口腔医学研究

口腔医学研究 ›› 2026, Vol. 42 ›› Issue (5): 391-397.DOI: 10.13701/j.cnki.kqyxyj.2026.05.006

• 颞下颌关节病学研究 • 上一篇    下一篇

数字化牙合垫治疗颞下颌关节紊乱病初步效果评价分析

魏云鹏1, 郭芮彤2, 孟佳丽3, 陈云4, 施佩花1, 衣颖杰3, 吴国锋3, 赵苏峰1*   

  1. 1.南京大学医学院附属口腔医院口腔颌面外科,南京市口腔医院,南京大学口腔医学研究所 江苏 南京 210006;
    2.南京大学医学院附属口腔医院药学部,南京市口腔医院,南京大学口腔医学研究所 江苏 南京 210006;
    3.南京大学医学院附属口腔医院数字化中心,南京市口腔医院,南京大学口腔医学研究所 江苏 南京 210006;
    4.南京医科大学附属口腔医院儿童预防口腔科,江苏省口腔疾病研究重点实验室,江苏省口腔转化医学工程研究中心 江苏 南京 210029
  • 收稿日期:2025-10-10 发布日期:2026-05-25
  • 通讯作者: *赵苏峰,E-mail:zhaosufengwkmz@163.com
  • 作者简介:魏云鹏(1991~ ),男,主治医师,硕士,研究方向:颞下颌关节疾病。
  • 基金资助:
    南京市口腔医院医疗新技术新项目(编号:NJSH-2023NL-049)

Preliminary Evaluation and Analysis of Digital Occlusal Splint Therapy for Temporomandibular Disorders

WEI Yunpeng1, GUO Ruitong2, MENG Jiali3, CHEN Yun4, SHI Peihua1, YI Yingjie3, WU Guofeng3, ZHAO Sufeng1*   

  1. 1. Department of Oral and Maxillofacial Surgery, Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Research Institute of Stomatology, Nanjing University, Nanjing 210006, China;
    2. Department of Pharmacy, Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Research Institute of Stomatology, Nanjing University, Nanjing 210006, China;
    3. Department of Digital Engineering Center, Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Research Institute of Stomatology, Nanjing University, Nanjing 210006, China;
    4. Department of Pediatric Dental Prevention, Affiliated Stomatological Hospial of Nanjing Medical University, Jiangsu Province Key Laboratory of Oral Diseases, Jiangsu Province Engineering Research Center of Stomatological Translational Medicine, Nanjing 210029, China
  • Received:2025-10-10 Published:2026-05-25

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摘要： 目的:介绍一种全程数字化牙合垫治疗颞下颌关节紊乱病的制作方法和治疗流程,并对其临床治疗效果进行初步评价分析。方法:收集2023年5月~2025年2月南京大学医学院附属口腔医院诊断为颞下颌关节紊乱病的患者66例,分为3组,可复性关节盘前移位组,不可复性关节盘前移位组,一侧可复性关节盘前移位和对侧不可复性关节盘前移位组。数字化牙合垫治疗后,采用非参数检验,比较治疗前和治疗后8周,疼痛、饮食、下颌运动功能、生活质量的视觉模拟评分和最大张口度变化(α=0.05)。采用χ2检验分析3组间治疗有效率的差异(α=0.05)。结果:66例患者(男19例,女47例)纳入研究,平均年龄(25.92±9.92)岁,平均随访时间(10.92±11.27)周。数字化牙合垫治疗后,患者疼痛、饮食、下颌运动功能和生活质量均有显著改善(P<0.05),有效率分别为73.2%、76.9%、71.9%和74.1%。与不可复性关节盘前移位患者相比,可复性关节盘前移位患者采用数字化牙合垫治疗后,下颌运动功能改善效果更显著(P=0.005)。结论:数字化牙合垫治疗颞下颌关节紊乱病临床效果显著。对于下颌运动功能障碍的可复性关节盘前移位患者,数字化牙合垫治疗效果更好。

关键词: 颞下颌关节紊乱病, 数字化牙合垫, 可复性关节盘前移位, 不可复性关节盘前移位

Abstract: Objective: To introduce the manufacturing method and treatment process of a full-range digital occlusal splint in the treatment of temporomandibular disorders, and to evaluate its therapeutic effect preliminarily. Methods: From May 2023 to February 2025, 66 patients diagnosed with temporomandibular disorders in Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Nanjing University were divided into three groups: anterior disc displacement with reduction (ADDwR), anterior disc displacement without reduction (ADDwoR), and unilateral anterior disc displacement with reduction and unilateral anterior disc displacement without reduction. A non-parametric test was used to analyze the changes of visual analog scale scores for pain, diet, mandibular function, and quality of life and maximum interincisal opening before and at least 8 weeks after digital occlusal splint treatment (α=0.05). Chi-square test was used to analyze the difference of treatment efficiency among the three groups (α=0.05). Results: Sixty-six patients (19 males and 47 females) were enrolled, with a mean±standard deviation age of (25.92±9.92) years and a mean ± standard deviation follow-up of (10.92±11.27) weeks. After the digital occlusal splint treatment, the pain, diet, mandibular function, and quality of life were significantly improved (P<0.05), with effective rates of 73.2%, 76.9%, 71.9%, and 74.1%, respectively. Compared to patients with ADDwoR, patients with ADDwR had better mandibular function improvement after digital occlusal splint treatment (P=0.005). Conclusion: The clinical effect of digital occlusal splint in the treatment of temporomandibular disorders is significant. For ADDwR patients with mandibular dysfunction, the therapeutic effect of digital occlusal splint is better.

Key words: temporomandibular disorders, digital occlusal splint, anterior disc displacement with reduction, anterior disc displacement without reduction