PLA可吸收根管桩联合氰基丙烯酸酯粘接剂在婴幼儿前牙残冠的临床应用研究

doi:10.13701/j.cnki.kqyxyj.2021.02.010

口腔医学研究 ›› 2021, Vol. 37 ›› Issue (2): 135-138.DOI: 10.13701/j.cnki.kqyxyj.2021.02.010

PLA可吸收根管桩联合氰基丙烯酸酯粘接剂在婴幼儿前牙残冠的临床应用研究

齐凤娜^*, 孙红蕾, 许华, 李军科, 程瑞卿

河北省眼科医院口腔科河北邢台 050000

收稿日期:2020-05-27 发布日期:2021-02-11
通讯作者: 齐凤娜,E-mail:544603802@qq.com
作者简介:齐凤娜(1988~ ),女,硕士,主治医师,研究方向:口腔内科、牙周病学、牙体牙髓、儿童牙病。
基金资助:
河北省医学科学研究课题计划项目(编号:20191046)

Clinical Application of PLA Absorbable Root Canal Post Combined with Cyanoacrylate Adhesive in Residual Crown of Infant Anterior Teeth

QI Fengna^*, SUN Honglei, XU Hua, LI Junke, CHENG Ruiqing

Department of Stomatology, Hebei Eye Hospital, Xingtai 050000, China

Received:2020-05-27 Published:2021-02-11

摘要/Abstract

摘要： 目的:研究聚乳酸(PLA)可吸收根管桩联合氰基丙烯酸酯粘接剂在婴幼儿前牙残冠修复中的应用价值。方法:选取2017年1月~2018年12月我院收治的前牙残冠婴幼儿患者100例,按照完全随机法将所有患儿分为对照组和PLA组各50例。对照组采用玻璃纤维短桩联合双重固化树脂粘接剂修复,PLA组采用PLA可吸收根管桩联合氰基丙烯酸酯粘接剂修复。评价两组患儿牙龈情况、咬合功能、牙龈沟炎症反应、临床疗效,并随访统计不良事件发生情况。结果:两组患儿修复后牙龈指数、咬合力高于修复前,牙龈出血指数低于修复前,且PLA组患儿牙龈指数、咬合力高于对照组,牙龈出血指数低于对照组,差异有统计学意义(P＜0.05)。PLA组修复后牙龈沟炎症指标TNF-α、CRP、IL-8、IL-6表达水平均低于对照组,差异有统计学意义(P＜0.05)。PLA组修复成功率显著高于对照组(P＜0.05),PLA组不良事件总发生率显著低于对照组(P＜0.05)。结论:婴幼儿前牙残冠修复治疗中应用PLA可吸收根管桩联合氰基丙烯酸酯粘接剂可改善牙龈状态,抑制TNF-α、CRP、IL-8、IL-6等炎症因子表达,对牙龈的刺激较小,可降低不良事件的发生,修复成功率较高。

关键词: 聚乳酸可吸收根管桩, 氰基丙烯酸酯粘接剂, 婴幼儿前牙残冠修复

Abstract: Objective: To study the application of polylactic acid (PLA) absorbable root canal post combined with cyanoacrylate adhesive in the restoration of infant anterior crown. Methods: A total of 100 infants with anterior residual crown admitted to our hospital from January 2017 to December 2018 were selected and randomly divided into control group and PLA group with 50 cases each. The control group was repaired with glass fiber short post combined with double curing resin adhesive, while the PLA group was repaired with PLA absorbable root pipe post combined with cyanoacrylate adhesive. The gingival condition, occlusal function, gingival sulcus inflammation, and clinical efficacy of two groups were evaluated, and the incidence of adverse events was followed up. Results: The gingival index and bite force after repair were higher than those before repair, and the gingival bleeding index was lower than that before repair. In addition, the gingival index and bite force of the PLA group were higher than those of the control group, and the gingival bleeding index was lower than that of the control group (P<0.05). After repair, the levels of TNF-α, CRP, IL-8, and IL-6 in the PLA group were all lower than those in the control group (P<0.05). The success rate of repair in PLA group was significantly higher than that in control group (P<0.05). The total incidence of adverse events in PLA group was significantly lower than that in the control group (P<0.05). Conclusion: PLA absorbable root canal post combined with cyanoacrylate adhesive can improve gingival state, inhibit the expression of TNF-α, CRP, IL-8, IL-6, and other inflammatory indexes in the treatment of residual crown of anterior teeth in infants, which has less stimulation to gingiva, reduces the occurrence of adverse events, and has a high success rate of restoration.

Key words: PLA absorbable root canal post, cyanoacrylate adhesive, restoration of residual crown of infant anterior teeth

齐凤娜, 孙红蕾, 许华, 李军科, 程瑞卿. PLA可吸收根管桩联合氰基丙烯酸酯粘接剂在婴幼儿前牙残冠的临床应用研究[J]. 口腔医学研究, 2021, 37(2): 135-138.

QI Fengna, SUN Honglei, XU Hua, LI Junke, CHENG Ruiqing. Clinical Application of PLA Absorbable Root Canal Post Combined with Cyanoacrylate Adhesive in Residual Crown of Infant Anterior Teeth[J]. Journal of Oral Science Research, 2021, 37(2): 135-138.

参考文献

[1] 黄新文,肖小芬,陈华.婴幼儿龋病的危险因素分析[J].广西医学,2015,37(9):1295-1297.
[2] 许耕,王向荣.婴幼儿乳牙萌出延迟的相关因素分析[J].安徽医学,2017,38(8):1039-1041.
[3] 陈爱华,黄华.婴幼儿乳牙残冠残根修复的研究进展[J].国际口腔医学杂志,2013,40(5):600-603.
[4] 张靖.玻璃纤维桩和铸造金属桩在上颌前牙残冠残根修复中的临床对比研究[J].哈尔滨医科大学学报,2016,50(4):377-380.
[5] 黄飞.玻璃纤维桩与铸造金属桩核修复前牙残根残冠的临床疗效对比[J].医学综述,2016,22(9):1833-1835.
[6] Shin DY, Kang MH, Kang IG, et al. In vitro and in vivo evaluation of polylactic acid-based composite with tricalcium phosphate microsphere for enhanced biodegradability and osseointegration [J]. J Biomater Appl, 2018, 32(10):1360-1370.
[7] Yoo KH, Cho HS, Kim DH, et al. Polylactic acid/nanostructured si-substituted β-tricalcium phosphate composites for biodegradable fixation medical devices [J]. J Nanosci Nanotechnol, 2018, 18(2):856-860.
[8] Demyashkin G, Kogan E, Borozdkin L, et al. Immunohistochemical and morphological characteristics of tissues response to polylactic acid membranes with silver nanoparticles [J]. Med Oral Patol Oral Cir Bucal, 2020, 25(1):e29-e33.
[9] 侯玉妹,黄华,周永明.聚乳酸可吸收薄膜对可吸收螺纹桩封闭性能的微渗漏研究[J].牙体牙髓牙周病学杂志,2015,25(10):610-614.
[10] 徐高祥,张鲁鲁,高华丽, 等.不同比例PLLA/PDLLA/5％HA复合物体外降解性能的研究[J].中国实验诊断学,2017,21(6):1067-1071.
[11] Varga N, Hornok V, Janovák L,et al. The effect of synthesis conditions and tunable hydrophilicity on the drug encapsulation capability of PLA and PLGA nanoparticles [J]. Colloids Surf B Biointerfaces, 2019, 176:212-218.
[12] Saghiri MA, Karamifar K, Mehrvazfar P, et al. The efficacy of foam cleaners in removing debris from two endodontic instruments [J]. Quintessence Int, 2012, 43(9):811-817.
[13] 王春燕,张琨,姜松磊.聚乳酸根管桩修复乳牙残根残冠的研究进展[J].国际口腔医学杂志,2018,45(1):74-77.
[14] 赵哲珊,黄华,邱荣敏,等.聚乳酸可吸收根管桩膜生物相容性实验[J].华西口腔医学杂志,2016,34(5):463-467.
[15] 崔国廉,但年华,但卫华,等.基于生物质的医用粘合剂及应用现状与发展前景[J].皮革科学与工程,2015,25(5):33-40.
[16] 王吓勇,杨倞,黄慧芳.两种树脂粘接剂对纤维桩核冠方微渗漏影响的对比研究[J].临床口腔医学杂志,2016,32(7):396-398.

PLA可吸收根管桩联合氰基丙烯酸酯粘接剂在婴幼儿前牙残冠的临床应用研究

Clinical Application of PLA Absorbable Root Canal Post Combined with Cyanoacrylate Adhesive in Residual Crown of Infant Anterior Teeth

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