口腔医学研究 ›› 2023, Vol. 39 ›› Issue (10): 880-885.DOI: 10.13701/j.cnki.kqyxyj.2023.10.006

• 口腔种植学研究 • 上一篇    下一篇

3D打印个性化钛网应用于引导骨再生术的精度研究

程熠1, 陈岗1, 赵鹏宇1, 赵楠1, 王超2, 陈丹2, 黄海涛1*   

  1. 1.大连医科大学附属第一医院 116000;
    2.北京航空航天大学 生物与医学工程学院 医学科学与工程学院 北京 100083
  • 收稿日期:2023-03-09 出版日期:2023-10-28 发布日期:2023-10-25
  • 通讯作者: *黄海涛,E-mail: hht945@hotmail.com
  • 作者简介:程熠(1996~ ),女,河南新乡人,硕士在读,研究方向:口腔颌面外科学,口腔种植学。
  • 基金资助:
    辽宁省医工联合创新基金(编号:DMU-1&DICPUN202210),国家自然科学基金面上项目(编号:11872135,12072055),北京市自然科学基金(编号:L212063)

Research on Implantation Accuracy of 3D Printing Individualized Titanium Mesh in Guided Bone Regeneration

CHENG Yi1, CHEN Gang1, ZHAO Pengyu1, ZHAO Nan1, WANG Chao2, CHEN Dan2, HUANG Haitao1*   

  1. 1. The First Affiliated Hospital of Dalian Medical University, Dalian 116000, China;
    2. School of Biological Science and Medical Engineering, Beijing University of Aeronautics and Astronautics, Beijing 100083, China
  • Received:2023-03-09 Online:2023-10-28 Published:2023-10-25

摘要: 目的: 研究3D打印个性化钛网(3D printing individualized titanium mesh)在牙槽骨引导骨再生手术过程中的植入精度。方法: 将9例因严重牙槽骨缺损而使用3D打印个性化钛网作为支架材料进行引导骨再生术(guided bone regeneration,GBR)患者的术后即刻和术后6~9个月的CBCT数据进行三维重建,将实际钛网与术前设计钛网模型进行数字化拟合,比较钛网整体偏差及形变角度。结果: GBR术后即刻钛网与术前设计钛网之间平均偏差为(0.76±0.23) mm;术后6~9个月钛网与术前设计钛网之间平均偏差为(0.71±0.19) mm;术后6~9个月钛网与术后即刻钛网之间平均偏差为(0.35±0.11) mm。最大偏差值出现在术后即刻钛网与术前设计钛网之间,为3.50 mm。钛网形变角度结果显示,与术前设计相比,GBR术后即刻钛网的形变角度最大为21.49°,最小为0°,平均为(9.92±8.72)°。钛网形变角度与平均偏差相关性分析结果显示,钛网形变角度越大,其与设计钛网产生的偏差越大。结论: 3D打印个性化钛网应用于牙槽骨引导骨再生术,钛网实际位置及形态较术前设计存在偏差,需要进一步研究提高3D打印个性化钛网在GBR中的植入精度。

关键词: 3D打印个性化钛网, 引导骨再生, 精度, 数字化

Abstract: Objective: To investigate the accuracy of three dimensional printing individualized titanium mesh (3D-PITM) in alveolar bone guided bone regeneration surgery. Methods: CBCT data of 9 patients who underwent guided bone regeneration using 3D-PITM as scaffold material due to severe alveolar bone defects were reconstructed in three dimensions immediately after surgery and 6-9 months after surgery, and the actual titanium mesh was digitally fitted with the preoperative designed titanium mesh model to compare the overall deviation and deformation of the titanium mesh. Results: The average deviation of titanium mesh between immediate post-GBR surgery and preoperative design was (0.76±0.23) mm; between 6-9 months post-GBR surgery and preoperative design was (0.71±0.19) mm; and between 6-9 months post-GBR surgery and immediate post-GBR surgery was (0.35±0.11) mm. The largest deviation value occurred between immediate post-GBR surgery and the preoperative design (3.50 mm). Compared with preoperative design, the largest deformation angle of titanium mesh of immediate post-GBR surgery was 21.49°, the smallest was 0°, and the average was (9.92±8.72)°. The correlation analysis showed that the larger the deformation angle of titanium mesh after GBR surgery, the larger the deviation between it and the preoperative design. Conclusion: The actual position of titanium mesh was still deviated from the preoperative design during 3D-PITM guided bone regeneration. It is necessary to study and improve the accuracy of 3D-PITM guided bone regeneration.

Key words: 3D printing individualized titanium mesh, guided bone generation, accuracy, digital