口腔医学研究

口腔医学研究 ›› 2023, Vol. 39 ›› Issue (12): 1109-1111.DOI: 10.13701/j.cnki.kqyxyj.2023.12.015

• 病例报告 • 上一篇    下一篇

颌下区玻尿酸注射诱发颌面部多间隙感染死亡1例

芶雨柔, 罗磊*, 许彪   

  1. 昆明医科大学附属口腔医院口腔颌面外科 云南 昆明 650106
  • 收稿日期:2023-04-10 出版日期:2023-12-28 发布日期:2023-12-25
  • 通讯作者: * 罗磊,E-mail:luolei1510@qq.com
  • 作者简介:芶雨柔(1997~ ),女,云南曲靖人,硕士,研究方向:口腔颌面外科学。

A Case of Death Caused by Injection of Hyaluronic Acid and Multiple Space Infection in Maxillofacial Region

GOU Yurou, LUO Lei*, XU Biao   

  1. Department of Oral and Maxillofacial Surgery, Stomatology Hospital Affiliated to Kunming Medical University, Kunming 650106, China
  • Received:2023-04-10 Online:2023-12-28 Published:2023-12-25

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摘要： 玻尿酸(hyaluronic acid, HA)又名透明质酸,目前主要应用与医疗美容领域,注射玻尿酸导致的并发症时有发生,导致颌面部间隙感染且致死极为罕见。昆明医科大学附属口腔颌面外科收治1例因注射玻尿酸导致颌下多间隙感染的女性患者,患者注射玻尿酸10 d时开始出现感染征象,注射40 d时治疗不佳收治我院,后经多学科专家会诊,对该患者进行积极的抗感染治疗以及对症支持治疗,患者情况仍持续恶化后死亡。本文就该例玻尿酸注射充填诱发颌面部多间隙感染致死病例进行回顾以及文献复习,供各位临床医生探讨。

关键词: 玻尿酸注射, 并发症, 颌面部多间隙感染

Abstract: Hyaluronic acid is mainly used in the field of medical beauty at present. Complications of hyaluronic acid injection often occur, however, the leading to maxillofacial space infection or even death is extremely rare. A female patient with submandibular multiple space infection caused by injection of hyaluronic acid was admitted to the Department of Oral and Maxillofacial Surgery affiliated to Kunming Medical University. After 10 days of injection of hyaluronic acid, the patient began to show signs of infection. After 40 days of injection, she was admitted to our hospital. After consultation with multidisciplinary experts, the patient was given active anti-infection treatment and symptomatic support treatment. However, the patient's condition continued to deteriorate and finally she died. In this paper, the case was reviewed and the literature was reviewed for discussion by clinicians.

Key words: hyaluronic acid injection, complication, maxillofacial multi-space infection