口腔医学研究

口腔医学研究 ›› 2021, Vol. 37 ›› Issue (4): 349-353.DOI: 10.13701/j.cnki.kqyxyj.2021.04.016

• 口腔修复学研究 • 上一篇    下一篇

黄芩素与葛根素对牙本质粘接持久性的影响

牟亚群1, 高士军1*, 汝晓娜2, 尹通3, 肖媛媛1, 初明慧2, 刘苗1   

  1. 1.佳木斯大学附属口腔医院 黑龙江 佳木斯 150001;
    2.佳木斯大学附属第二医院 黑龙江 佳木斯 150001;
    3.佳木斯大学 黑龙江 佳木斯 150001
  • 收稿日期:2020-12-03 发布日期:2021-04-15
  • 通讯作者: *高士军,E-mail:gaoshijun822@163.com
  • 作者简介:牟亚群(1992~ ),女,山东日照人,硕士在读,主要从事口腔修复方向的研究工作。

Effects of Baicalein and Puerarin on Dentin Bonding Durability

MOU Yaqun1, GAO Shijun1*, RU Xiaona2, YIN Tong3, XIAO Yuanyuan1, CHU Minghui2, LIU Miao1   

  1. 1. The Affiliated Stomatological Hospital of Jiamusi University, Jiamusi 150001, China;
    2. The Second Affiliated Hospital of Jiamusi University, Jiamusi 150001, China;
    3. Jiamusi University, Jiamusi 150001, China
  • Received:2020-12-03 Published:2021-04-15

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摘要： 目的: 探讨基质金属蛋白酶抑制剂黄芩素,葛根素结合乙醇湿粘接对牙本质粘接持久性的影响。方法: 选取128颗离体牙,随机分为8个组,每组16个,A组对照组无处理; B组乙醇处理;C、D、E组分别为0.05%、0.1%、0.5%黄芩素乙醇处理;F、G、H组分别为0.05%、0.1%、0.5%葛根素乙醇处理,每组随机抽取8个试件进行老化处理。各组试件进行剪切强度测试,断裂模式分析,扫描电镜观察粘接面,断裂面微观结构。结果: C~H组即刻剪切强度高于A、B组(P<0.05),老化后C~H组剪切强度比即刻组没有明显降低(P>0.05),老化后A、B组剪切强度明显降低(P<0.05)。扫描电镜观察:老化后实验组的混合层树脂突致密程度高于对照组。结论: 黄芩素,葛根素结合乙醇湿粘接方式可以提高牙本质即刻粘接强度,增强牙本质粘接持久性。

关键词: 牙本质粘接, 黄芩素, 葛根素, 乙醇湿粘接

Abstract: Objective: To investigate the effects of matrix metalloproteinase inhibitor baicalein and puerarin combination with ethanol wet bonding on the durability of dentin bonding. Methods: 128 isolated teeth were selected and randomly divided into 8 groups, 16 in each group. Group A was control group, group B was treated with ethanol, groups C, D and E were treated with 0.05%, 0.1% and 0.5% baicalein ethanol. Group F-H were treated with 0.05%, 0.1% and 0.5% puerarin ethanol, and 8 specimens were randomly selected for aging treatment in each group. Each group of specimens was subjected to shear strength test, fracture mode analysis, and scanning electron microscope observation of the mixed layer. Results: The immediate shear strengths of group C-H were higher than those of group A and B (P<0.05). The shear strengths of group C-H were not significantly reduced after aging (P>0.05), however, the shear strengths of group A and B were significantly reduced after aging (P<0.05). Scanning electron microscope observation found that the resin densification degree of mixed layer in the experimental group was higher than that in the control group. Conclusion: The wet bonding of baicalin and puerarin combined with ethanol can improve the immediate bonding strength of dentin and enhance the duration of dentine bonding.

Key words: dentin bonding, baicalein, puerarin, alcohol wet bonding