口腔癌患者健康相关生活质量及其影响因素调查

doi:10.13701/j.cnki.kqyxyj.2016.05.013

口腔医学研究 ›› 2016, Vol. 32 ›› Issue (5): 478-482.DOI: 10.13701/j.cnki.kqyxyj.2016.05.013

口腔癌患者健康相关生活质量及其影响因素调查

肖燕^* ,张沛沛 ,李文鹿, 何巍

郑州大学第一附属医院口腔科河南郑州 450000

收稿日期:2015-04-20 出版日期:2016-05-26 发布日期:2016-05-26
通讯作者: 肖燕,电话:15538399227
作者简介:肖燕(1974~ ),女,河南人,副主任医师,硕士,主要从事口腔科临床治疗工作。
基金资助:
国家青年自然科学基金项目(编号:81402578)

Level and Influencing Factors of Health Related Quality of Life in Patients with Oral Cancer.

XIAO Yan^*, ZHANG Pei-pei, LI Wen-lu, HE Wei.

Department of Stomatolagy, The First Affiliated Hospital of Zhengzhou University. Zhengzhou 450000, China

Received:2015-04-20 Online:2016-05-26 Published:2016-05-26

摘要/Abstract

摘要： 目的:调查口腔恶性肿瘤患者手术后生活质量状况及其影响因素。方法:选择郑州大学第一附属医院口腔颌面外科2011年5月~2013年1月收治的85例口腔恶性肿瘤患者,使用中文版口腔健康影响程度量表(oral health impact profile,OHIP-49)及华盛顿大学头颈肿瘤生活质量量表(University of Washington Quality of Life Scale,UW-QOL),在患者术后至少12个月后进行生活质量评测。结果:发出问卷85份,回收76份,完成问卷调查89.4%。UW-QOL调查问卷得分最高的项目是疼痛(77.3±6.3)分,其次是焦虑(76.4±7.8)分,第三是活力(74.3±8.2)分;得分最低的3项依次是:咀嚼(34.5±8.3)分、唾液(46.4±4.8)分、味觉(49.9±3.9)分。OHIP-14量表得分最好的项目是残障(38.5±7.4)分,其次是生理性疼痛(46.8±10.2)分,第三是心理障碍(50.9±5.8);得分差的3项依次是:功能限制(62.4±12.3)分、心理不适(57.8±9.2)分、社交障碍(55.8±12.8)分。结论:口腔癌根治性治疗对患者生活质量有显著的影响。对口腔恶性肿瘤应切实做好疾病护理,同时加强营养支持和心理疏导,并加强社会支持。

关键词: 口腔癌, 生活质量, 游离皮瓣

Abstract: Objective: To investigate the level and influencing factors of health related quality of life (HRQoL) in patients with oral cancer. Methods: Totally 85 patients who had had oral cancer surgery between May 2011 and January 2013 in the Department of Stomatology at the First Affiliated Hospital of Zhengzhou University were eligible. HRQoL of patients was assessed by means of the 14-item oraI health impact profile (OHIP-14) and University of Washington Quality of Life (UW-QOL) questionnaires 12 months after operation. Results:76 questionnaires were collected (89.4%). UW-QOL: The highest-scoring domains were pain (77.3±6.3), anxiety (76.4±7.8) and activity (74.3±8.2), the lowest scoring domains were chewing (34.5±8.3), followed by saliva (46.4±4.8) and taste (49.9±3.9). OHIP-14: the best scoring domains were handicap (38.5±7.4), physical pain (46.8±10.2) and psychological disability (50.9±5.8), the worst-scoring domains were functional limitation (62.4±12.3), psychological discomfort (57.8±9.2) and physical pain (55.8±12.8). Conclusion:Oral cancer surgery could significantly influence the patients’ HRQoL. In order to improve the HRQoL of patients with oral cancer, nurses should make efforts to do well in nursing and strengthen nutritional support, psychological guidance and social support.

中图分类号:

R739.8

肖燕 ,张沛沛 ,李文鹿, 何巍. 口腔癌患者健康相关生活质量及其影响因素调查[J]. 口腔医学研究, 2016, 32(5): 478-482.

XIAO Yan, ZHANG Pei-pei, LI Wen-lu, HE Wei.. Level and Influencing Factors of Health Related Quality of Life in Patients with Oral Cancer.[J]. Journal of Oral Science Research, 2016, 32(5): 478-482.

参考文献

[1] Warnakulasuriya S. Living with oral cancer: Epidemiology with particular reference to prevalence and life-style changes that influence survival [J]. Oral Oncol, 2010, 46(6)∶407-410
[2] Juanfang Zhu,Yanjie Yang,Wenlu Li.Assessment of quality of life and sociocultural aspects in patients with ameloblastoma after immediate mandibular reconstruction with a fibular free flap [J]. Br J Oral Maxillofac Surg, 2013, 52(2)∶497-501
[3] Wenlu Li, Zhongfei Xu, Fayu Liu, et al. Vascularized free forearm flap versus free anterolateral thigh perforator flaps for reconstruction in patients with head and neck cancer: assessment of quality of life [J]. Head and Neck, 2013, 35(12)∶1808-13
[4] Murphy BA, Ridner S, Wells N, et al. Quality of life research in head and neck cancer: A review of the current state of the science [J]. Critical Reviews in Oncology/Hematology, 2007, 62(3)∶251-267
[5] Koller M, Klinkhammer-Schalke M, Lorenz W. Outcome and quality of life in medicine: a conceptual framework to put quality of life research into practice [J]. Urol Oncol, 2005, 23(3)∶186-192
[6] Slade GD, Spencer AJ. Development and evaluation of the Oral Health Impact Profile [J]. Community Dental Health, 1994, 11(1)∶3-11
[7] Petti S, Scully C. Oral cancer knowledge and awareness: primary and secondary effects of an information leaflet [J]. Oral Oncol, 2007, 43(4)∶408-415
[8] Choi SY, Kahyo H. Effect of cigarette smoking and alcohol consumption in the etiology of cancer of the oral cavity, pharynx and larynx [J]. Int J Epidemiol, 1991, 49(3)∶381-386
[9] Slade GD. Derivation and validation of a short-form oral health impact profile [J]. Community Dent Oral Epidemiol, 1997, 25(4)∶284-290
[10] 左雯鑫,李晓宇,陈艳卿,等.口腔扁平苔藓患者口腔健康相关生活质量的初步研究[J].华西口腔医学杂志,2012,30(1)∶40-44
[11] Hsing CY, Wong YK, Wang CP, et al. Comparison between free flap and pectoralis major pedicled flap for reconstruction in oral cavity cancer patients-a quality of life analysis [J]. Oral Oncology, 2011, 47(13)∶522-527
[12] Rogers SN, Laher SH, Overend L, et al. Importance-rating using the University of Washington Quality of Life questionnaire in patients treated by primary surgery for oral and oro-pharyngeal cancer [J]. Journal of Cranio-Maxillo-Facial Surgery, 2002, 30(2)∶125-32
[13] Hara I, Gellrich NC,Düber J, et al. Evaluation of swallowing function after intraoral soft tissue reconstruction with microvaseular free flaps [J]. Int J Oral Maxillofac Surg,2003,32(6)∶593-599
[14] 成雨生,李文鹿,许磊,等.前臂游离皮瓣修复口腔癌术后组织缺损患者的生活质量评估[J].中华口腔医学杂志,2013,48(3)∶161-164
[15] Petruson KM, Silander EM, Hammerlid EB. Quality of life as predictor of weight loss in patients with head and neck cancer [J]. Head and Neck, 2005, 27(4)∶302-10
[16] Pauloski BR, Rademaker AW, Logemann JA, Colangelo LA. Speech and swallowing in irradiated and non-irradiated postsurgical cancer patients [J]. Otolaryngology-Head and Neck Surgery,1998, 118(5)∶616-624

口腔癌患者健康相关生活质量及其影响因素调查

Level and Influencing Factors of Health Related Quality of Life in Patients with Oral Cancer.

PDF (PC)

可视化

被引次数

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 15

编辑推荐

Metrics

[1]	尹寿成, 徐中飞. 头颈部缺损修复重建中受区静脉的比较分析[J]. 口腔医学研究, 2020, 36(11): 1004-1006.
[2]	宋勇, 马婷婷, 王俊林, 刘彦杰, 陈裕聪, 何浒杰. 带蒂皮瓣法构建裸鼠低氧口腔癌模型[J]. 口腔医学研究, 2019, 35(12): 1125-1128.
[3]	郭丰源, 李文强, 许智, 黄春明, 胡传宇. 任氏血管吻合法在口腔颌面部缺损修复中的应用及评价[J]. 口腔医学研究, 2019, 35(11): 1048-1051.
[4]	孙维克, 王培源, 刘伟, 王霞. Beclin1与凋亡相关蛋白在口腔鳞癌中的表达及意义[J]. 口腔医学研究, 2019, 35(10): 979-983.
[5]	洪鹏宇, 高陆, 邱冠华, 全宏志, 唐瞻贵. 前臂皮瓣与股前外侧皮瓣修复口腔癌术后缺损临床研究[J]. 口腔医学研究, 2019, 35(1): 46-50.
[6]	胡慧珍,王世琴,孙贵军,金佳佳,李志勇,何祥一. 口腔鳞状细胞癌外泌体mRNA表达图谱分析[J]. 口腔医学研究, 2018, 34(9): 943-947.
[7]	秦帅华, 李新明, 李文鹿. 修复重建后口腔癌患者生存质量的影响因素分析[J]. 口腔医学研究, 2018, 34(2): 144-147.
[8]	田原野,李洪远,李君萍,唐瞻贵. 7,12-二甲基苯并[a]蒽诱发叙利亚地鼠颊鳞状细胞癌模型中Th1/Th2、Th17/Treg平衡变化研究[J]. 口腔医学研究, 2018, 34(12): 1284-1288.
[9]	钟洁,陈小贤,张红梅,姜霞,黄芊. 全麻下全口牙病治疗对残障儿童生活质量的影响[J]. 口腔医学研究, 2018, 34(12): 1312-1315.
[10]	孙莹, 于大海, 王涛, 温琦涛, 邓桂祥, 黄康. 槟榔碱对口腔癌患者及小鼠肝脏功能影响的初步研究[J]. 口腔医学研究, 2017, 33(6): 589-592.
[11]	冯雪峰, 黄海涛, 王如. 口腔癌患者就医延迟现状及其影响因素分析[J]. 口腔医学研究, 2016, 32(7): 716-719.
[12]	孟沙沙, 介亚琼 ,韩新光 ,孙晓静. 颏下岛状瓣修复软腭及磨牙后区缺损[J]. 口腔医学研究, 2016, 32(5): 521-523.
[13]	韩影,苏彤,林璐,钱韵梅,熊浩峰. 口腔癌对侧颈淋巴结转移的临床研究[J]. 口腔医学研究, 2016, 32(2): 154-157.
[14]	张偲, 刘苗苗, 刘佩琦, 贾荣, 郭继华. HnRNP L调控口腔癌细胞中CD55内含子7的可变剪切的研究[J]. 口腔医学研究, 2016, 32(10): 1006-1009.
[15]	杨艳青,袁杰,张磊,叶珑伟,黄鑫,张晓丹,李楠. 血卟啉单甲醚荧光光谱法辅助诊断早期口腔癌[J]. 口腔医学研究, 2015, 31(7): 699-701.