口腔医学研究 ›› 2019, Vol. 35 ›› Issue (8): 730-733.DOI: 10.13701/j.cnki.kqyxyj.2019.08.002

• 综述 • 上一篇    下一篇

乳铁蛋白在口腔领域的研究进展

周恬, 康娜*   

  1. 广西医科大学附属口腔医院重点实验室 广西 南宁 530021
  • 收稿日期:2018-07-08 出版日期:2019-08-28 发布日期:2019-08-22
  • 通讯作者: 康娜,E-mail: kangna78@126.com
  • 作者简介:周恬(1992~ ),男,浙江湖州人,硕士在读,主要从事牙合面畸形的矫治及机理的相关研究。
  • 基金资助:
    国家自然科学基金(编号:81360170)

Research Progress of Lactoferrin in Stomatology Medical Domain

ZHOU Tian, KANG Na*   

  1. State Key Laboratory of Oral Diseases, Affiliated Stomatological Hospital of Guangxi Medical University, Nanning 530021, China
  • Received:2018-07-08 Online:2019-08-28 Published:2019-08-22

摘要: 乳铁蛋白是一种具有多种生理功能的非血红素铁结合性糖蛋白,在抗炎、抗菌、抗病毒、抗肿瘤以及免疫调节方面均有重要作用。乳铁蛋白能促进骨骼生长,在生理浓度下能有效刺激成骨细胞增殖和分化,抑制破骨细胞形成。本文对乳铁蛋白在口腔领域的研究进展进行综述,以期对乳铁蛋白有较全面地了解。

关键词: 乳铁蛋白, 正畸, 牙周病, 口腔, 骨吸收

Abstract: Lactoferrin is a non-heme and iron-binding glycoprotein with various physiological functions, which plays an important role in anti-inflammatory, anti-bacterial, anti-viral, anti-tumor, and immune regulation. Lactoferrin can promote bone growth, effectively stimulate the proliferation and differentiation of osteoblasts and inhibit the formation of osteoclasts under physiological concentrations. In this article, the research progress of lactoferrin in stomatology medical domain is reviewed in order to give a comprehensive understanding of lactoferrin.

Key words: lactoferrin, orthodontics, periodontal disease, oral cavity, bone resorption