乳牙盖髓剂MTA与新型生物材料Biodentine的比较

doi:10.13701/j.cnki.kqyxyj.2021.01.005

摘要/Abstract

摘要： 目前,牙髓切断术是最常见的乳牙牙髓治疗方法之一,该治疗方法在严格无菌条件下,去除冠部感染牙髓并用盖髓剂覆盖于健康牙髓断面上,达到保留健康活髓的目的。尽管矿物质三氧化物聚集体(MTA)是乳牙牙髓切断术的常用盖髓剂,但其仍有许多缺点。近年出现的新型硅酸钙材料Biodentine(BD)有着优良的机械性能、生物相容性和较好的临床疗效,有望成为MTA的替代品。本文比较了BD和MTA作为盖髓剂的各方面性能及临床疗效等,从而探讨新型材料BD作为乳牙牙髓切断术盖髓剂的应用前景。

关键词: 乳牙, 活髓切断剂, 硅酸盐, 矿物质三氧化物聚集体, Biodentine

Abstract: Pulpotomy is one of the most common therapies of primary teeth. The pulpotomy technique involves a series of sterile procedures including removal of the infected pulp and covering the remaining pulp with a pulp-capping agent. Mineral trioxide aggregate (MTA) is now commonly used as pulp-capping agent for pulpotomies in primary teeth, but it still has many disadvantages. Biodentine (BD), a new-developed calcium silicate cement with superior mechanical property, biocompatibility, and excellent clinical effect, is a promising alternative to MTA. In this review, we list and compare the characteristics and clinical efficacy of MTA with BD as pulpotomy agents for primary teeth.

Key words: primary teeth, pulpotomy agents, silicates, mineral trioxide aggregate, Biodentine

麦丽嘉, 袁国华. 乳牙盖髓剂MTA与新型生物材料Biodentine的比较[J]. 口腔医学研究, 2021, 37(1): 19-22.

MAI Lijia, YUAN Guohua. Comparison of Biodentine and MTA as Pulpotomy Agents for Primary Teeth[J]. Journal of Oral Science Research, 2021, 37(1): 19-22.

参考文献

[1] Pulp therapy for primary and immature permanent teeth [J]. Pediatr Dent, 2018, 40(6):343-351.
[2] Qureshi A, E S, Nandakumar, et al. Recent advances in pulp capping materials: an overview [J]. J Clin Diagn Res, 2014, 8(1):316-321.
[3] 汪俊. 乳牙牙髓病及根尖周病的治疗[J].中华口腔医学杂志,2019,54(5): 356-359.
[4] Guideline on pulp therapy for primary and immature permanent teeth [J]. Pediatr Dent, 2016, 38(6): 280-288.
[5] Parirokh M, Torabinejad M. Mineral trioxide aggregate: a comprehensive literature review--Part Ⅲ : Clinical applications, drawbacks, and mechanism of action[J]. J Endod, 2010, 36(3): 400-413.
[6] Rajasekharan S, Martens LC, Cauwels RG,et al. Biodentine^TM material characteristics and clinical applications: a review of the literature[J].Eur Arch Paediatr Dent, 2014, 15(3):147-158.
[7] Rajasekharan S, Martens LC, Cauwels RG,et al. Biodentine^TM material characteristics and clinical applications: A three year literature review update[J].Eur Arch Paediatr Dent, 2018, 19(1): 1-22.
[8] Prati C, Gandolfi MG. Calcium silicate bioactive cements: Biological perspectives and clinical applications [J]. Dent Mater, 2015, 31(4): 351-370.
[9] Tawil PZ, Duggan DJ, Galicia JC. Galicia, Mineral trioxide aggregate (MTA): its history, composition, and clinical applications [J]. Compend Contin Educ Dent, 2015, 36(4): 247-252.
[10] Kaur M, Singh H, Dhillon JS, et al. MTA versus biodentine: review of literature with a comparative analysis [J]. J Clin Diagn Res, 2017, 11(8):ZG01-ZG05.
[11] Grech L, Mallia B, Camilleri J. Investigation of the physical properties of tricalcium silicate cement-based root-end filling materials [J]. Dent Mater, 2013, 29(2): e20-e28.
[12] Noh YS, Chung SH, Bae KS, et al. Mechanical properties and microstructure analysis of mineral trioxide aggregate mixed with hydrophilic synthetic polymer [J]. J Biomed Mater Res B Appl Biomater, 2015, 103(4): 777-782.
[13] Aggarwal V, Singla M, Miglani S, et al. Comparative evaluation of push-out bond strength of ProRoot MTA, Biodentine, and MTA Plus in furcation perforation repair [J]. J Conserv Dent, 2013, 16(5): 462-465.
[14] Coomaraswamy KS, Lumley PJ, Hofmann MP. Effect of bismuth oxide radioopacifier content on the material properties of an endodontic Portland cement-based (MTA-like) system [J]. J Endod, 2007, 33(3): 295-298.
[15] Butt N, Talwar S, Chaudhry S, et al. Comparison of physical and mechanical properties of mineral trioxide aggregate and Biodentine [J]. Indian J Dent Res, 2014, 25(6): 692-697.
[16] Subramanyam D, Vasantharajan M. Effect of oral tissue fluids on compressive strength of MTA and biodentine: an in vitro study [J]. J Clin Diagn Res, 2017, 11(4): ZC94-ZC96.
[17] Majeed A, AlShwaimi E. Push-out bond strength and surface microhardness of calcium silicate-based biomaterials: an in vitro study [J]. Med Princ Pract, 2017, 26(2): 139-145.
[18] Nishikawa Y, Koyama N, Yoshida Y,et al. Activation of ascending antinociceptive system by vagal afferent input as revealed in the nucleus ventralis posteromedialis [J]. Brain Res, 1999, 833(1): 108-111.
[19] Tanalp J, Karapğnar-Kazanda M, Dölekoğlu S, et al. Comparison of the radiopacities of different root-end filling and repair materials [J]. ScientificWorldJournal, 2013, 2013: 594950.
[20] Chang SW, Lee SY, Ann HJ, et al. Effects of calcium silicate endodontic cements on biocompatibility and mineralization-inducing potentials in human dental pulp cells [J]. J Endod, 2014, 40(8): 1194-1200.
[21] Zakerzadeh A, Esnaashari E, Dadfar S. In vitro comparison of cytotoxicity and genotoxicity of three vital pulp capping materials [J]. Iran Endod J, 2017, 12(4): 419-425.
[22] Collado-González M, García-Bernal D, Oñate-Sánchez RE,et al. Cytotoxicity and bioactivity of various pulpotomy materials on stem cells from human exfoliated primary teeth [J]. Int Endod J, 2017, 50 Suppl 2: e19-e30.
[23] Bakhtiar H, Nekoofar MH, Aminishakib P,et al. Human pulp responses to partial pulpotomy treatment with theraCal as compared with biodentine and proRoot MTA: A clinical trial[J]. J Endod, 2017, 43(11):1786-1791.
[24] De Rossi A, Silva LA, Gatón-Hernández P,et al. Comparison of pulpal responses to pulpotomy and pulp capping with biodentine and mineral trioxide aggregate in dogs[J]. J Endod, 2014, 40(9):1362-1369.
[25] Refaei P, Jahromi MZ, Moughari AAK. Comparison of the microleakage of mineral trioxide aggregate, calcium-enriched mixture cement, and Biodentine orthograde apical plug [J]. Dent Res J (Isfahan), 2020, 17(1): 66-72.
[26] Bhavana V, Chaitanya KP, Gandi P, et al. Evaluation of antibacterial and antifungal activity of new calcium-based cement (Biodentine) compared to MTA and glass ionomer cement [J]. J Conserv Dent, 2015, 18(1):44-46.
[27] Fathy SM, Abd El-Aziz AM, Labah DA. Cellular interaction and antibacterial efficacy of two hydraulic calcium silicate-based cements: Cell-dependent model [J]. J Conserv Dent, 2019, 22(1):17-22.
[28] Marciano MA, Estrela C, Mondelli RF, et al. Analysis of the color alteration and radiopacity promoted by bismuth oxide in calcium silicate cement[J]. Braz Oral Res, 2013, 27(4): 318-323.
[29] Marciano MA, Duarte MA, Camilleri J. Dental discoloration caused by bismuth oxide in MTA in the presence of sodium hypochlorite [J]. Clin Oral Investig, 2015, 19(9):2201-2209.
[30] Vallés M, Roig M, Duran-Sindreu F, et al. Color stability of teeth restored with biodentine: a 6-month in vitro study [J]. J Endod, 2015, 41(7):1157-1160.
[31] Stringhini Junior E, Vitcel ME, Oliveira LB. Evidence of pulpotomy in primary teeth comparing MTA, calcium hydroxide, ferric sulphate, and electrosurgery with formocresol [J]. Eur Arch Paediatr Dent, 2015, 16(4): 303-312.
[32] Cuadros-Fernández C, Lorente Rodríguez AI, Sáez-Martínez S,et al. Short-term treatment outcome of pulpotomies in primary molars using mineral trioxide aggregate and Biodentine: a randomized clinical trial [J]. Clin Oral Investig, 2016, 20(7):1639-1645.
[33] Borkar SA, Ataide I. Biodentine pulpotomy several days after pulp exposure: Four case reports [J]. J Conserv Dent, 2015, 18(1): 73-78.
[34] Hegde R, Battepati PM. Clinical applications of mineral trioxide aggregate: report of four cases [J]. Int J Clin Pediatr Dent, 2010, 3(1): 43-50.
[35] Nagendrababu V, Pulikkotil SJ, Veettil SK, et al. Efficacy of biodentine and mineral trioxide aggregate in primary molar pulpotomies-a systematic review and meta-analysis with trial sequential analysis of randomized clinical trials [J]. J Evid Based Dent Pract, 2019, 19(1): 17-27.
[36] Stringhini Junior E, Dos Santos MGC, Oliveira LB, et al. MTA and biodentine for primary teeth pulpotomy: a systematic review and meta-analysis of clinical trials [J]. Clin Oral Investig, 2019, 23(4): 1967-1976.
[37] Shafaee H, Alirezaie M, Rangrazi A, et al. Comparison of the success rate of a bioactive dentin substitute with those of other root restoration materials in pulpotomy of primary teeth: Systematic review and meta-analysis [J]. J Am Dent Assoc, 2019, 150(8): 676-688.
[38] Parirokh M, Torabinejad M, Dummer PMH. Mineral trioxide aggregate and other bioactive endodontic cements: an updated overview-part I: vital pulp therapy [J]. Int Endod J, 2018, 51(2): 177-205.