口腔医学研究

口腔医学研究 ›› 2025, Vol. 41 ›› Issue (6): 531-533.DOI: 10.13701/j.cnki.kqyxyj.2025.06.014

• 病例报告 • 上一篇    下一篇

蓝色橡皮疱痣综合征相关颌面部血管畸形1例

孟鑫1,2, 张静睿1,2, 张诗涵3, 程龙龙4, 侯明2, 王买全2, 蔺栋鹏2, 王永功2*   

  1. 1.河南大学口腔医学院 河南 开封 475001;
    2.河南省人民医院口腔颌面外科 河南 郑州 450003;
    3.郑州大学附属儿童医院 河南 郑州 450003;
    4.郑州大学附属南阳市中心医院 河南 南阳 422000
  • 收稿日期:2024-08-23 发布日期:2025-06-25
  • 通讯作者: *王永功,E-mail:wygkyz@163.com
  • 作者简介:孟鑫(1995~ ),男,郑州人,硕士在读,住院医师,研究方向:口腔颌面外科。
  • 基金资助:
    国家重点研发计划(编号:2018YFC0114505)

Maxillofacial Vascular Malformations Associated with Blue Rubber Bleb Nevus Syndrome: A Case Report

MENG Xin1,2, ZHANG Jingrui1,2, ZHANG Shihan3, CHENG Longlong4, HOU Ming2, WANG Maiquan2, LIN Dongpeng2, WANG Yonggong2*   

  1. 1. Henan University School of Stomatology, Kaifeng 475001, China;
    2. Department of Oral and Maxillofacial Surgery, Henan Provincial People's Hospital, Zhengzhou 450003, China;
    3. Children's Hospital Affiliated to Zhengzhou University, Zhengzhou 450003, China;
    4. Nanyang Central Hospital Affiliated to Zhengzhou University, Nanyang, 422000 China
  • Received:2024-08-23 Published:2025-06-25

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摘要： 蓝色橡皮疱痣综合征(blue rubber bleb nevus syndrome,BRBNS)是一种罕见的全身性血管畸形相关疾病,主要影响皮肤、胃肠道和中枢神经系统。由于其潜在的消化道大出血及脑出血风险,口腔科医师及时识别并转诊至相关科室对改善患者预后及提升其生活质量非常重要。本文报告1例颌面部血管畸形相关的BRBNS患者,并结合文献讨论其临床特点、诊断及治疗策略,旨在提高口腔医师对此疾病的认识,避免漏诊或误诊。

关键词: 颌面部血管畸形, 蓝色橡皮疱痣综合征, 消化道血管畸形, 临床诊疗, 病例报告

Abstract: Blue rubber bleb nevus syndrome (BRBNS) is a rare systemic vascular malformation-related disorder that primarily affects the skin, gastrointestinal tract, and central nervous system. Due to the potential risk of gastrointestinal and cerebral hemorrhage, it is crucial for oral physicians to recognize and refer patients to the appropriate departments to improve prognosis and enhance their quality of life. This article reports a case of BRBNS associated with vascular malformations in the maxillofacial region, and discusses its clinical features, diagnosis, and treatment strategies in conjunction with relevant literature. The aim is to raise awareness among oral physicians about this condition and to prevent missed or misdiagnoses.

Key words: maxillofacial vascular malformations, blue rubber bleb nevus syndrome, gastrointestinal vascular malformations, clinical diagnosis and treatment, case report