口腔医学研究 ›› 2022, Vol. 38 ›› Issue (7): 647-649.DOI: 10.13701/j.cnki.kqyxyj.2022.07.013

• 儿童龋病研究 • 上一篇    下一篇

模拟口腔环境下的乳牙脱矿及再矿化研究

高黎1*, 张慧1, 王蕊1, 陶慧骞2, 刘玲1, 姜文敬1, 王梦瑶1, 李林林1, 闫波1   

  1. 1.郑州大学第一附属医院口腔科 郑州大学口腔医学院 河南 郑州 450000;
    2.浙江大学医学院附属口腔医院 浙江 杭州 310000
  • 收稿日期:2022-01-06 出版日期:2022-07-28 发布日期:2022-07-22
  • 通讯作者: * 高黎,E-mail:gaolidoc@126.com
  • 作者简介:高黎(1973~ ),女,河南人,博士,副主任医师,主要从事儿童口腔研究。

Demineralization and Remineralization of Deciduous Teeth in Simulated Oral Environment

GAO Li1*, ZHANG Hui1, WANG Rui1, TAO Huiqian2, LIU Ling1, JIANG Wenjing1, WANG Mengyao1, LI Linlin1, YAN Bo1   

  1. 1. Department of Stomatology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou University College of Oral Medicine, Zhengzhou 450000, China;
    2. The Affiliated Hospital of Stomatology, School of Stomatology, Zhejiang University School of Medicine, Hangzhou 310000, China
  • Received:2022-01-06 Online:2022-07-28 Published:2022-07-22

摘要: 目的:采用流速控制装置模拟口腔环境,为乳牙脱矿及再矿化研究提供参考。方法:收集并制备40个乳牙牙釉质标本,随机分为4组,实验组为屈臣氏苏打汽水组、统一鲜橙多组、可口可乐组,人工唾液为对照组。每组5个涂氟,5个未涂氟。流动装置进行脱矿及再矿化。扫描电镜观察釉质表面超微结构。结果:随着饮料pH值降低,釉质表面的矿物溶解程度逐渐加重;涂氟后脱矿程度减轻,表面有矿化物质沉积。结论:本实验采用一种流动装置进行研究,成功展示了动态环境下酸性饮料对乳牙牙釉质的动态脱矿作用及多乐氟的再矿化作用,具有良好的实际意义。

关键词: 模拟, 口腔动态环境, 流速控制装置, 脱矿, 再矿化

Abstract: Objective: To study demineralization and remineralization of deciduous teeth in a flowing device simulating oral environment. Methods: Forty enamel specimens were collected and randomly divided into four groups: Watson soda group, fresh orange group, Coca-Cola group, and artificial saliva group (control group). In each group, five specimens were fluorinated and another five were un-fluorinated. Dental demineralization and remineralization were performed by a flowing device. The surface structure of the enamel was observed by scanning electron microscopy (SEM). Results: Under electron microscope, the degree of mineral dissolution on the enamel surface was increased when the beverage pH decreased gradually. After fluoriding, demineralization was improved and deposits could be seen. Conclusion: The experiment successfully showed the demineralization of deciduous enamels by acidic beverage and the remineralization by Duraphat using a dynamic flowing device, which had ideal practical significance.

Key words: simulation, oral dynamic environment, velocity controlling device, demineralization, remineralization