以口腔黏膜溃疡为首发表现的结外鼻型NK/T细胞淋巴瘤的多学科诊疗1例

doi:10.13701/j.cnki.kqyxyj.2024.03.017

口腔医学研究 ›› 2024, Vol. 40 ›› Issue (3): 275-278.DOI: 10.13701/j.cnki.kqyxyj.2024.03.017

• 研究生病例精粹———口腔黏膜病系列(3) • 上一篇

以口腔黏膜溃疡为首发表现的结外鼻型NK/T细胞淋巴瘤的多学科诊疗1例

王锋, 陈旭亚, 周刚, 张静^*

口颌系统重建与再生全国重点实验室,口腔生物医学教育部重点实验室,口腔医学湖北省重点实验室,武汉大学口腔医(学)院口腔黏膜科湖北武汉 430079

收稿日期:2024-02-24 出版日期:2024-03-28 发布日期:2024-03-25
通讯作者: * 张静,E-mail:zhangjing.ss@whu.edu.cn
作者简介:王锋(1998~ ),男,江西吉安人,硕士,医师,研究方向:口腔黏膜病学。
基金资助:
国家自然科学基金(编号:82170965)

Multidisciplinary Diagnosis and Treatment of Extranodal Nasal Type NK/T Cell Lymphoma with Oral Mucosal Ulcer as the First Manifestation: A Case Report

WANG Feng, CHEN Xuya, ZHOU Gang, ZHANG Jing^*

State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, Department of Oral Medicine, School and Hospital of Stomatology, Wuhan University, Wuhan 430079, China

Received:2024-02-24 Online:2024-03-28 Published:2024-03-25

摘要/Abstract

摘要： 结外鼻型NK/ T 细胞淋巴瘤(extranodal nasal type NK/T-cell lymphoma,ENKTL)是一种以破坏面部中份结构为主的NK/T细胞来源的非霍奇金淋巴瘤,临床少见。以口腔黏膜溃疡为首发症状的病例罕见且易与其他疾病相混淆,在诊断上极其困难。本文报道1例以颊黏膜及牙龈溃疡为首发表现的ENKTL的多学科诊疗,并分析该疾病的临床病理学特征、诊断、鉴别诊断和治疗,以期为临床诊治相关病例提供参考。

关键词: 结外鼻型NK/T细胞淋巴瘤, 口腔黏膜溃疡, 多学科诊疗

Abstract: Extranodal NK/T cell lymphoma, nasal type (ENKTL), is a rare and unique non-Hodgkin's lymphoma that primarily affects the middle face and originates from T cells or NK cells. It is uncommon for cases to present with an oral ulcer as the initial symptom, which can lead to confusion with other diseases and pose challenges for diagnosis. This paper presents a case study on the diagnosis and treatment of Extranodal NK/T-cell lymphoma, nasal type (ENKTL) with initial symptoms of buccal mucosa and gingival ulcer. It analyzes the clinicopathological characteristics, diagnosis, differential diagnosis, and treatment of the disease to offer guidance for clinical management of similar cases.

Key words: extranodal NK/T cell lymphoma, oral ulcer, multidisciplinary diagnosis and treatment

王锋, 陈旭亚, 周刚, 张静. 以口腔黏膜溃疡为首发表现的结外鼻型NK/T细胞淋巴瘤的多学科诊疗1例[J]. 口腔医学研究, 2024, 40(3): 275-278.

WANG Feng, CHEN Xuya, ZHOU Gang, ZHANG Jing. Multidisciplinary Diagnosis and Treatment of Extranodal Nasal Type NK/T Cell Lymphoma with Oral Mucosal Ulcer as the First Manifestation: A Case Report[J]. Journal of Oral Science Research, 2024, 40(3): 275-278.

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以口腔黏膜溃疡为首发表现的结外鼻型NK/T细胞淋巴瘤的多学科诊疗1例

Multidisciplinary Diagnosis and Treatment of Extranodal Nasal Type NK/T Cell Lymphoma with Oral Mucosal Ulcer as the First Manifestation: A Case Report

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