口腔医学研究

口腔医学研究 ›› 2023, Vol. 39 ›› Issue (11): 1000-1004.DOI: 10.13701/j.cnki.kqyxyj.2023.11.012

• 口腔修复学研究 • 上一篇    下一篇

聚氨酯低聚物对光固化树脂基质性能的影响

冯丹*, 杨政远, 温雅晴, 林岐   

  1. 吉林大学口腔医院修复科 吉林 长春 130021
  • 收稿日期:2023-06-20 出版日期:2023-11-28 发布日期:2023-11-22
  • 通讯作者: *冯丹,E-mail:fengdudu1989@163.com
  • 作者简介:冯丹(1989~ )女,吉林四平人,博士,主治医师,研究方向:牙科修复材料。
  • 基金资助:
    国家自然科学基金(编号:82071163)吉林省科技厅国际科技合作项目(编号:20220402077GH)

Effect of Poly-urethane Oligomer on Properties of Light-cured Dental Resin

FENG Dan*, YANG Zhengyuan, WEN Yaqing, LIN Qi   

  1. Department of Prosthodontics, School and Hospital of Stomatology, Jilin University, Changchun 130021, China
  • Received:2023-06-20 Online:2023-11-28 Published:2023-11-22

PDF (PC)

52

摘要： 目的: 合成一种聚氨酯-二甲基丙烯酸酯低聚物(PU-MA),应用于牙科可见光固化树脂基质以改善其综合性能。方法: 以BPA、IPDI和HEMA为原料合成PU-MA,并与POSS-MA、Bis-GMA/TEGDMA共混配制新型可见光固化树脂基质,通过物理-机械性能和体外细胞毒性检测,评价其综合性能;采用SPSS20.0统计软件对数据进行单因素和双因素方差分析。结果: 20wt% PU-MA使树脂基质的挠曲强度达(124.51±6.00) MPa,高于ISO 4049要求的下限(≥90 MPa);吸水和溶解值为(25.93±1.47) μg/mm3和(0.50±0.08) μg/mm3,低于ISO 4049要求的上限(吸水值≤40 μg/mm3,溶解值≤7.5 μg/mm3);体外细胞毒性试验表明,L929细胞增殖率大于90%,且细胞生长形态良好。结论: 在一定条件下(对于甲基丙烯酸酯基树脂),PU-MA可有效提高传统树脂基质的力学性能,降低其吸水和溶解性,在改善复合树脂耐老化性能方面可能具有较好的应用潜力。

关键词: 树脂基质, 聚氨酯, 吸水和溶解性, 机械性能

Abstract: Objective: To improve the comprehensive performance of dental resin matrix through a new polyurethane-dimethacrylate oligomer (PU-MA). Methods: BPA, IPDI, and HEMA were used to synthesize the PU-MA, and the new dental resin matrix was prepared by combining the PU-MA with Bis-GMA/TEGDMA resin matrix reinforced by 5 wt% POSS-MA. The mechanical-physical properties and in vitro cytotoxicity were tested. Results: The flexible strength of PU-MA-20 was up to (124.51±6.00) MPa, which was higher than the minimum standard of ISO 4049(≥90 MPa); the water absorption and solubility were (25.93±1.47) μg/mm3 and (0.50±0.08) μg/mm3, which were lower than the maximum standard of ISO 4049(water absorption≤40 μg/mm3, water solubility≤7.5 μg/mm3). The relative growth rate of PU-MA-20 was more than 90% and the L929 cell morphology performs well. Conclusion: For methacrylate based resin, PU-MA is conducive to improve the mechanical strength of traditional dental resin and decrease its water sorption and solubility, which indicates that it may have a good application potential in improving the aging resistance of composite resin.

Key words: resin matrix, poly-urethane, water sorption and solution, mechanical property