口腔医学研究

口腔医学研究 ›› 2015, Vol. 31 ›› Issue (3): 299-305.

• 临床研究论著 • 上一篇    下一篇

CEREC全瓷嵌体单面与多面修复随访8年的生存状况的Meta分析

李晓莺1,2, 郭家平2, 郭毅3,4*, 刘俊2, 高群2   

  1. 1. 武汉大学公共卫生学院 湖北 武汉 430079;
    2. 广州军区武汉总医院口腔科;
    3. 武汉大学公共卫生学院流行病学教研室;
    4. 武汉大学病毒学国家重点实验室
  • 收稿日期:2014-06-16 出版日期:2015-03-28 发布日期:2016-04-29
  • 通讯作者: 郭毅,E-mail:guoyi@whu.edu.cn
  • 作者简介:李晓莺(1977~ ),女,湖北人,学士,主治医师,主要从事口腔科的临床治疗工作。

A Meta-analysis of the Survival of CEREC Ceramic Inlays and Onlays with 1-surface or Multi-surface Follow up at Least 8 Years.

LI Xiao-ying, GUO Jia-ping, GUO Yi, et al.   

  1. School of Public Health, Wuhan University, Wuhan 430079
  • Received:2014-06-16 Online:2015-03-28 Published:2016-04-29

PDF (PC)

333

被引次数

9

摘要： 目的:探讨CEREC全瓷嵌体在后牙缺损中单面与多面修复随访8年的生存情况。方法:检索Cochrane图书馆,Pubmed,Embase,CBM,中国知网,维普,万方等中英文数据库,截止至2013年12月31日所有文献。纳入后牙牙体缺损患者,实验组为CEREC全瓷嵌体单面修复,对照组为多面修复。研究类型为随机对照试验或同期非随机对照试验。采用Cochrane手册中偏倚风险评价方法进行方法学质量评价,使用GRADE系统评估证据质量等级。结果:3个随访研究纳入分析。共计3538个CEREC全瓷嵌体。结果:CEREC全瓷嵌体生存率二面高于一面(8年)(HR=6.32, 95%CI :1.72~23.20,P=0.005);三面高于一面(8年)(HR=5.87, 95%CI:1.84~18.71,P=0.003),一面与≥四面类似(HR=1.92, 95%CI :0.42~8.79,P=0.4)。GRADE系统评价结果显示2个结局证据水平为低级(一面 vs.二面;一面vs.三面)。1个结局证据水平为极低级(CEREC全瓷嵌体一面vs. ≥四面)。结论:在随访8年的观察中,当前证据表明CEREC全瓷嵌体生存风险并不完全随修复涉及面数增加而增加。

关键词: 嵌体, Cerec, 生存, 长期, HR值

Abstract: Objective: To valuate the survival of CEREC ceramic inlays and onlays with 1-surface and multi-surface after follow up for 8 years. Methods: English databases (Cochrane library, Pubmed, EMbase) and Chinese databases(CBM, VIP, Wan fang ) were searched up to December 31. 2013. Randomized controlled trial and non-randomized trail were collected. The patients with posterior tooth defect were included. We also retrieved special journals, conference proceedings and the references of those studies to avoid omissions. The experiment group was treated with CEREC ceramic inlays or onlays with 1-surface and the control group was CEREC inlays or onlays with multi-surface. Bias risk for individual study was assessed with methods recommended by the Cochrane collaboration and the quality of evidence from this Meta-analysis was assessed with GRADE system. Results: We collected 3 studies totally which included 3538 CEREC ceramic restorations. Results showed that the survival of CEREC ceramic inlays/onlays:2-surface was higher than 1-surface (8 years) (HR=6.32, 95%CI :1.72-23.20, P=0.005); 3-surface was higher than 1-surface (8 years) (HR=5.87, 95%CI :1.84-18.71,P=0.003), and there’s no significant difference between 1-surface and ≥4-surface (HR=1.92, 95%CI :0.42-8.79,P=0.40). Using GRADE system, quality of evidence for 2 outcomes (1-surface vs. 2-surface; 1- surface vs. 3-surface) were low and for 1 outcome (1 surface vs. ≥4surface)was very low. Conclusion: Survival rate(for 8 years) of Cerec ceramic inlays and onlays were reported, the current evidence indicates that the survival rate(for 8 years) do not always increase with the increase of number of surface of inlays or onlays.

Key words: Inlays and onlays , Cerec , Survival , Long-term, HR

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