6例下颌骨Garrè's骨髓炎临床分析

doi:10.13701/j.cnki.kqyxyj.2020.07.016

口腔医学研究 ›› 2020, Vol. 36 ›› Issue (7): 678-682.DOI: 10.13701/j.cnki.kqyxyj.2020.07.016

6例下颌骨Garrè's骨髓炎临床分析

叶斯哈提·木合塔尔, 克热木·阿巴司, 胡露露, 龚忠诚^*

新疆医科大学口腔医院,新疆医科大学口腔医学院新疆乌鲁木齐 830054

收稿日期:2019-10-24 出版日期:2020-07-28 发布日期:2020-07-24
通讯作者: 龚忠诚,E-mail:565249755@qq.com
作者简介:叶斯哈提·木合塔尔(1992~),男,新疆人,硕士在读,研究方向:颌骨骨髓炎。

Clinical Characteristic of 6 Patients with Garrè's Osteomyelitis

Yesihati·MUHETAER, Keremu·ABASI, HU Lulu, GONG Zhongcheng^*

School and Hospital of Stomatology, Xinjiang Medical University, Urumqi 830054, China

Received:2019-10-24 Online:2020-07-28 Published:2020-07-24

摘要/Abstract

摘要： 目的: 本文通过分析颌骨Garrè's骨髓炎患者的一般情况,临床特征,感染来源,分布及治疗,为颌骨Garrè's骨髓炎的防治,诊断及治疗提供依据。方法: 收集2015年 2月~2017 年10月期间新疆医科大学第一附属医院口腔颌面肿瘤外科收治的6例Garrè's颌骨骨髓炎的患者病例资料,对患者的一般情况、临床特征、感染来源,分布及治疗进行分析。结果: 6例颌骨Garrè's骨髓炎患者中,男女各3例,平均年龄11.6岁,住院天数8 d,平均病程99 d。 4例患者为非牙源性感染(67% );2例患者为牙源性感染(33%);Garrè's颌骨骨髓炎影像学特点为致密性骨硬化伴骨膜新骨形成。结论: Garrè's颌骨骨髓炎是一种常累及单侧下颌骨的特殊骨质紊乱性慢性骨髓炎,病因与牙源性感染,内分泌及外伤有关。手术治疗辅助抗炎治疗是Garrè's颌骨骨髓炎的最佳治疗方案。

关键词: Garrè's骨髓炎, 颌骨骨髓炎, 下颌骨

Abstract: Objective: To provide a basis for the prevention, diagnosis, and treatment of Garrè's osteomyelitis in the jaw by analyzing the general condition, clinical features, source, distribution, and treatment of patients with Garrè's osteomyelitis. Methods: The clinical data of 6 patients with Garrè's osteomyelitis treated in the Department of Oral and Maxillofacial Surgery of the First Affiliated Hospital of Xinjiang Medical University were analyzed from May 2013 to May 2015, including the patient's general condition, clinical characteristics, source of infection, distribution, and treatment. Results: Of the 6 patients with Garrè's osteomyelitis of the jaw, 3 were male and 3 were female, with an average age of 11.6 years, 8 days of hospitalization, and an average duration of 99 days. 4 patients were non-dental infections (67%). 2 patients had odontogenic infections (33%). The jaws of Garrè's osteomyelitis often involved the mandible. It had facial asymmetry and local swelling. The imaging feature of Garrè's jaw osteomyelitis was dense osteosclerosis with periosteal new bone formation. Conclusion: Garrè's osteomyelitis is a special osteoporotic chronic osteomyelitis,which often involved the unilateral mandible. The etiology is related to odontogenic infection, endocrine, and trauma. Surgical treatment of adjuvant anti-inflammatory treatment is the best treatment for Garrè's osteomyelitis.

Key words: Garre's osteomyelitis, jaw bone, mandibular bone

叶斯哈提·木合塔尔, 克热木·阿巴司, 胡露露, 龚忠诚. 6例下颌骨Garrè's骨髓炎临床分析[J]. 口腔医学研究, 2020, 36(7): 678-682.

Yesihati·MUHETAER, Keremu·ABASI, HU Lulu, GONG Zhongcheng. Clinical Characteristic of 6 Patients with Garrè's Osteomyelitis[J]. Journal of Oral Science Research, 2020, 36(7): 678-682.

参考文献

[1] Suei Y, Taguchi A, Tanimoto K. Diagnosis and classification of mandibular osteomyelitis[J]. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 2005, 100(2):207-214.
[2] 高攀,王晓毅,宣鸣,等.累及双侧下颌骨Garrè's骨髓炎1例[J].华西口腔医学杂志,2015,33(4):436-438.
[3] Wood RE, Nortjé CJ, Grotepass F, et al. Periostitis ossificans versus Garrè's osteomyelitis. Part Ⅰ. What did Garrè really say?[J]. Oral Surg Oral Med Oral Pathol, 1988, 65(6):773-777.
[4] Nakano H, Miki T, Aota K, et al. Garrè's osteomyelitis of the mandible caused by an infected wisdom tooth[J]. Oral Sci Int, 2008, 5(2):150-154.
[5] Suma R, Vinay C, Shashikanth MC, et al. Garre's sclerosing osteomyelitis[J]. J Indian Soc Pedod Prev Dent, 2007, 25 Suppl:S30-S33.
[6] Erişn M, BayarÖF, Ak G. Garre osteomyelitis: a case report[J]. The Journal of Dental Faculty of Atatürk University, 2014, 9:49-53.
[7] Jayasenthil A, Aparna P , Balagopal S. Non-surgical endodontic management of Garre's osteomyelitis: a case report[J]. Br J Med Med Res, 2015, 9(3):1-4.
[8] Brazao-Silva MT, Pinheiro TN. The so-called Garrè's osteomyelitis of jaws and the pivotal utility of computed tomography scan[J]. Contemp Clin Dent, 2017, 8(4): 645-646.
[9] Gonçalves M , Oliveira DP, Oya EO, et al. Garre's osteomyelitis associated with a fifistula: a case report[J]. J Clin Pediatr Dent, 2002, 26(3): 311-313.
[10] Karjodkar FR. Textbook of dental and maxillofacial radiology[M]. 2nd edition, 2009
[11] Singh D, Subramaniam P, Bhayya PD. Periostitis ossificans (Garrè's osteomyelitis): An unusual case[J]. J Indian Soc Pedod Prev Dent, 2015, 33(4):344-346.
[12] Bai S, Zhang H, Li ZA, et al. 53-year-old man with a sclerosing rib lesion: A case report[J]. Medicine (Baltimore), 2017, 96(47):e8692.
[13] Elera-Fitzcarrald C, Alfaro-Lozano JL, Pastor-Asurza CA. Garre's sclerosing osteomyelitis caused by salmonella group D in a patient with systemic lupus erythematosus: an unusual complication[J]. Clin Rheumatol, 2015, 34(12):2155-2158.
[14] Felsberg GJ, Gore RL, Schweitzer ME, et al. Sclerosing osteomyelitis of Garrè (periostitis ossificans)[J]. Oral Surg Oral Med Oral Pathol, 1990, 70(1):117-120.
[15] Nortjé CJ, Wood RE, Grotepass F. Periostitis ossifificans versus Garrè's osteomyelitis-part Ⅱ: radiologic analysis of 93 cases in the jaws[J]. Oral Surg Oral Med Oral Pathol, 1988, 66(2): 249–260.
[16] Park J, Myoung H. Chronic suppurative osteomyelitis with proliferative periostitis related to a fully impacted third molar germ: a report of two cases[J]. J Korean Assoc Oral Maxillofac Surg, 2016, 42(4):215-220.
[17] 吴晓玲,郑茜,吕佳岭,等.雌激素微环境下非经典 Wnt/Ca²⁺信号通路调控人牙周膜干细胞成骨分化的研究[J].口腔医学研究,2019,35(1):33-37.
[18] 程海燕,沈兰花, 张瑞,等.雌孕激素对人牙周膜细胞成骨分化影响的研究[J].口腔医学研究,2019,35(7):657-659.
[19] White SC,Pharoah MJ. Oral Radiology: Principles and Interpretation[M].Mosby, St. Louis, MO, USA, 6th edition, 2009.

6例下颌骨Garrè's骨髓炎临床分析

Clinical Characteristic of 6 Patients with Garrè's Osteomyelitis

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