Periostin在牙周膜作用的研究进展

doi:10.13701/j.cnki.kqyxyj.2019.07.005

摘要/Abstract

摘要： Periostin为一种细胞外基质蛋白,由成骨细胞及其前体细胞分泌。在骨膜及纤维结缔组织中表达,参与骨修复过程,有促进成骨及胶原纤维形成作用。在牙齿发育的帽状期及钟状期和牙齿萌出过程中,Periostin发挥着十分重要作用,特别是在牙周膜的修复再生中。Periostin还是机械应力下骨和牙周膜改建过程中的重要局部促进因素。本文就Periostin在牙周膜作用中的相关研究进展进行综述。

关键词: Periostin, 细胞外基质蛋白, 牙周膜

Abstract: Periostin is an extracellular matrix proteins, secreted by the osteoblast and its precursor cells. It is expressed in periosteum and fibrous connective tissue and involved in bone repair. It can promote the formation of bone and collagen fibers. Periostin plays a very important role in the process of cap stage, bell stage, and tooth eruption, especially in the repair and regeneration of periodontal ligament. Periostin is also an impormant local promoting factor in bone and periodontal tissue reconstruction under mechanical sterss. The present paper reviews the related development of periostin reserach on the function of periodontal ligament

Key words: Periostin, extracellular matrix proteins, periodontal ligament

丁瑞霞, 王慧明. Periostin在牙周膜作用的研究进展[J]. 口腔医学研究, 2019, 35(7): 635-638.

DING Ruixia, WANG Huiming. Research of Periostin in the Function of Periodontal Ligament[J]. Journal of Oral Science Research, 2019, 35(7): 635-638.

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