口腔医学研究

口腔医学研究 ›› 2023, Vol. 39 ›› Issue (1): 52-55.DOI: 10.13701/j.cnki.kqyxyj.2023.01.010

• 口腔颌面外科学研究 • 上一篇    下一篇

复方甘菊利多卡因凝胶在干槽症治疗中的临床应用

马兆峰1, 侯可贵1, 李石2*   

  1. 1.北京市顺义区医院口腔科 北京 101300;
    2.解放军总医院第七医学中心口腔科 北京 100700
  • 收稿日期:2022-11-15 发布日期:2023-01-28
  • 通讯作者: *李石,E-mail:dentist0709@126.com
  • 作者简介:马兆峰(1977~ ),男,内蒙古赤峰市人,博士,主任医师,研究方向:口腔外科、口腔种植。

Clinical Application of Compound Chamomile Lidocaine Gel in the Treatment of Dry Socket

MA Zhaofeng1, HOU Kegui1, LI Shi2*   

  1. 1. Department of Stomatology, Shunyi District Hospital, Beijing 101300, China;
    2. Department of Stomatology, Seventh Medical Center of PLA General Hospital, Beijing 100700, China
  • Received:2022-11-15 Published:2023-01-28

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摘要： 目的:评价常规治疗基础上联合复方甘菊利多卡因凝胶(商品名:甘美达凝胶)对缓解干槽症患者早期疼痛和促进拔牙创愈合的临床效果。方法:纳入2018年12月~2020年12月在北京市顺义区医院口腔科因干槽症而就诊的病例80例,随机分为观察组和对照组,各40例。观察组牙槽窝在双氧水、生理盐水擦拭后,均匀涂布甘美达凝胶,再填塞碘仿纱条;对照组在擦拭后的牙槽窝内仅填塞碘仿纱条。评估两组患者治疗后第1、3、7天时的疼痛减轻程度[视觉模拟评分法(VAS评分)],治疗后第1、3、7、14天肉芽组织形成状态(拔牙窝内肉芽组织生成量)及干槽症病程时长对比。结果:两组基线数据无显著性差异(P＞0.05);观察组早期(治疗后1 d和3 d)疼痛VAS评分显著低于对照组 (P<0.05);观察组3 d和7 d肉芽组织再生评分显著低于对照组(P<0.05);观察组干槽症病程时间明显短于对照组(P＜0.05)。结论:在干槽症治疗中,采用甘美达凝胶联合碘仿纱条填塞治疗,可明显缓解干槽症患者早期疼痛不适,加速创面的愈合,减短病程时间,因而值得临床医师参考借鉴。

关键词: 干槽症, 复方甘菊利多卡因凝胶, 治疗

Abstract: Objective: To evaluate the clinical efficacy of a combination of conventional treatment and compound chamomile lidocaine gel (Kamistad gel) on relieving early pain and promoting healing of extracted teeth in patients with dry socket. Methods: Eighty cases who visited the Department of Stomatology, Shunyi District Hospital of Beijing from December 2018 to December 2020 due to the occurrence of dry socket were included and randomly divided into observation and control groups, with 40 cases each. In the observation group, after wiped with hydrogen peroxide and normal saline, the alveolar fossa was evenly coated with kamistad gel and then filled with iodoform yarn strips. The control group was filled with only iodoform yarn strips after wiping. The degree of pain reduction (VAS score) on day 1, 3, and 7 after treatment, the amount of granulation tissue production within extraction sockets on day 1, 3, 7, and 14 after treatment, and the length of the disease course of dry socket were evaluated in both groups. Results: There was no significant difference in baseline between two groups (P>0.05). The VAS score of pain in the observation group was significantly lower than that in the control group in the early stage (day 1 and 3 after treatment) (P<0.05). The score of granulation tissue regeneration in the observation group was significantly lower than that in the control group at 3 and 7 days (P<0.05). The duration of dry socket in the observation group was significantly shorter than that in the control group (P<0.05). Conclusion: Kamistad gel combined with iodoform yarn strips can significantly relieve the early pain and discomfort of patients with dry socket, accelerate wound healing, and shorten the duration of the disease.

Key words: dry socket, chamomile lidocaine gel, therapy