聚氨酯低聚物对光固化树脂基质性能的影响

doi:10.13701/j.cnki.kqyxyj.2023.11.012

口腔医学研究 ›› 2023, Vol. 39 ›› Issue (11): 1000-1004.DOI: 10.13701/j.cnki.kqyxyj.2023.11.012

聚氨酯低聚物对光固化树脂基质性能的影响

冯丹^*, 杨政远, 温雅晴, 林岐

吉林大学口腔医院修复科吉林长春 130021

收稿日期:2023-06-20 出版日期:2023-11-28 发布日期:2023-11-22
通讯作者: ^*冯丹,E-mail:fengdudu1989@163.com
作者简介:冯丹(1989~ )女,吉林四平人,博士,主治医师,研究方向:牙科修复材料。
基金资助:
国家自然科学基金(编号:82071163)吉林省科技厅国际科技合作项目(编号:20220402077GH)

Effect of Poly-urethane Oligomer on Properties of Light-cured Dental Resin

FENG Dan^*, YANG Zhengyuan, WEN Yaqing, LIN Qi

Department of Prosthodontics, School and Hospital of Stomatology, Jilin University, Changchun 130021, China

Received:2023-06-20 Online:2023-11-28 Published:2023-11-22

摘要/Abstract

摘要： 目的: 合成一种聚氨酯-二甲基丙烯酸酯低聚物(PU-MA),应用于牙科可见光固化树脂基质以改善其综合性能。方法: 以BPA、IPDI和HEMA为原料合成PU-MA,并与POSS-MA、Bis-GMA/TEGDMA共混配制新型可见光固化树脂基质,通过物理-机械性能和体外细胞毒性检测,评价其综合性能;采用SPSS20.0统计软件对数据进行单因素和双因素方差分析。结果: 20wt% PU-MA使树脂基质的挠曲强度达(124.51±6.00) MPa,高于ISO 4049要求的下限(≥90 MPa);吸水和溶解值为(25.93±1.47) μg/mm³和(0.50±0.08) μg/mm³,低于ISO 4049要求的上限(吸水值≤40 μg/mm³,溶解值≤7.5 μg/mm³);体外细胞毒性试验表明,L929细胞增殖率大于90%,且细胞生长形态良好。结论: 在一定条件下(对于甲基丙烯酸酯基树脂),PU-MA可有效提高传统树脂基质的力学性能,降低其吸水和溶解性,在改善复合树脂耐老化性能方面可能具有较好的应用潜力。

关键词: 树脂基质, 聚氨酯, 吸水和溶解性, 机械性能

Abstract: Objective: To improve the comprehensive performance of dental resin matrix through a new polyurethane-dimethacrylate oligomer (PU-MA). Methods: BPA, IPDI, and HEMA were used to synthesize the PU-MA, and the new dental resin matrix was prepared by combining the PU-MA with Bis-GMA/TEGDMA resin matrix reinforced by 5 wt% POSS-MA. The mechanical-physical properties and in vitro cytotoxicity were tested. Results: The flexible strength of PU-MA-20 was up to (124.51±6.00) MPa, which was higher than the minimum standard of ISO 4049(≥90 MPa); the water absorption and solubility were (25.93±1.47) μg/mm³ and (0.50±0.08) μg/mm³, which were lower than the maximum standard of ISO 4049(water absorption≤40 μg/mm³, water solubility≤7.5 μg/mm³). The relative growth rate of PU-MA-20 was more than 90% and the L929 cell morphology performs well. Conclusion: For methacrylate based resin, PU-MA is conducive to improve the mechanical strength of traditional dental resin and decrease its water sorption and solubility, which indicates that it may have a good application potential in improving the aging resistance of composite resin.

Key words: resin matrix, poly-urethane, water sorption and solution, mechanical property

冯丹, 杨政远, 温雅晴, 林岐. 聚氨酯低聚物对光固化树脂基质性能的影响[J]. 口腔医学研究, 2023, 39(11): 1000-1004.

FENG Dan, YANG Zhengyuan, WEN Yaqing, LIN Qi. Effect of Poly-urethane Oligomer on Properties of Light-cured Dental Resin[J]. Journal of Oral Science Research, 2023, 39(11): 1000-1004.

参考文献

[1] Borges CM, Krishnamurthy M. Are we getting any better? A critical analysis of selected healthy people 2020 oral health indicators in 1999-2004 and 2013-2016, USA[J]. Int J Environ Res Public Health, 2022, 19(9): 5250.
[2] Brunthaler A, König F, Lucas T, et al. Longevity of direct resin composite restorations in posterior teeth: a review[J]. Clin Oral Investig, 2003, 7(2): 63-70.
[3] Heintze SD, Rousson V. Clinical effectiveness of direct class Ⅱ restorations-a meta-analysis[J]. J Adhes Dent, 2012, 14(5): 407-431.
[4] Heintze SD, Ilie N, Hickel R, et al. Laboratory mechanical parameters of composite resins and their relation to fractures and wear in clinical trials-A systematic review[J]. Dent Mater, 2016, 33(3): e101-e114.
[5] Ligon-Auer SC, Schwentenwein M, Gorsche C, et al. Toughening of photo-curable polymer networks: A review[J]. Polym Chem, 2016, 7(2): 257-286.
[6] Szczesio-Wlodarczyk A, Sokolowski J, Kleczewska J, et al. Ageing of dental composites based on methacrylate resins-A critical review of the causes and method of assessment[J]. Polymers (Basel), 2020, 12(4): 882.
[7] Szczesio-Wlodarczyk A, Fronczek M, Ranoszek-Soliwoda K, et al. The first step in standardizing an artificial aging protocol for dental composites-evaluation of basic protocols[J]. Molecules, 2022, 27(11): 3511.
[8] Lichtenhan JD, Vu NQ, Carter JA, et.al. Silsesquioxane-siloxane copolymers from polyhedral Silsesquioxane[J]. Macromolecules, 1993, 26(8): 2141-2142.
[9] Wu X, Sun Y, Xie W, et. al. Development of novel dental nanocomposites reinforced with polyhedral oligomeric silsesquioxane (POSS)[J]. Dent Mater, 2010, 26(5): 456-462.
[10] Feng D, Guo X, Jiang X, et al. Properties of methacryl polyhedral oligomeric silsesquioxane (POSS-MA) doped methacrylate-based dental resins and composites containing glass flake/Ba-Al-SiO₂ glass powder as inorganic dental fillers[J]. Acta Medica Mediterranea, 2019, 35(1): 87-92.
[11] Chen CY, Huang XK, Lin SP, et al. Low-shrinkage visible-light-curable urethane-modified epoxy acrylate/SiO₂ composites as dental restorative materials[J]. Compos Sci Technol, 2008, 68(13): 2811-2817.
[12] Minch MJ. An introduction to hydrogen bonding[J]. J Chem Educ, 1999, 76(6):759.
[13] Sánchez G. Introduction to "intramolecular Hydrogen Bonding 2018"[J]. Molecules, 2019, 24(16): 2858.
[14] Ferracane JL. Hygroscopic and hydrolytic effects in dental polymer networks[J]. Dent Mater, 2006, 22(3): 211-222.
[15] Gonçalves F, Kawano Y, Pfeifer C, et al. Influence of BisGMA, TEGDMA, and BisEMA contents on viscosity, conversion, and flexural strength of experimental resins and composites[J]. Eur J Oral Sci, 2009, 117(4): 442-446.
[16] Barszczewska-Rybarek IM. Structure-property relationships in dimethacrylate networks based on Bis-GMA, UDMA and TEGDMA[J]. Dent Mater, 2009, 25(9): 1082-1089.
[17] Peutzfeldt A. Resin composites in dentistry: the monomer systems[J]. Eur J Oral Sci, 1997, 105(2): 97-116.
[18] Huang W, Ren L, Cheng Y, et al. Evaluation of the color stability, water sorption, and solubility of current resin composites[J]. Materials (Basel), 2022, 15(19):6710.
[19] Klauer E, Belli R, Petschelt A, et al. Mechanical and hydrolytic degradation of an Ormocer^®-based Bis-GMA-free resin composite[J]. Clin Oral Investig, 2019, 23(5):2113-2121.

聚氨酯低聚物对光固化树脂基质性能的影响

Effect of Poly-urethane Oligomer on Properties of Light-cured Dental Resin

PDF (PC)

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 5

编辑推荐

Metrics

[1]	马鸿翼, 杨东梅. 大块充填树脂在乳牙修复中的应用和研究进展[J]. 口腔医学研究, 2022, 38(12): 1124-1127.
[2]	李一帆, 周志伟, 汪振华. 快速烧结系统对氧化锆机械性能的影响[J]. 口腔医学研究, 2021, 37(4): 339-343.
[3]	李迪, 李保泉, 魏玉雪, 牛菊, 赵文迪, 刘丹丹, 那辉, 刘晓秋. 新型牙科复合树脂的制备与机械性能研究[J]. 口腔医学研究, 2018, 34(11): 1232-1234.
[4]	高士军, 贾小可, 李益玲, 李雯雯, 谭小丽, 肖媛媛, 王东霞, 黄艳军, 姜家真. 添加硼酸铝晶须对硅橡胶软衬机械性能的影响[J]. 口腔医学研究, 2015, 31(6): 594-596.
[5]	初明慧,高士军,魏思怡,任国欣,王冬霞,肖媛媛. 改性纳米氧化铈对义齿树脂基托机械性能的影响[J]. 口腔医学研究, 2015, 31(10): 978-980.