雌激素影响牙周组织机制的研究进展

doi:10.13701/j.cnki.kqyxyj.2019.10.005

摘要/Abstract

摘要： 牙周组织中雌激素受体的发现是雌激素可以对其发挥作用的直接证据。目前研究认为,雌激素可以调节机体的固有免疫和适应性免疫。雌激素对牙槽骨有保护作用,而雌激素缺乏与牙槽骨密度的降低和牙齿缺失可能有关。雌激素对牙周膜干细胞的功能也有影响。探索雌激素对牙周组织影响的机制有助于进一步明确牙周病的发病机制,同时对预防和治疗雌激素相关的牙周疾病也具有重要意义。

关键词: 雌激素, 牙周组织, 免疫系统, 牙槽骨

Abstract: The discovery of estrogen receptors in periodontal tissue provides direct evidence that estrogen is associated with periodontal health. Current studies also show that estrogen has effect on both innate immunity and adaptive immunity. Estrogen is protective on alveolar bone, and estrogen deficiency may lead to decrease of alveolar bone density and teeth loss. Estrogen can also influence the function of periodontal ligament stem cells. Exploring the mechanism of estrogen on periodontal tissues is helpful for further clarifying the pathogenesis of periodontal diseases, and it is beneficial to the prevention and treatment of estrogen-related periodontal diseases as well.

Key words: estrogen, periodontal tissue, immune system, alveolar bone

李治邦, 李琨. 雌激素影响牙周组织机制的研究进展[J]. 口腔医学研究, 2019, 35(10): 928-930.

LI Zhibang, LI Kun. Progress on Mechanism for the Effect of Estrogen on Periodontal Tissues[J]. Journal of Oral Science Research, 2019, 35(10): 928-930.

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