MicroRNAs与肿瘤血管生成

doi:10.13701/j.cnki.kqyxyj.2017.08.025

摘要/Abstract

摘要： 血管生成是指在现有血管基础上生成新血管结构的过程,与肿瘤发生发展密切相关。新生的血管既为肿瘤生长提供营养支持,又参与肿瘤转移、复发、耐药等诸多生物学行为。MicroRNAs作为重要的调节方式,在肿瘤血管生成中扮演的的角色尤为突出。本文就microRNAs在不同肿瘤中参与血管生成的相关机制作一综述。

关键词: 微小RNA, 血管生成, 肿瘤

Abstract: Angiogenesis, the process of forming neovascular structure from preexisting blood vessels, is closely related with tumor growth, metastasis, relapse, drug resistance via the supply of nutrients and grow factors. In this complicated regulatory network of tumor angiogenesis, microRNAs play an important role and even act as an accurate biomarker or therapeutic target. In this paper, the effects of microRNAs on tumor angiogenesis were summarized.

Key words: MicroRNAs, Angiogenesis , Tumor

中图分类号:

R782

夏厚福, 任建岗, 赵怡芳. MicroRNAs与肿瘤血管生成[J]. 口腔医学研究, 2017, 33(8): 901-904.

XIA Hou-fu, REN Jian-gang, ZHAO Yi-fang.. MicroRNAs and Tumor Angiogenesis.[J]. Journal of Oral Science Research, 2017, 33(8): 901-904.

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