口腔医学研究

口腔医学研究 ›› 2016, Vol. 32 ›› Issue (9): 941-943.DOI: 10.13701/j.cnki.kqyxyj.2016.09.012

• 临床研究论著 • 上一篇    下一篇

头颈部侵袭性纤维瘤病的治疗

曹俊,孙国文*,朱锋   

  1. 南京大学医学院附属口腔医院颌面外科 江苏 南京 210008
  • 收稿日期:2015-11-09 出版日期:2016-09-26 发布日期:2016-09-26
  • 通讯作者: 孙国文,电话:025-83620326
  • 作者简介:曹俊(1984~ ),男,江苏人,硕士,主治医师,主要从事口腔颌面外科临床治疗工作。
  • 基金资助:
    江苏省临床医学科技专项项目(编号:BL2012017,BL2013005)
    江苏省卫生厅课题项目(编号:H201441)

Treatment of Aggressive Fibromatosis in Head and Neck Region

CAO Jun, SUN Guo-wen*, ZHU Feng   

  1. Department of Oral and Maxillofacial Surgery, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing 210008, China
  • Received:2015-11-09 Online:2016-09-26 Published:2016-09-26

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摘要： 目的:评估头颈部侵袭性纤维瘤病的诊断、治疗和预后。方法:对2001~2014年我科手术治疗的头颈部侵袭性纤维瘤病患者作回顾性研究。结果:根据2005年世界卫生组织的诊断标准,本文共报道了9例头颈部侵袭性纤维瘤病患者,随访至今6例未见复发,3例复发。结论:头颈部结构复杂,手术操作空间有限,推荐切除安全边界为0.5~1 cm。对于能够手术完整切除的病例,术后随访结果较为满意,但肿瘤复发的可能性仍存在;对于肿瘤邻近重要解剖结构无法完整切除者,推荐肿瘤部分切除结合术后放疗。远期治疗效果仍需要进一步随访、观察。

关键词: 侵袭性纤维瘤病, 局部扩大切除, 放疗

Abstract: Objective: To evaluate the diagnosis, treatment and prognosis of aggressive fibromatosis in head and neck region. Methods: Patients with aggressive fibromatosis in head and neck region from 2001 to 2014 were treated by operation and retrospectively studied in our department. Results: According to the diagnostic criteria of WHO in 2005, 9 cases of patients with aggressive fibromatosis occurred in head and neck region. So far, 3 cases relapsed. Conclusion: The head and neck structures were complex and operation space was limited. The recommended safe margin was 0.5~1 cm. For patients with complete resection, the prognosis was satisfactory, but tumor recurrence might still exist. If the lesions were adjacent to the important anatomic structure, partial resection combined with postoperative radiotherapy was suggested, and the long-term curative effect needed to be further investigated.

Key words: Aggressive fibromatosis, Extended resection, Radiotherapy

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