口腔医学研究

口腔医学研究 ›› 2022, Vol. 38 ›› Issue (5): 429-435.DOI: 10.13701/j.cnki.kqyxyj.2022.05.009

• 牙周病学研究 • 上一篇    下一篇

234例牙龈瘤患者的临床特征及复发防范分析

柯晓菁, 金讴, 闫福华, 李艳芬, 李厚轩*   

  1. 南京大学医学院附属口腔医院·南京市口腔医院牙周病科 210008
  • 收稿日期:2021-11-25 出版日期:2022-05-28 发布日期:2022-05-20
  • 通讯作者: *李厚轩,E-mail:lihouxuan3435_0@163.com
  • 作者简介:柯晓菁(1989~ ),女,福建人,医师,硕士,主要从事牙周炎的发病机制研究等。
  • 基金资助:
    国家自然科学基金面上项目(编号:81670996) 江苏省卫生健康委科研项目(编号:H2019033) 南京市医学科技发展资金(编号:QRX17025) 南京市口腔疾病临床医学研究中心(编号:2019060009)

Clinical Features and Relapse Prevention of Epulis: A Retrospective Study of 234 Cases

KE Xiaojing, JIN Ou, YAN Fuhua, LI Yanfen, LI Houxuan   

  1. Department of Periodontics, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing 210008, China
  • Received:2021-11-25 Online:2022-05-28 Published:2022-05-20

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摘要： 目的: 分析牙龈瘤的临床特征,为探讨牙龈瘤的生物学行为和复发防范提供参考。方法: 选择2018~2019年于南京大学医学院附属口腔医院牙周科门诊和术后病理诊断均为牙龈瘤的患者,对临床资料进行回顾性分析。结果: 总共纳入234例牙龈瘤患者,好发年龄为21~30岁,男女比例约为1∶2.2,其中31~70岁年龄组中女性多发(P<0.05),30岁以下年龄组的男女比例无统计学差异(P>0.05)。各型分布由多至少依次是纤维性龈瘤121例(51.71%),肉芽肿性龈瘤76例(32.48%),血管性龈瘤36例(15.38%),巨细胞性龈瘤1例(0.43%)。上下颌分布无明显差别(P>0.05),前牙区较后牙区多发(P<0.001)。此外,牙龈瘤好发于唇颊侧(66.67%),最少见于缺牙区(1.28%);瘤体直径0.3~2.2 cm,多数分布于0.6~1.5 cm范围(78.2%);牙周系统治疗后短期复发2例,复发率为0.85%。结论: 牙龈瘤女性多发,好发年龄为21~30岁,多见于前牙区和唇颊侧,其中纤维性龈瘤占比最多,巨细胞性龈瘤最少。完善的炎症控制和彻底的手术切除能够控制牙龈瘤的复发。

关键词: 牙龈瘤, 临床特征, 复发防范

Abstract: Objective: To analyze clinical features of epulis and provide a reference for delving into the biological behavior and prevention of relapse of epulis. Methods: Patients diagnosed as epulis through outpatient and postoperative pathology at the Department of Periodontology, Nanjing Stomatological Hospital, Medical School of Nanjing University from 2018 to 2019 were retrospectively analyzed. Results: A total of 234 cases of epulides were included. The peak incidence of epulis fell in 21 to 30 years old, and the total ratio of males to females was about 1∶2.2. Female was more frequent in the group from 31 to 70 years (P<0.05), yet there was no statistically difference in the proportion of male and female under the age of 30 (P>0.05). Histopathological examination revealed fibrous epulis (121 cases, 51.71%), granuloma epulis (76 cases, 32.48%), vascular epulis (36 cases, 15.38%), and giant cell epulis (1 case, 0.43%). There was no significant difference in the distribution of the upper and lower jaws of epulis (P>0.05), and the anterior teeth area was the common location (P<0.001). In addition, epulis were mostly located on the buccal side (66.67%) and least in the edentulous area (1.28%). The size of epulis varied from 0.3 cm to 2.2 cm in diameter, most of which were distributed among the range of 0.6 cm to 1.5 cm (78.2%). Two cases had relapsed after periodontal system treatment in the short term, and the recurrence rate was 0.85%. Conclusion: Epulides are more prevalent in females and young patients(21 to 30 years old). The majority of epulides were located in the anterior region and on the buccal side. Perfect inflammation control and thorough surgical resection can effectively control the recurrence of epulis.

Key words: epulis, clinical features, relapse prevention