外泌体在口腔组织发育和再生研究新进展

doi:10.13701/j.cnki.kqyxyj.2019.11.002

口腔医学研究 ›› 2019, Vol. 35 ›› Issue (11): 1016-1019.DOI: 10.13701/j.cnki.kqyxyj.2019.11.002

外泌体在口腔组织发育和再生研究新进展

石维薇^1,2, 郭淑娟^1,2*

1. 口腔疾病研究国家重点实验室,国家口腔疾病临床医学研究中心四川成都 610041;
2. 四川大学华西口腔医院牙周病科四川成都 610041

收稿日期:2018-12-24 出版日期:2019-11-28 发布日期:2019-11-21
通讯作者: 郭淑娟,E-mail:guo.shujuan@yahoo.com
作者简介:石维薇(1994~ ),女,湖南人,硕士在读,研究方向为牙周组织再生。
基金资助:
国家自然科学基金青年基金项目(编号:81200792)

Recent Advancement in Development and Regeneration of Exosomes in Oral Tissues

SHI Weiwei^1,2, GUO Shujuan^1,2*

1.State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China;
2. Department of Periodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China

Received:2018-12-24 Online:2019-11-28 Published:2019-11-21

摘要/Abstract

摘要： 外泌体(exosome)是细胞外囊泡亚组份,作为纳米级信号分子在细胞、组织和器官之间传递生物分子信息,促进机体血管再生、损伤组织修复。而在口腔中,外泌体不仅可以调控牙、骨、唾液腺等组织发生发育,还可以促进颌面组织创伤修复和牙髓、牙周组织再生。本文将对外泌体在口腔组织发育和再生中的作用研究新进展做一综述。

关键词: 外泌体, 口腔组织发育, 干细胞, 牙髓再生, 牙周再生

Abstract: Exosomes secreted by cells are small vesicles. As a nanoscale signal molecule, exosomes play a key role in the communication among cells, tissue, and organs. Recently, studies demonstrate that exosomes can promote angiogenesis, wound healing, and bone regeneration. This paper reviewed relevant studies about the effect of exosomes on promting the organogenesis and regeneration of oral tissue.

Key words: exosomes, oral tissue development, stem cell, dental pulp regeneration, periodontal regeneration

石维薇, 郭淑娟. 外泌体在口腔组织发育和再生研究新进展[J]. 口腔医学研究, 2019, 35(11): 1016-1019.

SHI Weiwei, GUO Shujuan. Recent Advancement in Development and Regeneration of Exosomes in Oral Tissues[J]. Journal of Oral Science Research, 2019, 35(11): 1016-1019.

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外泌体在口腔组织发育和再生研究新进展

Recent Advancement in Development and Regeneration of Exosomes in Oral Tissues

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