高级氧化技术在种植体周围炎去污领域的应用

doi:10.13701/j.cnki.kqyxyj.2023.05.005

摘要/Abstract

摘要： 种植体周围炎常表现为种植体周围黏膜炎症反应和进行性骨组织丧失,严重时可引起种植体脱落导致治疗失败。清除种植体表面的菌斑生物膜是种植体周围炎治疗的首要原则,尽管目前已有多种表面去污处理方法应用于临床,但仍存在去污效果不够理想,去污过程中会损害植体表面形貌,影响后续钛植体生物相容性等问题。近年来,随着高级氧化技术的蓬勃发展,许多有别于传统治疗方案的种植体表面新型去污方法被提出,其中的一些方法也已应用于临床实践。本文就近年来种植体周围炎植体表面新型去污方法作一综述,以期对未来新方法的选择及临床应用提供参考。

关键词: 种植体周围炎, 种植体表面去污, 高级氧化技术

Abstract: Peri-implantitis is often characterized as inflammation of peri-implant mucosa and progressive loss of marginal bone, which will lead to implant treatment failure. The primary principle for the treatment of peri-implantitis is to achieve a complete removal of plaque biofilm on the implant surface. Although many surface decontamination methods have been applied to clinical treatment, there are still some problems such as unsatisfactory decontamination effect, damage to the implant surface morphology during the decontamination process, and impact on the subsequent biocompatibility. In recent years, with the rapid development of advanced oxidation process technology, many new decontamination methods, which are different from traditional treatment schemes, have been proposed for implant surface decontamination treatment, and some have also been applied in practice. This article reviews the new decontamination methods related to peri-implantitis in recent years, with a view to provide reference for the selection and clinical application of new methods in the future.

Key words: peri-implantitis, decontamination, advanced oxidation process

刘素汝, 田卫东. 高级氧化技术在种植体周围炎去污领域的应用[J]. 口腔医学研究, 2023, 39(5): 402-405.

LIU Suru, TIAN Weidong. Application of Advanced Oxidation Process in Peri-implantitis Surface Decontamination Treatment[J]. Journal of Oral Science Research, 2023, 39(5): 402-405.

参考文献

[1] Diaz P, Gonzalo E, Villagra LJG, et al. What is the prevalence of peri-implantitis? A systematic review and meta-analysis [J]. BMC Oral Health, 2022, 22(1):449.
[2] 陈卓.简述医疗废水处理中高级氧化技术应用[J].清洗世界,2022,38(10):81-83.
[3] 曾春玉,王者馥,蔡芸舟,等.种植体表面去污处理在种植体周围炎治疗中的作用[J].中南大学学报(医学版),2022,47(4):521-528.
[4] Almohandes A, Abrahamsson I, Dionigi C, et al. Surgical treatment of experimental peri-implantitis using mechanical and chemical decontamination procedures: A pre-clinical in vivo study [J]. J Clin Periodontol, 2022, 49(5):518-525.
[5] Han Q, Jiang YL, Brandt BW, et al. Regrowth of microcosm biofilms on titanium surfaces after various antimicrobial treatments [J]. Front Microbiol, 2019, 10:2693.
[6] Lollobrigida M, Fortunato L, Serafini G, et al. The prevention of implant surface alterations in the treatment of peri-implantitis: Comparison of three different mechanical and physical treatments [J]. Int J Environ Res Public Health, 2020, 17(8):2624.
[7] 孙小钦,王旭,韩琪,等.低温等离子体在口腔微生物感染性疾病中的应用研究进展[J].实用医院临床杂志,2022,19(4):199-202.
[8] Lee JY, Kim KH, Park SY, et al. The bactericidal effect of an atmospheric-pressure plasma jet on Porphyromonas gingivalis biofilms on sandblasted and acid-etched titanium discs [J]. J Periodontal Implant Sci, 2019, 49(5):319-329.
[9] Khosravi S, Jafari S, Zamani H, et al. Inactivation of staphylococcus aureus and escherichia coli biofilms by air-based atmospheric-pressure DBD plasma [J]. Appl Biochem Biotechnol, 2021, 193(11):3641-3650.
[10] Kamionka J, Matthes R, Holtfreter B, et al. Efficiency of cold atmospheric plasma, cleaning powders and their combination for biofilm removal on two different titanium implant surfaces [J]. Clin Oral Investig, 2022, 26(3):3179-3187.
[11] Hui WL, Ipe D, Perrotti V, et al. Novel technique using cold atmospheric plasma coupled with air-polishing for the treatment of titanium discs grown with biofilm: An in-vitro study [J]. Dent Mater, 2021, 37(2):359-369.
[12] Modic M, Kovac J, Nicholls JR, et al. Targeted plasma functionalization of titanium inhibits polymicrobial biofilm recolonization and stimulates cell function [J]. Appl Surf Sci, 2019, 487:1176-1188.
[13] Yang Y, Zheng M, Li J, et al. Inhibition of bacterial growth on zirconia abutment with a helium cold atmospheric plasma jet treatment [J]. Clin Oral Investig, 2020, 24(4):1465-1477.
[14] Zhou X, Wu D, Liang D, et al. Evaluation of modified cold-atmospheric pressure plasma (MCAP) for the treatment of peri-implantitis in beagles [J]. Oral Dis, 2022, 28(2):495-502.
[15] Evert K, Kocher T, Schindler A, et al. Repeated exposure of the oral mucosa over 12 months with cold plasma is not carcinogenic in mice [J]. Sci Rep, 2021, 11(1):20672.
[16] Zhang C, Yu Z, Wang X. A review of electrochemical oxidation technology for advanced treatment of medical wastewater [J]. Front Chem, 2022, 10:1002038.
[17] Zipprich H, Weigl P, Di Gianfilippo R, et al. Comparison of decontamination efficacy of two electrolyte cleaning methods to diode laser, plasma, and air-abrasive devices [J]. Clin Oral Investig, 2022, 26(6):4549-4558.
[18] Kyaw TT, Hanawa T, Kasugai S. Investigation of different electrochemical cleaning methods on contaminated healing abutments in vitro: an approach for metal surface decontamination [J]. Int J Implant Dent, 2020, 6(1):64.
[19] Ossowska A, Olive JM, Zielinski A, et al. Effect of double thermal and electrochemical oxidation on titanium alloys for medical applications[J].Appl Surf Sci, 2021, 563:150340.1-150340.13.
[20] Goltz M, Koch M, Detsch R, et al. Influence of in-situ electrochemical oxidation on implant surface and colonizing microorganisms evaluated by scanning electron microscopy [J]. Materials (Basel), 2019, 12(23):3977.
[21] Koch M, Goltz M, Xiangjun M, et al. Electrochemical disinfection of dental implants experimentally contaminated with microorganisms as a model for Periimplantitis [J]. J Clin Med, 2020, 9(2):475.
[22] Kaiser F, Scharnweber D, Bierbaum S, et al. Success and side effects of different treatment options in the low current attack of bacterial biofilms on titanium implants [J]. Bioelectrochemistry, 2020, 133:107485.
[23] Schlee M, Rathe F, Brodbeck U, et al. Treatment of peri-implantitis-electrolytic cleaning versus mechanical and electrolytic cleaning-A randomized controlled clinical trial-six-month results [J]. J Clin Med, 2019, 8(11):1909.
[24] Schlee M, Wang HL, Stumpf T, et al. Treatment of periimplantitis with electrolytic cleaning versus mechanical and electrolytic cleaning: 18-month results from a randomized controlled clinical trial [J]. J Clin Med, 2021, 10(16):3475.
[25] Bosshardt DD, Brodbeck UR, Rathe F, et al. Evidence of re-osseointegration after electrolytic cleaning and regenerative therapy of peri-implantitis in humans: a case report with four implants [J]. Clin Oral Investig, 2022, 26(4):3735-3746.
[26] Meenakshi PS, Rajasekar A. A review on ozone therapy in periodontitis [J]. Bioinformation, 2022, 18(7):634-639.
[27] Yang YY, Zhang HH, Komasa S, et al. UV/ozone irradiation manipulates immune response for antibacterial activity and bone regeneration on titanium [J]. Mater Sci Eng C Mater Biol Appl, 2021, 129:112377.
[28] Murakami M, Nagano K, Hamaoka K, et al. Ozone water bactericidal and cleaning effects on oral diseases-related planktonic and bacterial biofilms [J]. J Hard Tissue Biol, 2021, 30(1):27-31.
[29] Faccioni F, Bevilacqua L, Porrelli D, et al. Ultrasonic instrument effects on different implant surfaces: profilometry, energy-dispersive X-ray spectroscopy, and microbiology in vitro study [J]. Int J Oral Maxillofac Implants, 2021, 36(3):520-528.
[30] Takechi M, Takamoto M, Ninomiya Y, et al. In vitro investigation of the cell compatibility and antibacterial properties of titanium treated with calcium and ozone [J]. Dent Mater J, 2021, 40(3):712-718.
[31] Isler SC, Soysal F, Akca G, et al. The effects of decontamination methods of dental implant surface on cytokine expression analysis in the reconstructive surgical treatment of peri-implantitis [J]. Odontology, 2021, 109(1):103-113.
[32] Bono N, Ponti F, Punta C, et al. Effect of UV irradiation and TiO₂-photocatalysis on airborne bacteria and viruses: An overview [J]. Materials, 2021, 14(5):1075.
[33] Sousa V, Mardas N, Spratt D, et al. The effect of microcosm biofilm decontamination on surface topography, chemistry, and biocompatibility dynamics of implant titanium surfaces [J]. Int J Mol Sci, 2022, 23(17):10033.
[34] Wu H, Xie L, He M, et al. A wear-resistant TiO₂ nanoceramic coating on titanium implants for visible-light photocatalytic removal of organic residues [J]. Acta Biomater, 2019, 97:597-607.
[35] Nakamura K, Shirato M, Tenkumo T, et al. Hydroxyl radicals generated by hydrogen peroxide photolysis recondition biofilm-contaminated titanium surfaces for subsequent osteoblastic cell proliferation [J]. Sci Rep, 2019, 9(1):4688.
[36] Caccianiga G, Rey G, Caccianiga P, et al. Laser management of peri-implantitis: A comparison between photodynamic therapy combined with hydrogen peroxide (OHLLT) and OHLLT + Er:YAG laser. A retrospective controlled study [J]. Appl Sci, 2021, 11(15):6771.
[37] Lee EH, Lee SW, Seo Y, et al. Manganese oxide nanozyme-doped diatom for safe and efficient treatment of peri-implantitis [J]. ACS Appl Mater Interfaces, 2022, 14(24):27634-27650.