氢氧化钙封药结合屏障术治疗恒牙根尖孔开放的疗效研究

doi:10.13701/j.cnki.kqyxyj.2025.12.008

口腔医学研究 ›› 2025, Vol. 41 ›› Issue (12): 1059-1064.DOI: 10.13701/j.cnki.kqyxyj.2025.12.008

氢氧化钙封药结合屏障术治疗恒牙根尖孔开放的疗效研究

许可, 徐小茵, 汤雨牧, 沈苏倩, 陆乐^*

苏州口腔医院牙体牙髓科江苏苏州 215000

收稿日期:2025-04-07 出版日期:2025-12-28 发布日期:2025-12-23
通讯作者: *陆乐,E-mail:306988644@qq.com
作者简介:许可(1990~ ),女,江苏苏州人,硕士,主治医师,研究方向:牙体牙髓病学。
基金资助:
苏州市科技局项目(编号:SKYD2023030)苏州市科协(姑苏医星)青年科技人才托举工程项目(编号:GSYX202459)苏州口腔医院院级课题(编号:SZKQYY24B01)

Efficacy of Calcium Hydroxide Medication Combined with Apical Barrier Technique in Treatment of Open Apices in Permanent Teeth

XU Ke, XU Xiaoyin, TANG Yumu, SHEN Suqian, LU Le^*

Department of Conservative Dentistry and Endodontics, Suzhou Stomatological Hospital, Suzhou 215000, China

Received:2025-04-07 Online:2025-12-28 Published:2025-12-23

摘要/Abstract

摘要： 目的: 明确氢氧化钙封药联合iRoot BP Plus根尖屏障术治疗恒牙根尖孔开放慢性根尖周炎的临床疗效及相关影响因素。方法: 回顾性分析2021年1月至2023年12月苏州口腔医院治疗的74颗患牙。患牙均采用Vitapex封药1~35个月,病变控制或形成钙化屏障后行iRoot BP Plus根尖屏障术,术后随访12~47个月。记录性别、年龄、牙位、诊断类型、封药时间、病变面积、根尖孔直径及根尖周指数变化,分析其与疗效的关系。结果: 总有效率为97.3%,治愈率82.4%。年龄、术前病变面积、随访时间、牙位、诊断类型与疗效相关(P<0.05);性别、封药时间及根尖孔直径与疗效无显著关联(P>0.05)。结论: 本治疗方案疗效可靠,尤其适用于年轻、病变范围较小的非囊肿类前磨牙病例,延长随访有助于提升疗效。

关键词: 氢氧化钙, 根尖屏障术, 慢性根尖周炎, 根尖孔开放, 生物陶瓷材料

Abstract: Objective: To evaluate the clinical efficacy and influencing factors of long-term calcium hydroxide medication combined with iRoot BP Plus apical barrier technique in treating chronic apical periodontitis in permanent teeth with open apices. Methods: A retrospective study was conducted on 74 teeth treated at Suzhou Stomatological Hospital from January 2021 to December 2023. All cases received Vitapex for 1-35 months, followed by apical barrier treatment using iRoot BP Plus upon lesion control or calcified barrier formation. Follow-up ranged from 12 to 47 months. Clinical parameters including age, sex, tooth position, diagnosis type, medication duration, lesion area, apical foramen diameter, and PAI score were analyzed in relation to treatment outcomes. Results: The total effective rate was 97.3%, with a healing rate of 82.4%. Age, preoperative lesion area, follow-up duration, tooth position, and diagnosis type were significantly associated with outcomes (P<0.05), while sex, medication duration, and apical foramen diameter were not (P>0.05). Conclusion: This treatment approach is clinically effective and particularly suitable for younger patients with non-cystic premolars and smaller lesions. Extended follow-up may improve outcomes.

Key words: calcium hydroxide, apical barrier technique, chronic apical periodontitis, open apex, bioceramic material

许可, 徐小茵, 汤雨牧, 沈苏倩, 陆乐. 氢氧化钙封药结合屏障术治疗恒牙根尖孔开放的疗效研究[J]. 口腔医学研究, 2025, 41(12): 1059-1064.

XU Ke, XU Xiaoyin, TANG Yumu, SHEN Suqian, LU Le. Efficacy of Calcium Hydroxide Medication Combined with Apical Barrier Technique in Treatment of Open Apices in Permanent Teeth[J]. Journal of Oral Science Research, 2025, 41(12): 1059-1064.

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氢氧化钙封药结合屏障术治疗恒牙根尖孔开放的疗效研究

Efficacy of Calcium Hydroxide Medication Combined with Apical Barrier Technique in Treatment of Open Apices in Permanent Teeth

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