口腔医学研究 ›› 2016, Vol. 32 ›› Issue (9): 997-999.DOI: 10.13701/j.cnki.kqyxyj.2016.09.027

• 综述 • 上一篇    

透明质酸支架材料诱导成骨的研究进展

肖芳1,柳毅2,徐高丽1,霍光1*   

  1. 1. 浙江中医药大学口腔医学院 浙江 杭州 310053;
    2. 荷兰阿姆斯特丹牙科研究中心 荷兰 阿姆斯特丹 3004
  • 收稿日期:2015-07-14 出版日期:2016-09-26 发布日期:2016-09-26
  • 通讯作者: 霍光,电话:13634179540
  • 作者简介:肖芳(1993~ ),女,浙江人,硕士在读,主要从事口腔医学基础研究工作。
  • 基金资助:
    浙江省教育厅科研基金项目(Y201327801)

Research Progress of Osteoinduction by Hyalronic Acid Scaffold

XIAO Fang1, LIU Yi2, XU Gao-li1, HUO Guang1*   

  1. 1. School of Stomatology, Zhejiang Chinese Medical University. Hangzhou 310053, China;
    2. ACTA, University of Amsterdam. Amsterdam 3004, The Netherland.
  • Received:2015-07-14 Online:2016-09-26 Published:2016-09-26

摘要: 透明质酸(hyalronic acid ,HA)又称玻尿酸, 由于具有良好的生物相容性、机械强度、可塑性,可作为促进组织修复的生长因子的有效基质,是一种理想的骨诱导支架材料。本文介绍了HA诱导形成骨组织的相关实验,对未来的研究进行了展望。

关键词: 透明质酸, 诱导成骨, 骨组织工程, 支架材料

Abstract: Hyalronic acid (HA) with good physical properties including biocompatibility, mechanical strength, and plasticity is used as the base material of growth factor to help repairing tissue and is considered to be an ideal scaffold material of osteoindunction. This article introduces relevant experiments about HA inducing and producing bone tissue, gives some explanations about the mechanism both in vivo and vitro, and looks forward to the future research.

Key words: Hyalronic acid, Osteoindunction, Bone tissue engineering, Scaffold material

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