysis patients have varying degrees of periodontal disease. For patients with longer dialysis time, frequent dialysis and patients with diabetes should pay close attention to maintenance hemodialysis patients. The doctor should provide reasonable guidance for the periodontal hygiene of patients and avoid increasing periodontal disease conditions.

Key words: Maintenance hemodialysis, Risk factors, Periodontal health status