口腔医学研究

口腔医学研究 ›› 2016, Vol. 32 ›› Issue (4): 326-330.DOI: 10.13701/j.cnki.kqyxyj.2016.04.003

• 基础研究论著 • 上一篇    下一篇

持续或间断应力加载下正畸微种植体稳定性的组织形态学和生物力学分析

吴也可1,3*,赵立星2,3   

  1. 1. 成都中医大学附属医院口腔科 四川 成都 610072;
    2. 四川大学华西口腔医院正畸科 四川 成都 610041;
    3. 四川大学口腔疾病研究国家重点实验室 四川 成都 610041
  • 收稿日期:2015-10-14 出版日期:2016-04-28 发布日期:2016-04-28
  • 通讯作者: 吴也可,E-mail:337872366@qq.com
  • 作者简介:吴也可(1987~ ),男,成都人,主治医师,博士,主要从事口腔正畸学临床及基础的研究工作。
  • 基金资助:
    国家自然科学基金(编号:81500818)国家自然科学基金(编号:81300876)

Histomorphometric and Biomechanical Analysis of Orthodontic Microscrews Stability under Continuous or Intermittent Force.

WU Ye-ke1,3*,ZHAO Li-xing2,3.   

  1. 1. Department of Stomatology, Affiliated Hospital of Chengdu University of TCM, Chengdu 610072, China;
    2. Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China;
    3. State Key Laboratory of Oral Diseases, Sichuan University, Chengdu 610041, China
  • Received:2015-10-14 Online:2016-04-28 Published:2016-04-28

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摘要： 目的:研究持续或间断应力加载对正畸微种植体稳定性的影响。方法:将144枚微种植体植入36只Beagle犬两侧上颌骨第一磨牙和第二前磨牙根间区域,持续组(n=12)连续加载应力,间断A组(n=12)和B组(n=12)分别以12和24 h为周期间断加载应力。术后1、3、5、7周处死,作显微CT和力学拉拔测试。结果:3组显微CT指标均随时间延长逐渐上升,而Fmax在第5周达峰值,第7周略有下降。在所有时间点,持续组的所有指标均低于两个间断组,且间断组A的各项指标均高于间断组B。结论:间断相比持续应力加载更有利于微种植体稳定性的获得,且12 h的加载周期比24 h更能促进骨-微种植体结合。

关键词: 骨-微种植体结合, 持续应力, 间断应力, 微种植体, 稳定性

Abstract: Objective: To evaluate the influence of continuous or intermittent force on stability of titanium microscrews. Methods: 144 microscrews were inserted bilaterally in intraradicular zones of maxillary first molar and second premolar in 36 beagles. Loads were delivered consecutively in continuous group (n=12), in cycles of 12 on/paused for 12h in intermittent group A (n=12), and in cycles of 24 on/paused for 24h in intermittent group B (n=12). The on/off cycles were repeated for 1, 3, 5 or 7 weeks, after which the animals were sacrificed, and microscopic computerized tomography (μCT) and pullout test were applied. Results: The μCT parameters of microscrews in all three groups increased gradually with loading time. Fmax increased and reached a peak at week 5 but dropped slightly at week 7. In continuous group, all measurements were lower than those in intermittent groups at all time points. All values in intermittent group A were higher than those in intermittent group B. Conclusion: An intermittent loading regimen appears to be more favorable for obtaining stability than continuous loading, and a 12 h/12 h on/off loading cycle is superior to a 24 h/24 h on/off protocol in promoting bone-implant contact.

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