口腔医学研究 ›› 2024, Vol. 40 ›› Issue (1): 6-10.DOI: 10.13701/j.cnki.kqyxyj.2024.01.002

• 综述 • 上一篇    下一篇

防治儿童口腔黏膜炎的临床研究

郭锦材1,2, 周红慧2,3*   

  1. 1.长沙市口腔医院药剂科 湖南 长沙 410006;
    2.湖南中医药大学口腔医学院 湖南 长沙 410006;
    3.长沙市口腔医院护理部 湖南 长沙 410006
  • 收稿日期:2023-07-11 出版日期:2024-01-28 发布日期:2024-01-22
  • 通讯作者: *周红慧, E-mail:781432317@qq.com
  • 作者简介:郭锦材(1987~ ),男,湖南桂东人,硕士,副主任药师,研究方向:口腔循证医学研究。
  • 基金资助:
    湖南省自然科学基金(编号:2021JJ70062)湖南省卫生健康委科研计划项目(编号:D202313048136)湖南省中医药科研课题(编号:B2023048)湖南中医药大学校院联合基金项目(编号:2022XYLH123和2022XYLH134)

Clinical Study on Prevention and Treatment of Oral Mucositis in Children

GUO Jincai1,2, ZHOU Honghui2,3*   

  1. 1. Department of Pharmacy, Changsha Stomatological Hospital, Changsha 410006, China;
    2. School of Stomatology, Hunan University of Chinese Medicine, Changsha 410006, China;
    3. Department of Nursing,Changsha Stomatological Hospital, Changsha 410006, China
  • Received:2023-07-11 Online:2024-01-28 Published:2024-01-22

摘要: 儿童口腔黏膜炎是儿科肿瘤患者在化疗、放疗等治疗后常见的并发症,具有发病率高、防治棘手等特点。近年来学者们对防治儿童口腔黏膜炎方法的安全性和有效性开展了临床研究,如帕利夫明、重组人粒细胞巨噬细胞刺激因子、激光、光动力、冷冻疗法、过饱和磷酸钙含漱液、氯己定含漱液、Mucosamin喷雾剂、聚普瑞锌海藻酸钠悬浮液、蜂蜜、维生素E等。本文就防治儿童口腔黏膜炎的临床研究做一综述,以期为儿童口腔黏膜炎的防治和临床研究提供参考。

关键词: 口腔黏膜炎, 儿童, 防治, 临床研究

Abstract: Oral mucositis is a common complication in pediatric oncology patients after chemotherapy and radiotherapy treatments, which is characterized by high incidence and tricky prevention and treatment. In recent years, scholars have conducted clinical studies on the safety and efficacy of some methods to prevent and treat oral mucositis in children, such as palifermin, laser, photodynamic therapy, cryotherapy, supersaturated calcium phosphate, chlorhexidine, mucosamin spray, polaprezinc zinc-L-carnosine, honey, and vitamin E. This paper presents a review of clinical studies on the prevention and treatment of oral mucositis in children, with the aim to provide reference for the prevention and treatment of oral mucositis in children.

Key words: oral mucositis, children, prevention and treatment, clinical study