应激在颞下颌关节紊乱病发病机制中的作用

doi:10.13701/j.cnki.kqyxyj.2022.06.003

口腔医学研究 ›› 2022, Vol. 38 ›› Issue (6): 501-504.DOI: 10.13701/j.cnki.kqyxyj.2022.06.003

应激在颞下颌关节紊乱病发病机制中的作用

李佳珩, 曹东元^*

陕西省颅颌面精准医学研究重点实验室,西安交通大学口腔医院口腔医学检测中心陕西西安 710004

收稿日期:2021-07-21 出版日期:2022-06-28 发布日期:2022-06-23
通讯作者: * 曹东元,E-mail: dongyuan_cao@hotmail.com
作者简介:李佳珩(1992~),女,陕西西安人,博士在读,研究方向:口腔生物医学。
基金资助:
国家自然科学基金(编号:81971049、81671097)；陕西省重点研发计划项目(编号:2020SF-018)

Role of Stress in the Pathogenesis of Temporomandibular Joint Disorder

LI Jiaheng, CAO Dongyuan^*

Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, Testing Center of Stomatology, Xi'an Jiaotong University College of Stomatology, Xi'an 710004, China

Received:2021-07-21 Online:2022-06-28 Published:2022-06-23

摘要/Abstract

摘要： 颞下颌关节紊乱病(temporomandibular disorder, TMD)是口腔颌面部非牙源性疼痛的主要原因之一。精神心理因素在TMD的发生和发展中起着重要的作用,可直接和/或间接影响TMD患者疼痛相关的生物过程。本文从机体对应激反应的调控机制出发,总结了应激参与TMD及TMD与其他慢性原发性疼痛(chronic primary pain,CPP)共病的相关临床研究和基础研究,并讨论了应激系统参与TMD与其他CPP疾病的潜在发病机制,有助于更好地指导临床治疗。

关键词: 应激, 颞下颌关节紊乱病, 共病, 疼痛

Abstract: Temporomandibular disorder (TMD) is one of the main causes of non-odontogenic pain in the oral and maxillofacial region. Psychological factors play important roles in the occurrence and development of TMD, and may directly and/or indirectly affect the pain-related biological processes of TMD patients. The purpose of this review is to summarize the related clinical and basic research of stress involved in TMD and other chronic primary pain (CPP) comorbidities, and discuss the potential pathogenesis of TMD and other CPP diseases to guide clinical treatment.

Key words: stress, temporomandibular disorder, comorbidity, pain

李佳珩, 曹东元. 应激在颞下颌关节紊乱病发病机制中的作用[J]. 口腔医学研究, 2022, 38(6): 501-504.

LI Jiaheng, CAO Dongyuan. Role of Stress in the Pathogenesis of Temporomandibular Joint Disorder[J]. Journal of Oral Science Research, 2022, 38(6): 501-504.

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应激在颞下颌关节紊乱病发病机制中的作用

Role of Stress in the Pathogenesis of Temporomandibular Joint Disorder

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