口腔医学研究

口腔医学研究 ›› 2022, Vol. 38 ›› Issue (12): 1187-1191.DOI: 10.13701/j.cnki.kqyxyj.2022.12.017

• 儿童口腔医学研究 • 上一篇    下一篇

原发性肾病综合征儿童口腔健康状况调查

汪明敏, 孔楠楠, 郭雪艳, 李亚奇*   

  1. 西安市儿童医院口腔科 陕西 西安 710000
  • 收稿日期:2022-05-16 出版日期:2022-12-28 发布日期:2022-12-26
  • 通讯作者: *李亚奇,E-mail:yaqilee2008@163.com
  • 作者简介:汪明敏(1989~ ),女,浙江人,硕士,主治医师,研究方向:儿童口腔医学。
  • 基金资助:
    中华口腔医学会西部口腔医学临床科研基金项目(编号:CSA-W2020-02)

A Survey on Oral Health Status in Children with Primary Nephrotic Syndrome

WANG Mingmin, KONG Nannan, GUO Xueyan, LI Yaqi*   

  1. Department of Stomatology, Xi'an Children's Hospital, Xi'an 710000, China
  • Received:2022-05-16 Online:2022-12-28 Published:2022-12-26

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摘要： 目的: 了解国内原发性肾病综合征儿童的口腔健康状况,探讨其口腔相关危险因素。材料: 选取120名3~6岁原发性肾病儿童作为实验组,120名健康儿童作为对照组进行口腔健康调查。结果: 实验组和对照组患龋率、dmft均值、龋态值中位数、 PLI中位数、GI中位数、根尖瘘管发生率、釉质发育不全发生率、sIgA中位数分别为85.8%和74.2%(P<0.05),(6.69±4.71)和(5.16±4.69)(P<0.05),2.0(1.0)和1.75(1.5)(P<0.05),1.6(0.9)和1.35(1.3)(P>0.05),1.00(0.28)和0.65(0.7)(P<0.05),10.8%和3.33%(P<0.05),5.80%和3.33%(P>0.05),4.65(4.61) μg/mL和1.08(0.99) μg/mL(P<0.05)。患龋(OR=2.110,95%CI=1.095~4.067),根尖瘘管(OR=3.523,95%CI=1.114~11.139)与PNS有关。结论: 3~6岁PNS儿童在发病初期比健康儿童患龋情况更严重,患龋风险更高,牙龈炎症更重。龋病以及慢性根尖周炎可能与PNS发病存在一定相关性。

关键词: 原发性肾病综合征, 口腔健康, 危险因素

Abstract: Objective: To assess the oral health status of children with primary nephrotic syndrome and to explore the oral related risk factors. Methods: One hundred and twenty children aged 3-6 years with primary nephrotic syndrome were recruited as the experimental group and 120 healthy children as the control group for oral examination. Results: The incidence of caries, mean dmft, median Cariostat scores, median PLI, median GI, incidence of apical fistula, incidence of enamel hypoplasia, and median sIgA levels in the experimental group and the control group were 85.8% and 74.2% (P<0.05), 6.69±4.71 and 5.16±4.69 (P<0.05), 2.0 (1.0) and 1.75 (1.5) (P<0.05), 1.6 (0.9) and 1.35 (1.3) (P>0.05), 1.00 (0.28) and 0.65 (0.7) (P<0.05), 10.8% and 3.33% (P<0.05), 5.80% and 3.33% (P>0.05), and 4.65 (4.61) μg/mL and 1.08 (0.99) μg/mL (P<0.05), respectively. Caries OR=2.110, 95%CI=1.095-4.067, apical fistula OR=3.523, 95%CI=1.114-11.139. Conclusion: 3-6 years PNS children have more serious caries than healthy children at the onset of the disease, with higher risk of caries and more severe gingival inflammation. Caries and chronic periapical periodontitis may be corelated with the occurrence of PNS.

Key words: nephrotic syndrome, oral health, risk factors