Nd:YAG激光联合康复新液治疗糜烂型OLP疗效纵向观察

口腔医学研究 ›› 2015, Vol. 31 ›› Issue (9): 907-909.

Nd:YAG激光联合康复新液治疗糜烂型OLP疗效纵向观察

胡媛媛,刘宗响^*

徐州市口腔医院牙体牙髓科江苏徐州 221002

收稿日期:2014-12-22 出版日期:2015-09-28 发布日期:2016-05-04
通讯作者: 刘宗响, E-mail:xzkqlzx@163.com
作者简介:胡媛媛(1980~ ),女,江苏人,主治医师,学士,主要从事口腔内科临床方面的研究工作。

Longitudinal Observation on the Efficacy of Pulsed Nd:YAG Laser with Kangfuxin Solution in the Treatment of Erosive Oral Lichen Planus

HU Yuan-yuan, LIU Zong-xiang

Department of Endodontic, Xuzhou Stomatological Hospital, Xuzhou 221002, China

Received:2014-12-22 Online:2015-09-28 Published:2016-05-04

摘要/Abstract

摘要： 目的:评价Nd:YAG激光联合康复新液治疗糜烂型口腔扁平苔藓的纵向疗效。方法:对121例临床经病理确诊的口腔糜烂型扁平苔藓患者随机分为两组,A组41例,使用Nd:YAG激光局部照射联合康复新液湿敷治疗;B组40例,采取康复新液局部湿敷治疗;C组40例,单纯使用Nd:YAG激光局部照射治疗。3组均定期随访24 月,进行统计学分析。结果:3组病例于治疗后2周、1月、6月、24月给予疗效评定。实验A组与B、C两组治疗后2周与1月相比,复发率差异无显著性,显效率差异有统计学意义(P<0.05);治疗后6月及24月实验A组与 B、C两组显效率和复发率比较均有统计学意义(P<0.05)。结论:在合适的照射频率、照射角度、照射时间下,脉冲 Nd:YAG 激光联合康复新液治疗糜烂型扁平苔藓可以迅速达到治疗效果,控制远期复发,提高治愈成功率。

关键词: Nd:YAG激光, 康复新液, 口腔糜烂型扁平苔藓

Abstract: Objective: To evaluate the longitudinal curative effect of pulsed Nd:YAG laser with Kangfuxin solution in the treatment of erosive oral lichen planus (OLP). Methods: An open trial included 121 erosive OLP patients. All patients were randomly divided into three groups: group A (41 patients) was treated with Nd:YAG laser and Kangfuxin solution; group B (40 patients) was treated with Kangfuxin Solution; Group C (40 patients) were treated by local irradiation of Nd:YAG laser. The clinical efficacy was evaluated 24 months after the treatment. Results: There was no significant difference in the recurrent rate between group A, B and C immediate and one month after treatment, however, significant difference in the clinical effective rate (P<0.05). There was a significant difference in both the clinical effective rate and recurrent rate among three groups 6 and 24 months after treatment (P<0.05). Conclusion: Under appropriate irradiation frequency, irradiation angle and exposure time, combination of pulsed Nd:YG laser with Kangfuxin solution has a quick therapeutic effect in the treatment of erosive OLP, with low recurrent rate and high cure rate.

Key words: Nd:YAG lasers, Kangfuxin solution, Erosive oral lichen planus

中图分类号:

R758.65

胡媛媛,刘宗响. Nd:YAG激光联合康复新液治疗糜烂型OLP疗效纵向观察[J]. 口腔医学研究, 2015, 31(9): 907-909.

HU Yuan-yuan, LIU Zong-xiang. Longitudinal Observation on the Efficacy of Pulsed Nd:YAG Laser with Kangfuxin Solution in the Treatment of Erosive Oral Lichen Planus[J]. Journal of Oral Science Research, 2015, 31(9): 907-909.

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