口腔医学研究

口腔医学研究 ›› 2023, Vol. 39 ›› Issue (11): 978-981.DOI: 10.13701/j.cnki.kqyxyj.2023.11.008

• 口腔影像学研究 • 上一篇    下一篇

颌骨原发性非霍奇金淋巴瘤的临床及CT影像学特征分析

冯永静1, 文珊辉1, 王铁梅1*, 滕跃辉1, 夏舒2   

  1. 1.南京大学医学院附属口腔医院,南京市口腔医院口腔颌面医学影像科 江苏 南京 210008;
    2.南京大学医学院附属口腔医院,南京市口腔医院病理科 江苏省南京 210008
  • 收稿日期:2023-05-22 出版日期:2023-11-28 发布日期:2023-11-22
  • 通讯作者: *王铁梅,E-mail:tiemei106@263.net
  • 作者简介:冯永静(1994~ ),女,安徽阜阳人,硕士,住院医师,研究方向:口腔颌面影像。
  • 基金资助:
    江苏省自然科学基金(编号:BK20150089)江苏省南京市医学科技发展项目(编号:YKK15116)

Clinical and CT Imaging Analysis of Primary Non-Hodgkin Lymphoma of Jaw

FENG Yongjing1, WEN Shanhui1, WANG Tiemei1*, TENG Yuehui1, XIA Shu2   

  1. 1. Department of Radiology, Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing 210008, China;
    2. Department of Pathology, Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing 210008, China
  • Received:2023-05-22 Online:2023-11-28 Published:2023-11-22

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摘要： 目的: 探讨颌骨原发性非霍奇金淋巴瘤的临床及CT影像学特征。方法: 回顾性分析经病理检查证实的颌骨原发性非霍奇金淋巴瘤24例患者临床及CT影像学特征。结果: 24例颌骨原发性非霍奇金淋巴瘤中男17例,女7例。24例中16例患者在确诊前进行过抗炎治疗,6例患者在确诊前有拔牙治疗,2例患者行切开引流。骨质改变影像分型:溶骨型骨质破坏占17/24,混合型骨质破坏占5/24,牙槽骨吸收型占2/24。骨质破坏边缘的分型为:虫蚀型占8/24,浸润型占13/24,地图型占3/24,骨质破坏边缘分型在上下颌骨的不同部位具有明显统计学差异(P=0.003),下颌骨边缘破坏以虫蚀型为主,上颌骨病变边缘破坏以浸润型为主,发生在上下颌骨后部骨质改变溶骨型最多见。结论: 颌骨原发性非霍奇金淋巴瘤具有一定的临床及影像学特征,这有助于对其疾病的临床及影像辨知。

关键词: 颌骨, 原发性非霍奇金淋巴瘤, CT影像学特征, 临床表现

Abstract: Objective: To analyze the clinical and CT imaging features of primary bone non-Hodgkin lymphoma (PB-NHL) of jaw retrospectively. Methods: The clinical and CT imaging features of 24 patients with PB-NHL of jaw confirmed by pathology were retrospectively analyzed. Results: Of the 24 patients with PB-NHL of the jaw, 17 were male and 7 were female; 16 underwent anti-inflammatory therapy before diagnosis, 6 underwent tooth extraction, and 2 underwent incision and drainage. In the imaging classification of bone changes, osteolytic type accounted for 17/24, mixed type accounted for 5/24, and alveolar bone resorption accounted for 2/24. In the classification of the edge of bone destruction, moth-eaten destruction margin accounted for 8/24, infiltration destruction margin accounted for 13/24, and geographic type accounted for 3/24. There was significant statistical difference between different parts of mandible and mandible in the classification of bone destruction margin (P=0.003). Moth-eaten was the main type of mandibular edge damage, and infiltration was the main type of maxillary edge damage. Osteolytic type was the most common bone change in posterior mandible. Conclusion: PB-NHL of the jaw has certain clinical and imaging characteristics, which is helpful for the clinical and imaging recognition of the disease.

Key words: jaw, primary non-hodgkin lymphoma, CT imaging, clinical