口腔医学研究 ›› 2020, Vol. 36 ›› Issue (1): 7-9.DOI: 10.13701/j.cnki.kqyxyj.2020.01.002

• 综述 • 上一篇    下一篇

感染根管细菌内毒素的致病机制与清除策略

侯亚静, 黄定明*   

  1. 口腔疾病研究国家重点实验室,国家口腔疾病临床研究中心,四川大学华西口腔医院牙体牙髓病科 四川 成都 610041
  • 收稿日期:2019-02-16 出版日期:2020-01-28 发布日期:2020-01-16
  • 通讯作者: 黄定明,E-mail:dingminghuang@163.com
  • 作者简介:侯亚静(1994~ ),女,河北邯郸人,硕士在读,主要研究方向为牙体牙髓病学。
  • 基金资助:
    国家自然科学基金(编号:81771063)四川大学专职博士后研发基金(编号:20826041B4105)

Pathogenic Mechanism and Clearance Strategy of Bacterial Endotoxin in Infected Root Canal

HOU Yajing, HUANG Dingming*   

  1. State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases & Department of Cariology and Endodonics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
  • Received:2019-02-16 Online:2020-01-28 Published:2020-01-16

摘要: 细菌内毒素会影响牙髓根尖周疾病的发生发展及其治疗的预后。探究细菌内毒素的致病机制及清除措施对提高根管治疗的成功率及获得远期良好预后均有重要意义。本文就根管内细菌内毒素的产生、分布、致病机制以及清除策略等方面作一综述,为临床及基础研究提供新依据和新思路。

关键词: 细菌内毒素, 牙髓根尖周疾病, 根管治疗

Abstract: Bacterial endotoxin plays an important role in the development of pulpitis and periapical periodontitis. The exploration of the pathogenesis of endotoxin and the elimination of endotoxin from the root canal system could contribute the success of root canal treatment and the long-term postoperative effect. In this review, the research progress on the pathogenic mechanism and the removing of bacterial endotoxin in pulpitis and periapical periodontitis was mainly introduced.

Key words: endotoxin, pulpitis and periapical periodontitis, root canal therapy