口腔医学研究 ›› 2020, Vol. 36 ›› Issue (6): 509-511.DOI: 10.13701/j.cnki.kqyxyj.2020.06.002

• 综述 • 上一篇    下一篇

血小板浓缩物促进周围神经再生的研究进展

刘春影, 周延民*   

  1. 吉林大学口腔医学院口腔种植科 吉林 长春 130021
  • 收稿日期:2019-04-22 出版日期:2020-07-03 发布日期:2020-07-06
  • 通讯作者: *周延民,E-mail:zhouym1962@126.com
  • 作者简介:刘春影(1994~ ),女,黑龙江大庆人,硕士,主要从事口腔种植学临床研究。
  • 基金资助:
    吉林省科技发展计划基金(编号:2018KJT084);吉林省卫生厅(编号:2018J074)

Research Progress of Platelet Concentrates in Promoting Peripheral Nerve Regeneration

LIU Chunying, ZHOU Yanmin*   

  1. Department of Oral Implantology, School and Hospital of Stomatology, Jilin University, Changchun 130021, China
  • Received:2019-04-22 Online:2020-07-03 Published:2020-07-06

摘要: 周围神经损伤是口腔临床医学中常见的疾病,可引起不同程度的感觉和运动功能障碍。另外,骨感知对于种植体的长期稳定具有重要意义。血小板浓缩物含有大量的生长因子,能够促进和诱导周围神经的再生修复。因此,利用血小板浓缩物促进损伤神经的恢复以及种植体周围神经的再生成为重要的研究方向。本文就周围神经的再生机制、血小板浓缩物的分类及其在周围神经再生中的作用作一综述。

关键词: 周围神经再生, 血小板浓缩物, 富血小板血浆, 富血小板纤维蛋白, 浓缩生长因子

Abstract: Peripheral nerve injury is a common disease in stomatology, which can cause varying degrees of sensory and motor dysfunctions. In addition, osseoperception plays an important role in the long-term stability of implants. Platelet concentrates contain a large number of growth factors, which can promote and induce the regeneration and repair of peripheral nerves. Therefore, using platelet concentrates to promote the recovery of injured nerves and the regeneration of implant peripheral nerves have become an important research direction. This article reviews the mechanism of peripheral nerve regeneration, the classification of platelet concentrates, and their regeneration effects on peripheral nerve.

Key words: peripheral nerve regeneration, platelet concentrates, platelet-rich plasma, platelet-rich fibrin, concentrated growth factor