口腔医学研究 ›› 2023, Vol. 39 ›› Issue (2): 109-112.DOI: 10.13701/j.cnki.kqyxyj.2023.02.004

• 综述 • 上一篇    下一篇

牙周炎与口腔菌群及肠道菌群的相关研究进展

陈栖1,2,3, 龚婷1,2,3*   

  1. 1.重庆医科大学附属口腔医院 重庆 401147;
    2.口腔疾病与生物医学重庆市重点实验室 重庆 401147;
    3.重庆市高校市级口腔生物医学工程重点实验室 重庆 401147
  • 收稿日期:2022-09-13 出版日期:2023-02-28 发布日期:2023-02-20
  • 通讯作者: * 龚婷,E-mail:gongting@hospital.cqmu.edu.cn
  • 作者简介:陈栖(1994~ ),男,重庆人,硕士在读,研究方向:口腔菌群与肠道菌群的双向关系。
  • 基金资助:
    重庆市自然科学基金博士后科学基金项目(编号:cstc2021jcyjbshX0176)

Research Progress on Relationship between Periodontitis and Oral as well as Gut Microbiota

CHEN Qi1,2,3, GONG Ting1,2,3*   

  1. 1. Stomatological Hospital of Chongqing Medical University, Chongqing 401147, China;
    2. Chongqing Key Laboratory of Oral Diseases and Biomedical Sciences, Chongqing 401147, China;
    3. Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education, Chongqing 401147, China
  • Received:2022-09-13 Online:2023-02-28 Published:2023-02-20

摘要: 肠道菌群为人体最大的微生物群落,近来研究显示,肠道菌群与全身健康息息相关,肠道菌群失调在肥胖症、心脏病、孤独症、糖尿病等疾病中扮演重要角色。牙周炎是最常见的口腔疾病之一,表现为牙槽骨丧失、牙齿松动等。近来研究显示,牙周炎会影响肠道菌群。本文就牙周炎对肠道菌群的影响、作用路径及可能因素做一综述,以期为探究牙周炎与肠道菌群相关性提供参考。

关键词: 牙周炎, 肠道菌群, 口腔菌群

Abstract: The gut microbiota is the largest microbial community in the human body. Recent studies have shown that the gut microbiota is closely related to the health of the whole body. The gut dysbiosis plays an important role in obesity, heart disease, autism, diabetes, et al. Periodontitis is one of the most common oral diseases, manifested as alveolar bone loss, tooth loosening, etc. Recent studies have shown that periodontitis can affect the gut microbiota. This article discusses the effect of periodontitis on the gut microbiota, possible routes, and factors of oral microbiota to influence gut microbiota, in order to provide reference for exploring the correlation between periodontitis and gut microbiota.

Key words: periodontitis, gut microbiota, oral microbiota