原位点种植体再植的存留率及相关影响因素的回顾性分析

doi:10.13701/j.cnki.kqyxyj.2023.08.011

摘要/Abstract

摘要： 目的: 评估分析失败再植的临床预后及相关影响因素。方法: 按照纳入和排除标准严格筛选2016年1月~2021年6月于南京大学医学院附属口腔医院种植科因牙列缺损行种植体再植的患者,记录患者性别、年龄、有无系统病史、是否吸烟、种植位点、种植系统、种植体长度和直径、骨增量与否、再植时机、首次和再次种植时间、失败时间及原因。采用χ²检验及Cox回归分析再植种植体的存留率以及可能存在的影响因素。结果: 最终纳入224例患者,共234颗种植体,其中11颗种植体失败,再植存留率为95.3%。早期失败植体多于晚期失败。通过χ²检验及cox回归分析发现年龄和糖尿病史可显著影响再植种植体存留,吸烟患者的再植种植体失败风险更高。结论: 种植体原位再植仍可获得较高的临床存留率,且患者的年龄、糖尿病史、吸烟史是显著的影响因素,临床需给予高度重视。

关键词: 种植体, 失败再植, 存留率, 影响因素

Abstract: Objective: To evaluate the clinical prognosis and related factors of failed implant replantation. Methods: According to the inclusion and exclusion criteria, patients who underwent implant replantation due to dental defect in a Grade-A dental hospital in Jiangsu from 2016.1 to 2021.6 were strictly screened. The patient's gender, age, systematic medical history, smoking status, implant site, implant system, implant length and diameter, bone increment or not, replantation time, first and second implantation time, and failure time and reason were recorded. Chi-square test and Cox regression were used to analyze the retention rate of replanted implants and the possible influencing factors. Results: A total of 224 patients and 234 implants were included in the study. Eleven implants failed secondly and the replantation retention rate was 95.3%. There were more early failures than late failures. Chi-square test and cox regression analysis showed that age and history of diabetes significantly affected the retention of replantation implants, and smoking patients had a higher risk of implant failure. Conclusion: Implant replantation can still obtain a high clinical survival rate. The patient's age, diabetes history, and smoking history are significant influencing factors.

Key words: dental implants, replantation, survival rate, influencing factors

陈星霖, 陈思, 马文杰, 童昕. 原位点种植体再植的存留率及相关影响因素的回顾性分析[J]. 口腔医学研究, 2023, 39(8): 721-726.

CHEN Xinglin, CHEN Si, MA Wenjie, TONG Xin.. Retrospective Analysis of Survival Rate and Related Factors of Implant Replantation at Previous Failed Site[J]. Journal of Oral Science Research, 2023, 39(8): 721-726.

参考文献

[1] Howe MS, Keys W, Richards D. Long-term (10-year) dental implant survival: A systematic review and sensitivity meta-analysis [J]. J Dent, 2019, 84: 9-21.
[2] Grossmann Y, Levin L. Success and survival of single dental implants placed in sites of previously failed implants [J]. J Periodontol, 2007, 78(9):1670-1674.
[3] Kim YK, Park JY, Kim SG, et al. Prognosis of the implants replaced after removal of failed dental implants [J]. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 2010, 110(3):281-286.
[4] Wang F, Zhang Z, Monje A, et al. Intermediate long-term clinical performance of dental implants placed in sites with a previous early implant failure: A retrospective analysis [J]. Clin Oral Implants Res, 2015, 26(12):1443-1449.
[5] Gomes GH, Misawa MYO, Fernandes C, et al. A systematic review and meta-analysis of the survival rate of implants placed in previously failed sites [J]. Braz Oral Res, 2018, 32: e27.
[6] Sakka S, Baroudi K, Nassani MZ. Factors associated with early and late failure of dental implants [J]. J Investig Clin Dent, 2012, 3(4):258-261.
[7] Staedt H, Rossa M, Lehmann KM, et al. Potential risk factors for early and late dental implant failure: a retrospective clinical study on 9080 implants [J]. Int J Implant Dent, 2020, 6(1):81.
[8] Lin G, Ye S, Liu F, et al. A retrospective study of 30,959 implants: Risk factors associated with early and late implant loss [J]. J Clin Periodontol, 2018, 45(6):733-743.
[9] Mardinger O, Oubaid S, Manor Y, et al. Factors affecting the decision to replace failed implants: A retrospective study [J]. J Periodontol, 2008, 79(12): 2262-2266.
[10] Sendyk DI, Rovai ES, Pannuti CM, et al. Dental implant loss in older versus younger patients: a systematic review and meta-analysis of prospective studies [J]. J Oral Rehabil, 2017, 44(3):229-236.
[11] Park YS, Lee BA, Choi SH, et al. Evaluation of failed implants and reimplantation at sites of previous dental implant failure: survival rates and risk factors [J]. J Periodontal Implant Sci, 2022, 52(3):230-241.
[12] Preshaw PM, Henne K, Taylor JJ, et al. Age-related changes in immune function (immune senescence) in caries and periodontal diseases: a systematic review [J]. J Clin Periodontol, 2017, 44 Suppl 18: S153-S177.
[13] French D, Ofec R, Levin L. Long term clinical performance of 10 871 dental implants with up to 22 years of follow-up: a cohort study in 4247 patients [J]. Clin Implant Dent Relat Res, 2021, 23(3): 289-297.
[14] Mayta-Tovalino F, Mendoza-Martiarena Y, Romero-Tapia P, et al. An 11-year retrospective research study of the predictive factors of peri-implantitis and implant failure: Analytic-multicentric study of 1279 implants in peru [J]. Int J Dent, 2019, 2019: 3527872.
[15] Wagner J, Spille JH, Wiltfang J, et al. Systematic review on diabetes mellitus and dental implants: an update [J]. Int J Implant Dent, 2022, 8(1):1.
[16] Chrcanovic BR, Albrektsson T, Wennerberg A. Diabetes and oral implant failure: a systematic review [J]. J Dent Res, 2014, 93(9):859-867.
[17] Albrektsson T, Chrcanovic B, Östman PO, et al. Initial and long-term crestal bone responses to modern dental implants [J]. Periodontol 2000, 2017, 73(1):41-50.
[18] Nibali L, Gkranias N, Mainas G, et al. Periodontitis and implant complications in diabetes [J]. Periodontol 2000, 2022, 90(1):88-105.
[19] Manzano G, Montero J, Martín-Vallejo J, et al. Risk factors in early implant failure: A meta-analysis [J]. Implant Dent, 2016, 25(2):272-280.
[20] Mustapha AD, Salame Z, Chrcanovic BR. Smoking and dental implants: A systematic review and meta-analysis [J]. Medicina (Kaunas), 2021, 58(1):39.
[21] Barbosa AP, Lourenço JD, Junqueira JJM, et al. The deleterious effects of smoking in bone mineralization and fibrillar matrix composition [J]. Life Sci, 2020, 241: 117132.
[22] Al-Bashaireh AM, Haddad LG, Weaver M, et al. The effect of tobacco smoking on bone mass: An overview of pathophysiologic mechanisms [J]. J Osteoporos, 2018, 2018: 1206235.
[23] Dreyer H, Grischke J, Tiede C, et al. Epidemiology and risk factors of peri-implantitis: A systematic review [J]. J Periodontal Res, 2018, 53(5):657-681.
[24] Ravidà A, Majzoub J, Alassadi M, et al. Impact of implant length on survival of rough-surface implants in nonaugmented posterior areas: a systematic review and meta-regression analysis [J]. Int J Oral Maxillofac Implants, 2019, 34(6):1359-1369.
[25] 何晶,商亚微,邓春富,等. 种植体失败位点再种植的临床回顾分析[J].上海口腔医学,2014,23(2):196-200.
[26] Zhou W, Wang F, Monje A, et al. Feasibility of dental implant replacement in failed sites: A systematic review [J]. Int J Oral Maxillofac Implants, 2016, 31(3):535-545.
[27] Quaranta A, Cicconetti A, Battaglia L, et al. Crestal bone remodeling around platform switched, immediately loaded implants placed in sites of previous failures [J]. Eur J Inflamm, 2012, 1:115-122.