口腔医学研究

口腔医学研究 ›› 2016, Vol. 32 ›› Issue (12): 1269-1272.DOI: 10.13701/j.cnki.kqyxyj.2016.12.011

• 临床研究论著 • 上一篇    下一篇

GTR联合植骨术在显微根尖外科手术中应用的临床观察

陈瑶1,申静2*   

  1. 1. 南开大学医学院 天津 300071;
    2. 天津市口腔医院国际诊疗中心 天津 300041
  • 收稿日期:2016-06-20 出版日期:2016-12-25 发布日期:2016-12-26
  • 通讯作者: 申静,电话:13820140975
  • 作者简介:陈瑶(1990~ ),女,安徽池州人,硕士,主要从事根尖周病的临床及基础研究。
  • 基金资助:
    天津市自然科学基金项目(编号:11JCYBJC11900)

Clinical Observation of GTR Combined with Bone Grafting in Endodontic Microsurgery.

CHEN Yao1, SHEN Jing2*.   

  1. 1. Medical College of Naikai University, Tianjin 300071, China;
    2. International Clinic Center, Stomatological Hospital of Nankai University, Stomatological Hospital of Tianjin, Tianjin 300041, China
  • Received:2016-06-20 Online:2016-12-25 Published:2016-12-26

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被引次数

3

摘要： 目的:评价引导组织再生术(Guide Tissue Regeneration,GTR)联合植骨术应用于显微根尖外科手术中治疗大范围持续性根尖周病的临床疗效。方法:将X线片显示根尖病损最大直径大于10 mm的持续性根尖周病患者80例随机分为两组行显微根尖外科手术。其中,实验组术中对根尖骨缺损处植入无机骨粉、覆盖胶原膜,对照组骨腔不做特殊处理。观察两组病例术后半年、1年的临床疗效。结果:实验组术后半年成功率明显高于对照组,差异有统计学意义(P＜0.05);两组术后1年的术后成功率差异无统计学意义。颊、舌侧骨板缺损的病例实验组术后半年、1年成功率均明显高于对照组,差异有统计学意义(P＜0.05)。结论:GTR联合植骨术应用于显微根尖外科手术能明显促进根尖部骨再生,缩短骨腔愈合时间,有利于伴有颊、舌侧骨板缺损的大范围根尖周病变愈合。

关键词: 显微根尖手术, 引导组织再生术, 胶原膜, 无机骨粉

Abstract: Objective: To evaluate the effects of endodontic microsurgery in large persistent periapical lesions combined with guided tissue regeneration (GTR) and anorganic bovine bone. Methods: A total of eighty patients with persistent apical periodontitis (≥10 mm in periapical radiographs) were included and randomly grouped into two groups. During the endodontic microsurgery, the defect in the test group was filled with anorganic bovine bone and covered by resorbable collagen membrane. In the control group, neither graft nor membrane was used. Six months and one year later, the clinical index was recorded. Results: The success rate of the experimental group was significantly higher than that of the control group after 6 months (P＜0.05), while the difference was not statistically significant after one year. There was no significant difference in the success rate after 6 months, when the lesion had a perforated palatal/lingual cortical plate. However, the difference was statistically significant after one year (P＜0.05). Conclusion: GTR combined with anorganic bovine bone can significantly promote the regeneration of the bone and reduce the healing time, which is beneficial to the healing of the large periapical lesion with a perforated palatal/lingual cortical plate.

Key words: Endodontic microsurgery, Guide tissue regeneration, Collagen membrane, Anorganic bovine bone

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