应用激光散斑衬比成像探究牙龈生物型对正畸加力下牙龈血流变化的影响

doi:10.13701/j.cnki.kqyxyj.2024.06.011

口腔医学研究 ›› 2024, Vol. 40 ›› Issue (6): 530-536.DOI: 10.13701/j.cnki.kqyxyj.2024.06.011

应用激光散斑衬比成像探究牙龈生物型对正畸加力下牙龈血流变化的影响

尹凡^1,2, 韩爽^2*, 安琪², 王占礼^2,3, 耿荣光^1,2, 赵军伟⁴

1.蚌埠医科大学口腔医学院安徽蚌埠 233030;
2.安徽医科大学合肥口腔临床学院,合肥市口腔医院正畸二科安徽合肥 230001;
3.皖南医学院口腔医学院安徽芜湖 241002;
4.安徽省儿童医院口腔科安徽合肥 230051

收稿日期:2024-02-18 出版日期:2024-06-28 发布日期:2024-06-19
通讯作者: * 韩爽,E-mail:ellenhan623@126.com
作者简介:尹凡(1999~ ),女,山东济宁人,硕士在读,研究方向:口腔正畸学。
基金资助:
2023年蚌埠医学院研究生科研创新计划项目(编号:Byycx23073)；2023年合肥市卫计委应用医学研究项目(编号:Hwk2023zd019)；2022年安徽省重点研究与开发计划项目(编号:2022e07020059)；2021年合肥市关键共性技术研发和重大科技成果工程化项目(编号:2021YL008)；2021年安徽医科大学校科研基金项目(编号:2021xkj250)

Effect of Gingival Biotype on Changes in Gingival Blood Flow under Orthodontic Forces Investigated by Laser Speckle Contrast Imaging

YIN Fan^1,2, HAN Shuang^2*, AN Qi², WANG Zhanli^2,3, GENG Rongguang^1,2, ZHAO Junwei⁴

1. School of Stomatology, Bengbu Medical College, Bengbu 233030, China;
2. Hefei Clinical College of Stomatology, Anhui Medical University, Hefei Stomatological Hospital, Orthodontics Department Two, Hefei 230001, China;
3. School of Stomatology, Wannan Medical College, Wuhu 241002, China;
4. Department of Stomatology, Anhui Children's Hospital, Hefei 230051, China

Received:2024-02-18 Online:2024-06-28 Published:2024-06-19

摘要/Abstract

摘要： 目的:应用激光散斑衬比成像(laser speckle contrast imaging,LSCI)探究牙龈生物型对正畸加力下牙龈血流变化的影响。方法:招募24例符合纳入标准的受试者参与研究,包括薄龈型组12例,厚龈型组12例,随机在每例受试者上颌左侧或右侧的尖牙至第一磨牙间施加150 g的力,并在施力前、施力30 min、1 d、3 d、7 d、14 d分别使用LSCI动态监测施力侧尖牙区牙龈血流灌注。结果:组间比较,薄龈型组与厚龈型组各时间点的血流值比较均存在显著差异,厚龈型血流值显著高于薄龈型(P＜0.05);组内比较,每组各时间点的血流值比较也存在显著差异(P＜0.05),施力后,局部血流灌注在30 min~1 d内降至最小值,7 d左右上升至最大值,14 d时基本恢复到基线。在没有力值加载的静息状态下,游离龈与牙间乳头的血流值比较存在显著差异(P＜0.05),游离龈血流值显著低于牙间乳头。结论:LSCI是正畸加力过程中实时监测牙龈血流灌注的良好工具,薄龈型血液供应显著低于厚龈型。

关键词: 激光散斑衬比成像, 牙龈血流, 牙龈生物型, 牙周健康

Abstract: Objective: To explore the effect of gingival biotype on gingival blood flow (BF) changes under orthodontic forces by laser speckle contrast imaging (LSCI). Methods: The study recruited a total of 24 subjects who met the inclusion criteria, with 12 individuals allocated to the thin gingival group and another 12 allocated to the thick gingival group. A force of 150 g was randomly applied between either the left or right maxillary canines and the first molar in each volunteer. Subsequently, dynamic monitoring of BF using LSCI was conducted at various time points: before force application, at 30 minutes, 1 day, 3 days, 7 days, and 14 days. Results: Through inter group comparison, there were significant differences in BF between the thin group and the thick group at various time points, with the BF of the thick group significantly higher than that of the thin group (P<0.05). After intra group comparison, there were significant differences in BF at each time point in each group (P<0.05). After applying force, local BF decreased to the minimum value within 30 minutes to 1 day, rose to the maximum value around 7 days, and basically returned to the baseline by 14 days. In a resting state without force loading, there was a significant difference in BF between the free gingiva and interdental papilla (P<0.05), and the BF of the free gingiva was significantly lower than that of the interdental papilla area. Conclusion: LSCI is a useful tool to real-time monitor gingival BF during orthodontic treatment. The BF of thin gingival type was significantly lower than that of thick gingival type.

Key words: laser speckle contrast imaging, gingival blood flow, gingival biotype, periodontal health

尹凡, 韩爽, 安琪, 王占礼, 耿荣光, 赵军伟. 应用激光散斑衬比成像探究牙龈生物型对正畸加力下牙龈血流变化的影响[J]. 口腔医学研究, 2024, 40(6): 530-536.

YIN Fan, HAN Shuang, AN Qi, WANG Zhanli, GENG Rongguang, ZHAO Junwei. Effect of Gingival Biotype on Changes in Gingival Blood Flow under Orthodontic Forces Investigated by Laser Speckle Contrast Imaging[J]. Journal of Oral Science Research, 2024, 40(6): 530-536.

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应用激光散斑衬比成像探究牙龈生物型对正畸加力下牙龈血流变化的影响

Effect of Gingival Biotype on Changes in Gingival Blood Flow under Orthodontic Forces Investigated by Laser Speckle Contrast Imaging

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