鼠在组织工程骨促骨形成研究中的应用及进展

doi:10.13701/j.cnki.kqyxyj.2020.01.004

摘要/Abstract

摘要： 组织工程骨修复骨缺损作为一种现代化的优良方式,一度成为研究热点。鼠类因其经济、效果稳定、能模拟多种人类疾病模型而成为多数研究骨组织再生实验对象。本文广泛查阅近年来在鼠体内构建骨再生模型的有关文献,对将鼠应用于组织工程骨促骨形成实验中的影响因素进行综述,包括鼠的种类、性别、年龄、免疫功能、组织工程骨的移植方式以及骨缺损部位等,总结特点,以供实验者参考。

关键词: 组织工程骨, 动物模型, 鼠类, 骨生成

Abstract: As a modern and excellent way, tissue engineered bone has been a research focus to repaire bone defects in recent decades. Because of its low cost, stable effect, and stimulation of human diseases, murine has become the widely used animal models for bone osteogenesis tests. In this paper, several factors including the species, sex, age, and immunity of murine, the transplantion methods of tissue engineered bone and the cites of bone defects are summarized based on the review of the relevant literature about bone osteogenesis experiments using tissue engineered bone within murine in recent years to provide references for the future researchers.

Key words: tissue engineered bone, animal model, murine, osteogenesis

吴佳, 刘志辉. 鼠在组织工程骨促骨形成研究中的应用及进展[J]. 口腔医学研究, 2020, 36(1): 13-15.

WU Jia, LIU Zhihui. Application and Progress of Murine in the Study of Osteogenesis Induced by Tissue Engineered Bone.[J]. Journal of Oral Science Research, 2020, 36(1): 13-15.

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