口腔医学研究

口腔医学研究 ›› 2024, Vol. 40 ›› Issue (3): 233-235.DOI: 10.13701/j.cnki.kqyxyj.2024.03.008

• 口腔预防医学研究 • 上一篇    下一篇

富硒小麦草牙膏对控制牙菌斑和减轻牙龈炎效果的临床研究

皮小琴1,2, 朱彬1,2, 童国勇1,2, 李森森1,2, 赵国栋3, 张怡婷3, 杨再波1,2*   

  1. 1.恩施土家族苗族自治州中心医院口腔诊疗中心 湖北 恩施 445002;
    2.武汉大学恩施临床学院 湖北 恩施 445002;
    3.湖北医药学院 湖北 十堰 442000
  • 收稿日期:2023-09-19 出版日期:2024-03-28 发布日期:2024-03-25
  • 通讯作者: * 杨再波,E-mail: YangZB73@163.com
  • 作者简介:皮小琴(1992~ ),女,湖北恩施人,硕士,主治医师,研究方向:口腔预防医学。
  • 基金资助:
    2023年湖北省自然科学基金联合基金(编号:2023AFD073)

Clinical Study on Effect of Selenium-enriched Wheat Grass Toothpaste on Reducing Gingival Inflammation and Controlling Dental Plaque

PI Xiaoqin1,2, ZHU Bin1,2, TONG Guoyong1,2, LI Sensen1,2, ZHAO Guodong3, ZHANG Yiting3, YANG Zaibo1,2*   

  1. 1. Department of Stomatology, The Central Hospital of Enshi TuJia and Miao Autonomous Prefecture, Enshi 445002, China;
    2. Enshi Clinical College, Wuhan University. Enshi 445002, China;
    3. Hubei University of Medicine. Shiyan 442000, China
  • Received:2023-09-19 Online:2024-03-28 Published:2024-03-25

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摘要： 目的:探讨富硒小麦草牙膏减轻牙龈炎症及控制牙菌斑作用的临床效果。方法:本临床试验遵守随机、对照、双盲的设计原则,按纳入和排除标准将年龄18~65岁间的72例受试者随机分成试验组和对照组,试验组使用富硒小麦草牙膏,对照组使用不含富硒小麦草其余成分完全相同的牙膏,分别在基线、1、3和6个月采用改良Loe-Silness牙龈指数、龈沟出血指数和改良Quigley-Hein菌斑指数评价牙周状况。结果:1、3和6个月时,牙龈指数试验组对照组均数计分分别为1.16±0.10和1.26±0.22,0.99±0.91和1.21±1.16,0.92±0.11和1.01±0.11;龈沟出血指数试验组对照组均数计分分别为1.12±0.23和1.24±0.27,1.05±0.11和1.13±0.15,0.91±0.12和1.05±0.09;牙菌斑指数试验组对照组均数计分分别为1.37±0.20和1.54±0.19,1.14±0.21和1.37±0.24,0.98±0.16和1.21±0.22,3个月和6个月时比较,差异有统计学意义(P<0.05)。说明其具有抑制牙菌斑和促进牙龈健康的作用。在本临床研究中未观察到不良反应,验证了富硒小麦草牙膏的安全性。结论:本研究提示富硒小麦草牙膏可以明显控制牙菌斑的形成,促进牙龈健康。

关键词: 富硒小麦草, 牙膏, 牙龈炎症, 牙菌斑

Abstract: Objective: To investigate the clinical impact of toothpaste enriched with selenium-rich wheat grass. Methods: Following the principles of randomized, double-blind, controlled design, 72 participants aged 18 to 65 years were randomly assigned to either the experimental group (using selenium-rich wheat grass toothpaste) or the control group (using no selenium-rich wheat grass toothpaste). The gingival index, gingival bleeding index, and plaque index were evaluated at baseline, 1 month, 3 months, and 6 months after treatment. Results: At 1,3 and 6 months,the mean scores of gingival index in experimental group and control group were 1.16±0.10 and 1.26±0.22, 0.99±0.91 and 1.21±1.16, 0.92±0.11 and 1.01±0.11, respectively. The mean scores of gingival sulcus bleeding index in the experimental group and control group were 1.12±0.23 and 1.24±0.27, 1.05±0.11 and 1.13±0.15, 0.91±0.12 and 1.05±0.09, respectively. The mean scores of plaque index in the experimental group and control group were 1.37±0.20 and 1.54±0.19, 1.14±0.21 and 1.37±0.24, 0.98±0.16 and 1.21±0.22, respectively. Notably, no adverse effects were observed during this clinical study. Conclusion: Selenium-enriched wheat grass toothpaste significantly hampers dental plaque formation, alleviates gingivitis, and enhances gum health.

Key words: selenium-rich wheat grass toothpaste, gingival inflammation, dental plaque