口腔医学研究

口腔医学研究 ›› 2017, Vol. 33 ›› Issue (9): 970-973.DOI: 10.13701/j.cnki.kqyxyj.2017.09.015

• 临床研究论著 • 上一篇    下一篇

Nd:YAG激光、CO2激光局部治疗轻型复发性阿弗他溃疡短期疗效比较研究

李娟1，刘宗响2，段宁1，孙鹏2，王文梅1*   

  1. 1. 南京大学医学院附属口腔医院·南京市口腔医院 江苏 南京 210008；
    2. 徐州市口腔医院 江苏 徐州 221000
  • 收稿日期:2017-03-06 出版日期:2017-09-20 发布日期:2017-09-27
  • 通讯作者: 王文梅,电话:025-83620103
  • 作者简介:李娟(1981~ ),女,江苏人,硕士在读,主治医师,主要从事口腔黏膜方面的临床和基础研究。
  • 基金资助:
    国家自然科学基金项目(编号:81570978、81400521)江苏省临床医学科技专项(编号:BL2014018)

Clinical Short-term Effects of Nd:YAG Laser and CO2 Laser on Minor Aphthous Ulcer

LI Juan1, LIU Zong-xiang2, DUAN Ning1, SUN Peng2, WANG Wen-mei1*   

  1. 1. The Affiliated Stomatological Hospital, School of Medicine, Nanjing University, Nanjing 210008, China;
    2. Xuzhou Stomatological Hospital, Xuzhou 221000, China.
  • Received:2017-03-06 Online:2017-09-20 Published:2017-09-27

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摘要： 目的:比较Nd:YAG激光和CO2激光治疗轻型复发性阿弗他溃疡短期临床疗效。方法:选取68例临床上确诊为轻型复发性阿弗他溃疡的患者,随机分为2组,其中Nd:YAG激光治疗组和CO2激光治疗组各34例。治疗周期3~5 d。应用视觉模拟评分法(VAS)及DP分级法评估并比较两组短期疗效。结果 :在激光照射后的第1天、第2天和第3天分别记录两组疼痛指数减少值,其中Nd:YAG激光减少值为:(3.27±0.24)、(4.23±0.26)和(5.60±0.27);CO2激光组为(2.56±0.27)、(3.40±0.30)和(4.20±0.28),Nd:YAG激光组疼痛指数减少更明显(P<0.05);激光照射治疗后Nd:YAG激光组及CO2激光组的平均溃疡期分别为(4.07±0.82) d和(5.12±0.26) d,差异具有统计学意义(P<0.05),Nd:YAG激光组及CO2激光组总有效率分别为100.0%和90.0%,差异具有统计学意义(P<0.05);同时治疗过程中Nd:YAG激光组患者无明显不适反应,而CO2激光组有6例对疼痛感到紧张,有7例对气味较敏感。结论:Nd:YAG激光治疗MiRAU的疗效优于CO2激光,且舒适度较好。

关键词: 轻型复发性阿弗他溃疡, Nd:YAG激光, CO2激光, 疗效

Abstract: Objective: To compare the clinical short-term effects of Nd:YAG laser and CO2 laser in the treatment of minor aphthous ulcer (MiRAU). Methods: Sixty-eight cases of clinically diagnosed minor aphthous ulcer (MiRAU) patients were randomly divided into 2 groups, namely, the Nd:YAG laser treatment group (Nd:YAG laser group) and CO2 laser treatment group (CO2 laser group) with 34 cases in each group.The treatment period was 3-5 days. By the method of VAS and DP classification, the short-term curative effect of two groups was evaluated and compared. Results: In the first three days after laser treatment, the pain reduction index value of two groups was recorded, respectively. Index value of the Nd: YAG laser was: (3.27±0.24), (4.23±0.26) and (5.60±0.27), which was significantly higher than that of the CO2 laser group with the index value of (2.56±0.27), (3.40±0.30) and (4.20±0.28) (P<0.05). After the laser treatment,Ulcer healing time was(4.07±0.82)days in Nd:YAG laser group, which was significantly shortened than the(5.12±0.26)days in CO2 laser group (P<0.05). The total effective rate was 100.0% in Nd:YAG laser group and 90.0% in CO2 laser group. Nd: YAG laser group of patients showed no obvious reaction. And CO2 laser group has 6 cases of nervous pain, and 7 cases sensitive to smell. Conclusion: Significant effects on the treatment of MiRAU was observed between Nd:YAG laser and CO2 laser group. By comparison, Nd:YAG laser has more advantages in shortening the healing time and relieving pain.

Key words: Recurrent aphthous ulcer , Nd:YAG laser, CO2 laser, Curative effect

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