Abstract: Objective: To investigate the applicative value of the interactive medical image control system’s (MIMICS) in mandibular tumor resection and reconstruction of mandibular defect with fibula flap and provide reliable basis for precise preoperative designing plan and desirable postoperative reconstructive result. Methods: Between November2014 and December2015, ten patients with mandibular tumor were treated in our department. Their mandible, maxilla and the donor leg received spiral CT scans preoperatively. DICOM data generated from the scanning were imported into MIMICS to observe the safe resection margin, simulate tumor resection, restore the effected side, reconstruct with fibula flap and predict the outcome. According to the preoperative design, the tumor was resected completely, fibula flap was shaped, titanium plate was bent and fixed, and the fibula flap went to position during operation. Results: All operations were completed successfully according to the preoperative plan, and all fibula flaps survived after the operations. Postoperative follow-ups were done 1, 3, 6, 9 and 12 months after operation and panoramic radiograph and CT were taken. All fibula flaps were in good position. Mouth opening of the patients varied from 2 to 3 fingers. All the donor leg fibula wounds healed well, with no obvious complications. All patients were satisfied with the facial aesthetics and the donor leg function. Conclusion: Pre-surgery planning including presurgical evaluation and outcome prediction with the aid of MIMICS which makes use of preoperative CT data in the mandibular tumor resection and defect reconstruction increases the accuracy of the tumor resection, and improves continuity and symmetry of the mandible.

Key words: MIMICS, Mandibular tumor, Defects reconstruction, Fibular flap