口腔医学研究

口腔医学研究 ›› 2018, Vol. 34 ›› Issue (2): 144-147.DOI: 10.13701/j.cnki.kqyxyj.2018.02.009

• 口腔肿瘤学研究 • 上一篇    下一篇

修复重建后口腔癌患者生存质量的影响因素分析

秦帅华, 李新明*, 李文鹿*   

  1. 郑州大学第一附属医院口腔颌面外科 河南 郑州 450052;
  • 收稿日期:2017-08-07 出版日期:2018-02-28 发布日期:2018-02-26
  • 通讯作者: 李新明,Email:lxming@zzu.edu.cn
    李文鹿,Email:lwldoctor@163.com
  • 作者简介:秦帅华(1991~ ),男,住院医师,硕士,主要从事口腔颌面外科临床治疗工作。
  • 基金资助:
    国家青年自然科学基金项目(编号:81402578)

Analysis of Influencing Factors of Life Quality of Patients with Oral Cancer after Reconstruction

QIN Shuai-hua,LI Xin-ming*,LI Wen-lu*   

  1. Department Oral and Maxillofacial Surgery,The First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China.
  • Received:2017-08-07 Online:2018-02-28 Published:2018-02-26

PDF (PC)

250

摘要： 目的:生理、社会适应及心理因素严重影响着口腔癌患者的生存质量(Quality of Life,QOL),本研究着重调查口腔癌患者肿瘤切除术后即刻修复重建对其生存质量的影响。方法:通过华盛顿大学生存质量量表中文第四版(UWQOL)评估分别应用胸大肌肌皮瓣(PMM)及游离股前外侧皮瓣(ALT)修复重建的口腔癌术后患者,经过测评得分后对数据进行分析,探讨年龄、性别、颈淋巴结清扫术式、切除的范围、下颌骨断开与否、牙齿情况及放疗情况等因素对患者生存质量影响的程度。结果:此次调查共发放问卷98份,收回问卷85份,回收率86.7%,其中应用胸大肌肌皮瓣修复的患者40例(47%),应用游离股前外侧皮瓣修复的患者45例(53%),在胸大肌肌皮瓣修复的患者组别中,年龄、颈淋巴结清扫术式、下颌骨断开与否及放疗的应用明显影响组内患者的生存质量,而在游离股前外侧皮瓣修复的患者组别中,年龄、性别、颈淋巴结清扫术式、下颌骨断开与否、及放疗的应用则明显影响组内患者的生存质量。结论:这两组患者影响其生存质量的共同因素有年龄、颈淋巴结清扫术式、下颌骨是否断开及放疗应用,因此针对治疗的每一步骤,临床医师应充分考虑患者可能的生存质量的变化。

关键词: 口腔癌, 生存质量, 量表, 皮瓣

Abstract: Objective: To investigate the effect of repair and reconstruction on the quality of life of patients with oral cancer after tumor resection. Methods: The postoperative patients with oral cancer who were reconstituted with the pectoralis major myocutaneous flap (PMM) and the free anterolateral thigh flap (ALT) were assessed respectively with the University of Washington Quality of Life Scale (UWQOL),Chinese version 4.0. After scoring,the data were analyzed to investigate the influence of age, sex, neck dissection, the extent of resection, mandibular central split approach, dental condition, and radiotherapy on the quality of life of patients. Results: The survey issued a total of 98 questionnaires, in which 85 questionnaires were recovered. The recovery rate was 86.7%. Among them, 40 patients (47%) was PMM flap, and 45 patients (53%) was ALT flap. In patients treated with the PMM flap, age, cervical lymph node dissection, mandibular central split approach, and radiotherapy significantly affected the quality of life of the patients. Whereas in patients treated with the ALT flap, age, sex, neck dissection, mandibular central split approach, and radiotherapy significantly affected the quality of life. Conclusion: The common factors affecting the quality of life in both groups were age, neck dissection, mandibular central split approach, and radiotherapy. Clinicians should give full consideration to the possible changes in the quality of life of patients for each step of the treatment.

Key words: Oral cancer, Quality of life, Scale, Flap

中图分类号: